| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP13A3 | ATPase type 13A3 | 0.11638 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0857985 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0788105 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0664361 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0563189 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0491224 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0478589 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0475564 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0469366 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0433033 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0422119 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0417682 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0403137 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0387188 |
| ZNF841 | zinc finger protein 841 | 0.0386883 |
| ANXA1 | annexin A1 | 0.0381868 |
| MT1X | metallothionein 1X | 0.0381622 |
| NUP153 | nucleoporin 153kDa | 0.0359938 |
| CANX | calnexin | 0.0359203 |
| IL6ST | interleukin 6 signal transducer | 0.0339628 |
| RBM39 | RNA binding motif protein 39 | 0.0336869 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0315901 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0311148 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0302241 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0299187 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.029858 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0296923 |
| PDS5B | PDS5 cohesin associated factor B | 0.0289436 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0286478 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0286097 |
| SPAG9 | sperm associated antigen 9 | 0.0277429 |
| DENND4C | DENN/MADD domain containing 4C | 0.0275298 |
| TNPO1 | transportin 1 | 0.0272781 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0271353 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0270523 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.026921 |
| TPD52 | tumor protein D52 | 0.0268743 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0268319 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0267445 |
| TXNRD1 | thioredoxin reductase 1 | 0.026717 |
| ZNF292 | zinc finger protein 292 | 0.0267155 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.026689 |
| GMPS | guanine monphosphate synthase | 0.0266182 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0265854 |
| GOLGA4 | golgin A4 | 0.0264116 |
| MMP12 | matrix metallopeptidase 12 | 0.0261934 |
| HLTF | helicase-like transcription factor | 0.0261446 |
| TFG | TRK-fused gene | 0.025779 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0250381 |
| IPO7 | importin 7 | 0.0248733 |
| TMEM41B | transmembrane protein 41B | 0.0246733 |
| CUL4B | cullin 4B | 0.0240186 |
| SNX4 | sorting nexin 4 | 0.0239951 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0238414 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0236318 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0232068 |
| ECT2 | epithelial cell transforming 2 | 0.022483 |
| ARF4 | ADP-ribosylation factor 4 | 0.0221883 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0220718 |
| NCKAP1 | NCK-associated protein 1 | 0.0215735 |
| SRP54 | signal recognition particle 54kDa | 0.0214272 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0211756 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0211172 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0210444 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0208608 |
| ANKRD28 | ankyrin repeat domain 28 | 0.02075 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0206545 |
| UBQLN1 | ubiquilin 1 | 0.0206483 |
| SUCO | SUN domain containing ossification factor | 0.0205762 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0204986 |
| ANXA5 | annexin A5 | 0.0204727 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0201658 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0201076 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0200963 |
| HELZ | helicase with zinc finger | 0.0198752 |
| NOP58 | NOP58 ribonucleoprotein | 0.0198609 |
| WRN | Werner syndrome, RecQ helicase-like | 0.019732 |
| NUP58 | nucleoporin 58 | 0.0195905 |
| AHNAK | AHNAK nucleoprotein | 0.0194521 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0192658 |
| NEK7 | NIMA-related kinase 7 | 0.0190756 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.019063 |
| TMEM39A | transmembrane protein 39A | 0.0190393 |
| TMSB4X | thymosin beta 4, X-linked | 0.0187539 |
| LNPK | lunapark, ER junction formation factor | 0.0187182 |
| WTAP | Wilms tumor 1 associated protein | 0.0186844 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0186427 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.018588 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.018582 |
| ARRDC3 | arrestin domain containing 3 | 0.0185639 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.018533 |
| PDE10A | phosphodiesterase 10A | 0.0184444 |
| ANLN | anillin, actin binding protein | 0.0183977 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0183112 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0182005 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0180469 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0179563 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0179321 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0179092 |
