| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0911716 |
| CLU | clusterin | 0.0768036 |
| B2M | beta-2-microglobulin | 0.0714896 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.071296 |
| FKBP5 | FK506 binding protein 5 | 0.0572376 |
| MT2A | metallothionein 2A | 0.0558471 |
| RBM39 | RNA binding motif protein 39 | 0.0542662 |
| ANXA1 | annexin A1 | 0.0519517 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0519396 |
| KRT6A | keratin 6A, type II | 0.0514819 |
| EZR | ezrin | 0.05069 |
| EMP1 | epithelial membrane protein 1 | 0.0496481 |
| ANLN | anillin, actin binding protein | 0.048399 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0480999 |
| TOP1 | topoisomerase (DNA) I | 0.0456484 |
| STC1 | stanniocalcin 1 | 0.0456373 |
| MYOF | myoferlin | 0.0455726 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0450007 |
| TXNIP | thioredoxin interacting protein | 0.0445952 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0432748 |
| MT1X | metallothionein 1X | 0.0420605 |
| NDRG1 | N-myc downstream regulated 1 | 0.0419386 |
| ENO1 | enolase 1, (alpha) | 0.0413008 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0412678 |
| PTMA | prothymosin, alpha | 0.0411762 |
| AHNAK | AHNAK nucleoprotein | 0.0405522 |
| TPM3 | tropomyosin 3 | 0.0376266 |
| DSTN | destrin (actin depolymerizing factor) | 0.0375239 |
| PGK1 | phosphoglycerate kinase 1 | 0.036975 |
| SQLE | squalene epoxidase | 0.0355078 |
| TMSB4X | thymosin beta 4, X-linked | 0.0352991 |
| GOLGA4 | golgin A4 | 0.0352962 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0339939 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0334832 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0333775 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0329837 |
| SPAG9 | sperm associated antigen 9 | 0.0328244 |
| KRT17 | keratin 17, type I | 0.031539 |
| CANX | calnexin | 0.0304486 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0304474 |
| ARRDC3 | arrestin domain containing 3 | 0.0303216 |
| EFHD2 | EF-hand domain family, member D2 | 0.0299191 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.029657 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0284065 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0269823 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.026967 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0267739 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0264255 |
| MORF4L2 | mortality factor 4 like 2 | 0.0261567 |
| MSN | moesin | 0.0261115 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0260389 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0259497 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0259354 |
| MEF2A | myocyte enhancer factor 2A | 0.0259277 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0257318 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0254813 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0254588 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0252136 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0249062 |
| RNF19B | ring finger protein 19B | 0.0247848 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0247797 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.024727 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0247246 |
| CUL4B | cullin 4B | 0.0246015 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0245246 |
| SLK | STE20-like kinase | 0.0244861 |
| IRS2 | insulin receptor substrate 2 | 0.0243113 |
| SERINC3 | serine incorporator 3 | 0.0239559 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0239081 |
| WASF2 | WAS protein family, member 2 | 0.0238753 |
| SET | SET nuclear proto-oncogene | 0.0237783 |
| YBX3 | Y box binding protein 3 | 0.0235224 |
| SBF2 | SET binding factor 2 | 0.0235149 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0234961 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0233692 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0230685 |
| YAP1 | Yes-associated protein 1 | 0.0229843 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0229415 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0225978 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0224783 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0224056 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0219814 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0218812 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0217977 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.021744 |
| SUCO | SUN domain containing ossification factor | 0.0216428 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0214678 |
| KLF6 | Kruppel-like factor 6 | 0.0213352 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0212389 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0211056 |
| MCL1 | myeloid cell leukemia 1 | 0.0210219 |
| COG5 | component of oligomeric golgi complex 5 | 0.0210113 |
| CEP350 | centrosomal protein 350kDa | 0.0209341 |
| RPS6 | ribosomal protein S6 | 0.0208319 |
| TPR | translocated promoter region, nuclear basket protein | 0.0207802 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0207326 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.020727 |
| TPX2 | TPX2, microtubule-associated | 0.0206948 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0206546 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0205767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.145394 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0807524 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0651128 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0610897 |
