| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.267293 |
| DTNA | dystrobrevin, alpha | 0.112261 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.109864 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.109488 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0850725 |
| NUP58 | nucleoporin 58 | 0.0783949 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0772081 |
| SPAG9 | sperm associated antigen 9 | 0.0726165 |
| MMP12 | matrix metallopeptidase 12 | 0.0716124 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0676472 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0566097 |
| CD109 | CD109 molecule | 0.0563457 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0555649 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0528567 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0511021 |
| USP34 | ubiquitin specific peptidase 34 | 0.0497834 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0491965 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0459105 |
| TPM3 | tropomyosin 3 | 0.0439661 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0437094 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0431125 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0428573 |
| MED13L | mediator complex subunit 13-like | 0.0425636 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0418119 |
| PTK2 | protein tyrosine kinase 2 | 0.0416912 |
| ATP13A3 | ATPase type 13A3 | 0.0416343 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0410974 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0396545 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.039103 |
| FMNL2 | formin-like 2 | 0.0384621 |
| PHIP | pleckstrin homology domain interacting protein | 0.0367897 |
| WDR43 | WD repeat domain 43 | 0.0366474 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0356128 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0353404 |
| TXNIP | thioredoxin interacting protein | 0.0353094 |
| DST | dystonin | 0.0351224 |
| RNF145 | ring finger protein 145 | 0.0343399 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0336262 |
| MSN | moesin | 0.0335392 |
| KIF5B | kinesin family member 5B | 0.0330596 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0330113 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.032193 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0319042 |
| PGK1 | phosphoglycerate kinase 1 | 0.0317896 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0313662 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0313442 |
| SET | SET nuclear proto-oncogene | 0.031282 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0310435 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.030498 |
| TNPO1 | transportin 1 | 0.0302114 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0292714 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0284435 |
| RBM25 | RNA binding motif protein 25 | 0.0283268 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0282307 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.028152 |
| ASPH | aspartate beta-hydroxylase | 0.0278721 |
| ZNF638 | zinc finger protein 638 | 0.0278145 |
| TPM4 | tropomyosin 4 | 0.0277995 |
| PTMA | prothymosin, alpha | 0.0276547 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0273228 |
| HELZ | helicase with zinc finger | 0.0270303 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0269624 |
| NCKAP1 | NCK-associated protein 1 | 0.0268014 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0267318 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0264124 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0263505 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0259461 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0258368 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0256674 |
| FN1 | fibronectin 1 | 0.0254228 |
| RND3 | Rho family GTPase 3 | 0.0253788 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0247964 |
| JMJD1C | jumonji domain containing 1C | 0.0246483 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.024495 |
| CCNL1 | cyclin L1 | 0.0243557 |
| QKI | QKI, KH domain containing, RNA binding | 0.0242186 |
| MYO6 | myosin VI | 0.0239387 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0236763 |
| MED13 | mediator complex subunit 13 | 0.0234309 |
| DDHD1 | DDHD domain containing 1 | 0.0233031 |
| YBX3 | Y box binding protein 3 | 0.0231498 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0230498 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0230356 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0229534 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0228378 |
| ITGA6 | integrin, alpha 6 | 0.0227032 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0225138 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0223151 |
| PCNX1 | pecanex 1 | 0.0222091 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0221839 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0221033 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0220101 |
| NBAS | neuroblastoma amplified sequence | 0.021909 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0219026 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0218996 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0217643 |
| WDR45B | WD repeat domain 45B | 0.0214156 |
