| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0858607 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0786663 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.077404 |
| TXNIP | thioredoxin interacting protein | 0.0755388 |
| ITGA6 | integrin, alpha 6 | 0.072443 |
| AREG | amphiregulin | 0.0556196 |
| DSPP | dentin sialophosphoprotein | 0.0514026 |
| FAT1 | FAT atypical cadherin 1 | 0.049176 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0462647 |
| LMO7 | LIM domain 7 | 0.0457104 |
| PTMA | prothymosin, alpha | 0.0416088 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0407862 |
| KIF5B | kinesin family member 5B | 0.0386176 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.037439 |
| ASPH | aspartate beta-hydroxylase | 0.0373178 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.037063 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0358481 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0341231 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0332951 |
| TPM3 | tropomyosin 3 | 0.0332537 |
| RNF145 | ring finger protein 145 | 0.0317556 |
| EZR | ezrin | 0.0305608 |
| SET | SET nuclear proto-oncogene | 0.0298837 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293733 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0293165 |
| VEGFA | vascular endothelial growth factor A | 0.0290553 |
| PTEN | phosphatase and tensin homolog | 0.0289682 |
| MED13L | mediator complex subunit 13-like | 0.0289581 |
| ENO1 | enolase 1, (alpha) | 0.0288941 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0288923 |
| USP6NL | USP6 N-terminal like | 0.0284262 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0279946 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0278121 |
| EREG | epiregulin | 0.027394 |
| VMP1 | vacuole membrane protein 1 | 0.0272005 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0270641 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0265843 |
| GOLGA4 | golgin A4 | 0.0264307 |
| RPL4 | ribosomal protein L4 | 0.0263977 |
| FTL | ferritin, light polypeptide | 0.0262779 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0262035 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0258997 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0254353 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0252159 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0250278 |
| USP34 | ubiquitin specific peptidase 34 | 0.0249134 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0247986 |
| CD164 | CD164 molecule, sialomucin | 0.0247252 |
| EPCAM | epithelial cell adhesion molecule | 0.0246673 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.02461 |
| NCKAP1 | NCK-associated protein 1 | 0.0238017 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0237622 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0234303 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0233416 |
| PAPOLA | poly(A) polymerase alpha | 0.023206 |
| TPD52 | tumor protein D52 | 0.0230168 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0229417 |
| RBM39 | RNA binding motif protein 39 | 0.0229027 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0227928 |
| XPO1 | exportin 1 | 0.0227312 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0223387 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0219558 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0216253 |
| ECT2 | epithelial cell transforming 2 | 0.0215417 |
| CENPF | centromere protein F, 350/400kDa | 0.0213614 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0213188 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0212742 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0211367 |
| CCNL1 | cyclin L1 | 0.0206486 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0206286 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0202431 |
| ZNF638 | zinc finger protein 638 | 0.0202428 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0202235 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0202054 |
| SETD2 | SET domain containing 2 | 0.019988 |
| CLTC | clathrin, heavy chain (Hc) | 0.0198816 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0197097 |
| PDS5B | PDS5 cohesin associated factor B | 0.019687 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0196511 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.019318 |
| ZNF654 | zinc finger protein 654 | 0.0192908 |
| ATP13A3 | ATPase type 13A3 | 0.0191482 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0191428 |
| PDZD8 | PDZ domain containing 8 | 0.0187842 |
| FOXO1 | forkhead box O1 | 0.0187333 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0186987 |
| STAG2 | stromal antigen 2 | 0.0186879 |
| PNN | pinin, desmosome associated protein | 0.0185231 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0184563 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0181065 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.018054 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0180341 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0179068 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0178639 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0178284 |
| MED13 | mediator complex subunit 13 | 0.01769 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0173548 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0172398 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0171996 |
| INSIG1 | insulin induced gene 1 | 0.0170852 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.2373 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.229267 |
| TMSB10 | thymosin beta 10 | -0.0816514 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0749348 |
| NDRG1 | N-myc downstream regulated 1 | -0.072121 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0654592 |
| TNS4 | tensin 4 | -0.0632942 |
| NPSR1 | neuropeptide S receptor 1 | -0.0628916 |
| VCL | vinculin | -0.0626096 |
| ONECUT3 | one cut homeobox 3 | -0.054951 |
| LAMA4 | laminin, alpha 4 | -0.040423 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0400372 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0384592 |
| AGR2 | anterior gradient 2 | -0.037073 |
| PIGR | polymeric immunoglobulin receptor | -0.0370605 |
| RPS8 | ribosomal protein S8 | -0.0364138 |
| RPLP1 | ribosomal protein, large, P1 | -0.0353558 |
| ACTN4 | actinin, alpha 4 | -0.0348963 |
| ANXA2 | annexin A2 | -0.0347066 |
| RPS24 | ribosomal protein S24 | -0.0327803 |
| FHIT | fragile histidine triad | -0.0327767 |
| CALR | calreticulin | -0.032099 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305898 |
| PRSS3 | protease, serine, 3 | -0.0305729 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0304694 |
| RPS6 | ribosomal protein S6 | -0.0294648 |
| FLNB | filamin B, beta | -0.0294457 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0285594 |
| NEBL | nebulette | -0.0284447 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0282404 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0280352 |
| EGFR | epidermal growth factor receptor | -0.0279169 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0278848 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277618 |
| GPHN | gephyrin | -0.0272212 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0265508 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0261407 |
| PALLD | palladin, cytoskeletal associated protein | -0.0259908 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0257086 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0255936 |
| KRT8 | keratin 8, type II | -0.025095 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0250171 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0246791 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0246417 |
| RPL34 | ribosomal protein L34 | -0.0243225 |
| MYO1D | myosin ID | -0.0243219 |
| LAMB3 | laminin, beta 3 | -0.0241888 |
| RPS19 | ribosomal protein S19 | -0.0234975 |
| JUP | junction plakoglobin | -0.023466 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0234606 |
| CADPS | Ca++-dependent secretion activator | -0.023275 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.023142 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0227765 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.022618 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0225902 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0222857 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.022268 |
| CD44 | CD44 molecule (Indian blood group) | -0.0220984 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0216628 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0215596 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0212683 |
| RNF43 | ring finger protein 43 | -0.0212329 |
| CCND1 | cyclin D1 | -0.021047 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0208867 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0207443 |
| SEC24D | SEC24 family member D | -0.020087 |
| FHL2 | four and a half LIM domains 2 | -0.0199881 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0199148 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0199093 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0196498 |
| ITGB4 | integrin, beta 4 | -0.0196041 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0195219 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0193237 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0192257 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0191927 |
| NUCB2 | nucleobindin 2 | -0.0191169 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0190556 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0186745 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0186546 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0185804 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0185459 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0185328 |
| MTAP | methylthioadenosine phosphorylase | -0.0184211 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0183111 |
| POF1B | premature ovarian failure, 1B | -0.0182313 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0180248 |
| KIAA1217 | KIAA1217 | -0.0179643 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0179455 |
| MECOM | MDS1 and EVI1 complex locus | -0.0178839 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0177787 |
| S100A10 | S100 calcium binding protein A10 | -0.0176796 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0176292 |
| IER3 | immediate early response 3 | -0.0176258 |
| RPS21 | ribosomal protein S21 | -0.0175082 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0173081 |
| MAP4 | microtubule-associated protein 4 | -0.0171143 |
| EHBP1 | EH domain binding protein 1 | -0.0169768 |
| WDR1 | WD repeat domain 1 | -0.0169598 |
| RPL9 | ribosomal protein L9 | -0.016934 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0169288 |