| PODXL | podocalyxin-like | -0.0589756 |
| SULF1 | sulfatase 1 | -0.054855 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0481231 |
| SLC35F3 | solute carrier family 35, member F3 | -0.043918 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0403656 |
| ASPH | aspartate beta-hydroxylase | -0.0385094 |
| AOPEP | aminopeptidase O (putative) | -0.0375338 |
| FOXO1 | forkhead box O1 | -0.0346781 |
| LAMA5 | laminin, alpha 5 | -0.0327494 |
| MECOM | MDS1 and EVI1 complex locus | -0.0326377 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0324574 |
| PALLD | palladin, cytoskeletal associated protein | -0.0308097 |
| NRG1 | neuregulin 1 | -0.0287952 |
| FOXP1 | forkhead box P1 | -0.028004 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0277766 |
| SULF2 | sulfatase 2 | -0.0277209 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0271841 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.026444 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0262825 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0253822 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0250893 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0250834 |
| INTS6 | integrator complex subunit 6 | -0.0248445 |
| FLNA | filamin A, alpha | -0.024724 |
| RIGI | RNA sensor RIG-I | -0.0243237 |
| RCOR1 | REST corepressor 1 | -0.024218 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0242139 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0220527 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0213879 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.021177 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0211089 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0210936 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.020963 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0208444 |
| NEK7 | NIMA-related kinase 7 | -0.0208118 |
| EGFR | epidermal growth factor receptor | -0.0204991 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0203346 |
| DNAJC18 | DnaJ (Hsp40) homolog, subfamily C, member 18 | -0.0200655 |
| MTAP | methylthioadenosine phosphorylase | -0.0200254 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0199447 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0199347 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0197663 |
| DOK5 | docking protein 5 | -0.019314 |
| PLEC | plectin | -0.0193028 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0191735 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0189001 |
| MYO10 | myosin X | -0.0187809 |
| DST | dystonin | -0.0187457 |
| MEIS2 | Meis homeobox 2 | -0.0182119 |
| AFAP1L2 | actin filament associated protein 1-like 2 | -0.0181843 |
| RAD51B | RAD51 paralog B | -0.0180705 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0179992 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0178095 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0177986 |
| KIAA1671 | KIAA1671 | -0.0177264 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0176927 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0176379 |
| CORO2A | coronin, actin binding protein, 2A | -0.0176086 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0175037 |
| ACTN1 | actinin, alpha 1 | -0.0173748 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0172249 |
| EXOC6B | exocyst complex component 6B | -0.0171988 |
| ARHGAP23 | Rho GTPase activating protein 23 | -0.0170903 |
| AMOTL1 | angiomotin like 1 | -0.0169529 |
| AGMO | alkylglycerol monooxygenase | -0.0168937 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0167606 |
| DUSP4 | dual specificity phosphatase 4 | -0.0167363 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0166542 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.016629 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0164173 |
| BLCAP | bladder cancer associated protein | -0.0164141 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0164081 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0163486 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0161372 |
| RASAL2 | RAS protein activator like 2 | -0.0160297 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0159165 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0156857 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0156794 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.01563 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0155852 |
| FLNB | filamin B, beta | -0.0155144 |
| RHOJ | ras homolog family member J | -0.0154768 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0153011 |
| CTBP2 | C-terminal binding protein 2 | -0.0152467 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0151487 |
| RNF217 | ring finger protein 217 | -0.0151363 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0149538 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0148426 |
| PLXNA2 | plexin A2 | -0.014704 |
| HDAC9 | histone deacetylase 9 | -0.0146355 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0145179 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0145102 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0145097 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0144756 |
| KLF12 | Kruppel-like factor 12 | -0.0139638 |
| SP100 | SP100 nuclear antigen | -0.0138469 |