| CLTC | clathrin, heavy chain (Hc) | 0.0177823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.215855 |
| FTL | ferritin, light polypeptide | -0.199112 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.156151 |
| MT2A | metallothionein 2A | -0.15388 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.151374 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147733 |
| RPL35A | ribosomal protein L35a | -0.105829 |
| TMSB10 | thymosin beta 10 | -0.100168 |
| VIM | vimentin | -0.0968556 |
| RPS6 | ribosomal protein S6 | -0.091221 |
| FN1 | fibronectin 1 | -0.0875112 |
| NDRG1 | N-myc downstream regulated 1 | -0.0836465 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0819231 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0701268 |
| ACTG1 | actin gamma 1 | -0.0699786 |
| POTEF | POTE ankyrin domain family, member F | -0.069841 |
| INTS6 | integrator complex subunit 6 | -0.0690916 |
| RPLP2 | ribosomal protein, large, P2 | -0.0679528 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0671831 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0648757 |
| HLA-A | major histocompatibility complex, class I, A | -0.0623461 |
| PKM | pyruvate kinase, muscle | -0.0604422 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0575058 |
| PTMA | prothymosin, alpha | -0.0554775 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0539725 |
| RPS8 | ribosomal protein S8 | -0.0517919 |
| RPS3 | ribosomal protein S3 | -0.0476717 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0465758 |
| TPM1 | tropomyosin 1 (alpha) | -0.0459508 |
| TLE4 | transducin-like enhancer of split 4 | -0.0452317 |
| RPS13 | ribosomal protein S13 | -0.0450919 |
| RPLP1 | ribosomal protein, large, P1 | -0.0447821 |
| MAP1B | microtubule-associated protein 1B | -0.0436743 |
| S100A10 | S100 calcium binding protein A10 | -0.0432341 |
| PODXL | podocalyxin-like | -0.0429225 |
| RPL37 | ribosomal protein L37 | -0.0426835 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0424496 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0413014 |
| RPL31 | ribosomal protein L31 | -0.0407891 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0405698 |
| RPS19 | ribosomal protein S19 | -0.0403186 |
| RPL23 | ribosomal protein L23 | -0.0401613 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0396612 |
| ENO1 | enolase 1, (alpha) | -0.0390609 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0387277 |
| RPL37A | ribosomal protein L37a | -0.0382236 |
| GNAS | GNAS complex locus | -0.0382047 |
| CAVIN1 | caveolae associated protein 1 | -0.0373554 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0365343 |
| RPL5 | ribosomal protein L5 | -0.0363118 |
| ASPH | aspartate beta-hydroxylase | -0.0363045 |
| HMGA1 | high mobility group AT-hook 1 | -0.03626 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0360602 |
| RPL28 | ribosomal protein L28 | -0.0352823 |
| RPL11 | ribosomal protein L11 | -0.0347458 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0343234 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0341989 |
| VCL | vinculin | -0.034101 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.034026 |
| S100A6 | S100 calcium binding protein A6 | -0.0329791 |
| RPS23 | ribosomal protein S23 | -0.0319868 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0318653 |
| PFN1 | profilin 1 | -0.0316133 |
| NAV1 | neuron navigator 1 | -0.0314368 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0312584 |
| RPS24 | ribosomal protein S24 | -0.0312216 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0309999 |
| NAV2 | neuron navigator 2 | -0.0308539 |
| RPS17 | ribosomal protein S17 | -0.0304919 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0299103 |
| RPL7A | ribosomal protein L7a | -0.0298807 |
| RPS25 | ribosomal protein S25 | -0.0297702 |
| COL5A1 | collagen, type V, alpha 1 | -0.0297695 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0296884 |
| RPS29 | ribosomal protein S29 | -0.029609 |
| RACK1 | receptor for activated C kinase 1 | -0.0293543 |
| RPL27A | ribosomal protein L27a | -0.0289718 |
| CENPF | centromere protein F, 350/400kDa | -0.0286506 |
| RPS21 | ribosomal protein S21 | -0.0284236 |
| HMGB1 | high mobility group box 1 | -0.0283056 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0277538 |
| PLSCR1 | phospholipid scramblase 1 | -0.0275625 |
| FLNA | filamin A, alpha | -0.0275335 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0268364 |
| RPL34 | ribosomal protein L34 | -0.0268355 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0268295 |
| RIGI | RNA sensor RIG-I | -0.0267884 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0262214 |
| RPS20 | ribosomal protein S20 | -0.0261298 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0260303 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0258319 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0257942 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.025764 |
| RPL7 | ribosomal protein L7 | -0.0257337 |
| RPS27A | ribosomal protein S27a | -0.0256704 |
| RPS16 | ribosomal protein S16 | -0.0255576 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0253884 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0253675 |
| SEPTIN9 | septin 9 | -0.025095 |
| ANXA2 | annexin A2 | -0.0250902 |