| USP3 | ubiquitin specific peptidase 3 | 0.0213821 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0212742 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0211512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.208326 |
| TMSB10 | thymosin beta 10 | -0.0867078 |
| ACTG1 | actin gamma 1 | -0.0825414 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0629123 |
| FTL | ferritin, light polypeptide | -0.0567798 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0545564 |
| RPL23 | ribosomal protein L23 | -0.0540307 |
| OSMR | oncostatin M receptor | -0.0457277 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439417 |
| RPLP1 | ribosomal protein, large, P1 | -0.0438897 |
| VIM | vimentin | -0.0433895 |
| FLNA | filamin A, alpha | -0.0429047 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0416561 |
| RPL12 | ribosomal protein L12 | -0.0410973 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0407656 |
| RPL26 | ribosomal protein L26 | -0.0382489 |
| CAVIN1 | caveolae associated protein 1 | -0.0368221 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0364932 |
| RPL35A | ribosomal protein L35a | -0.0362161 |
| RPS6 | ribosomal protein S6 | -0.0354901 |
| VCL | vinculin | -0.0352107 |
| CD44 | CD44 molecule (Indian blood group) | -0.0339215 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0332107 |
| SMAD3 | SMAD family member 3 | -0.0327802 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0321189 |
| RPL37A | ribosomal protein L37a | -0.0319587 |
| PTCHD4 | patched domain containing 4 | -0.0316109 |
| NDRG1 | N-myc downstream regulated 1 | -0.0314088 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0313053 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0311143 |
| RPS24 | ribosomal protein S24 | -0.0307878 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0306184 |
| RPLP0 | ribosomal protein, large, P0 | -0.0305595 |
| GPC6 | glypican 6 | -0.0300483 |
| PCDH11X | protocadherin 11 X-linked | -0.0297473 |
| RPL30 | ribosomal protein L30 | -0.0287014 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0285795 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0282009 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0278578 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0275861 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0273327 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0271233 |
| RPL36 | ribosomal protein L36 | -0.0264382 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0263009 |
| RACK1 | receptor for activated C kinase 1 | -0.025819 |
| TNNC1 | troponin C type 1 (slow) | -0.0256182 |
| RPL13A | ribosomal protein L13a | -0.0250474 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.024736 |
| PLEC | plectin | -0.0244692 |
| RNF213 | ring finger protein 213 | -0.0242819 |
| ERBIN | erbb2 interacting protein | -0.0241461 |
| RUNX1 | runt-related transcription factor 1 | -0.023932 |
| LSAMP | limbic system-associated membrane protein | -0.0238115 |
| MAP1B | microtubule-associated protein 1B | -0.0235477 |
| RIGI | RNA sensor RIG-I | -0.0235031 |
| NLGN1 | neuroligin 1 | -0.023166 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.022853 |
| FRMD6 | FERM domain containing 6 | -0.0227816 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0224381 |
| RPS19 | ribosomal protein S19 | -0.0224239 |
| RPS20 | ribosomal protein S20 | -0.0222986 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0221009 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0220319 |
| FOXP1 | forkhead box P1 | -0.0219475 |
| ACTN1 | actinin, alpha 1 | -0.0209956 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0207529 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0205628 |
| CALD1 | caldesmon 1 | -0.0205561 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0205204 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0205025 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0201919 |
| ETV6 | ets variant 6 | -0.0201486 |
| RPL38 | ribosomal protein L38 | -0.0200242 |
| ALPK2 | alpha-kinase 2 | -0.0197286 |
| PMP22 | peripheral myelin protein 22 | -0.01966 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0195962 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0193874 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0191131 |
| RPL27A | ribosomal protein L27a | -0.0186144 |
| RPS16 | ribosomal protein S16 | -0.0184679 |
| RPS8 | ribosomal protein S8 | -0.0184385 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0183794 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.018178 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0181765 |
| SP100 | SP100 nuclear antigen | -0.0181141 |
| TENM2 | teneurin transmembrane protein 2 | -0.0179533 |
| RPS14 | ribosomal protein S14 | -0.0179439 |
| CCDC91 | coiled-coil domain containing 91 | -0.0178359 |
| PRELID2 | PRELI domain containing 2 | -0.0177793 |
| ATG7 | autophagy related 7 | -0.0176466 |
| EGFR | epidermal growth factor receptor | -0.0172386 |
| NTM | neurotrimin | -0.0172178 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.017161 |
| RPL9 | ribosomal protein L9 | -0.0171294 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0171118 |
| PKM | pyruvate kinase, muscle | -0.0167497 |
| HMGA1 | high mobility group AT-hook 1 | -0.0167086 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0166232 |
| LATS2 | large tumor suppressor kinase 2 | -0.0164936 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.016482 |
