| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.207889 |
| TXNRD1 | thioredoxin reductase 1 | 0.109458 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.109091 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.108752 |
| SPAG9 | sperm associated antigen 9 | 0.0798542 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0765623 |
| CANX | calnexin | 0.0761928 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0736163 |
| AHNAK | AHNAK nucleoprotein | 0.0694073 |
| RAI1 | retinoic acid induced 1 | 0.0661248 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0622038 |
| EZR | ezrin | 0.0615309 |
| TMSB4X | thymosin beta 4, X-linked | 0.0540794 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0504884 |
| CENPF | centromere protein F, 350/400kDa | 0.0474554 |
| SET | SET nuclear proto-oncogene | 0.0463584 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0435633 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0415659 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0408008 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0405113 |
| EREG | epiregulin | 0.0398645 |
| JMJD1C | jumonji domain containing 1C | 0.0397548 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0390884 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0386885 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0382891 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0379887 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0374151 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0372252 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0368373 |
| HDLBP | high density lipoprotein binding protein | 0.0360567 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0347872 |
| OGA | O-GlcNAcase | 0.034264 |
| XPO1 | exportin 1 | 0.0341507 |
| ANLN | anillin, actin binding protein | 0.0333202 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0333112 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0332879 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0327804 |
| FNIP1 | folliculin interacting protein 1 | 0.032125 |
| TXNIP | thioredoxin interacting protein | 0.0320802 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0318098 |
| ARRDC3 | arrestin domain containing 3 | 0.0316329 |
| TOP1 | topoisomerase (DNA) I | 0.031579 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0313226 |
| NUP58 | nucleoporin 58 | 0.0309138 |
| PGK1 | phosphoglycerate kinase 1 | 0.0308942 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0307648 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0305077 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0305005 |
| TMEM41B | transmembrane protein 41B | 0.029961 |
| PLK2 | polo-like kinase 2 | 0.0298682 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296384 |
| USP34 | ubiquitin specific peptidase 34 | 0.0295243 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0294536 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0291905 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0285224 |
| TPM3 | tropomyosin 3 | 0.0280983 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0279168 |
| KIF5B | kinesin family member 5B | 0.0270824 |
| CLTC | clathrin, heavy chain (Hc) | 0.0270357 |
| TAOK1 | TAO kinase 1 | 0.0268786 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0267043 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0265738 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0264596 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0258551 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0256087 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0255896 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0255504 |
| ANXA1 | annexin A1 | 0.0255456 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0254862 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0248308 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0245571 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0244934 |
| MKI67 | marker of proliferation Ki-67 | 0.02442 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0244081 |
| STAG2 | stromal antigen 2 | 0.024163 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0240888 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0235767 |
| IPO7 | importin 7 | 0.023345 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0233194 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0232731 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0231889 |
| WDR43 | WD repeat domain 43 | 0.0228282 |
| SBF2 | SET binding factor 2 | 0.0226502 |
| MATR3 | matrin 3 | 0.0223746 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0222658 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0221243 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0218929 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0218825 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0218638 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0217643 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0216066 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0215088 |
| ATP13A3 | ATPase type 13A3 | 0.0212753 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0211118 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0211024 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0208667 |
| YME1L1 | YME1-like 1 ATPase | 0.0208563 |
| TNPO1 | transportin 1 | 0.0208026 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0208015 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0205656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.249232 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218295 |
| VIM | vimentin | -0.163389 |
| TMSB10 | thymosin beta 10 | -0.146791 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.119947 |
| TP63 | tumor protein p63 | -0.113332 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0830954 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0809721 |
| FTL | ferritin, light polypeptide | -0.0704678 |
| RPL35A | ribosomal protein L35a | -0.0678513 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0645221 |
| RPL23 | ribosomal protein L23 | -0.0618196 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0612215 |
| HMGA1 | high mobility group AT-hook 1 | -0.0602301 |
| CD44 | CD44 molecule (Indian blood group) | -0.0572388 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0544067 |
| RIGI | RNA sensor RIG-I | -0.0542436 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0523642 |
| MT1E | metallothionein 1E | -0.0516714 |
| HLA-B | major histocompatibility complex, class I, B | -0.0512302 |
| CADM2 | cell adhesion molecule 2 | -0.0500593 |
| RPS19 | ribosomal protein S19 | -0.0482943 |
| SP100 | SP100 nuclear antigen | -0.0481498 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0474086 |
| RPS6 | ribosomal protein S6 | -0.0424004 |
| RPLP1 | ribosomal protein, large, P1 | -0.0419123 |
| RPS8 | ribosomal protein S8 | -0.0405979 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0396689 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0394788 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0388807 |
| RPL28 | ribosomal protein L28 | -0.0385259 |
| POTEF | POTE ankyrin domain family, member F | -0.0385048 |
| RPLP2 | ribosomal protein, large, P2 | -0.038474 |
| PLSCR1 | phospholipid scramblase 1 | -0.0378824 |
| RPL31 | ribosomal protein L31 | -0.0367156 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0355856 |
| RNF213 | ring finger protein 213 | -0.0354712 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0349378 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0340815 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0337373 |
| PODXL | podocalyxin-like | -0.033498 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0331539 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0329771 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0320994 |
| RPL36 | ribosomal protein L36 | -0.032028 |
| RPL19 | ribosomal protein L19 | -0.0309735 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0309428 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0306705 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0299291 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0292217 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0289824 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0288945 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0286837 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0286629 |
| TGM2 | transglutaminase 2 | -0.0283589 |
| RPS12 | ribosomal protein S12 | -0.0279927 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0275402 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0275291 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0273477 |
| RPL37A | ribosomal protein L37a | -0.0272592 |
| ACTG1 | actin gamma 1 | -0.0271488 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0270375 |
| RPL27 | ribosomal protein L27 | -0.0268433 |
| RPS10 | ribosomal protein S10 | -0.0266906 |
| MT1X | metallothionein 1X | -0.0262955 |
| RAD51B | RAD51 paralog B | -0.0261956 |
| PMP22 | peripheral myelin protein 22 | -0.0260782 |
| ANGPTL4 | angiopoietin-like 4 | -0.0260663 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0260658 |
| HLA-A | major histocompatibility complex, class I, A | -0.0259103 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0258856 |
| RPS29 | ribosomal protein S29 | -0.0253689 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0249566 |
| RPL26 | ribosomal protein L26 | -0.0249442 |
| RPL12 | ribosomal protein L12 | -0.0246647 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0245727 |
| RPS23 | ribosomal protein S23 | -0.0243027 |
| TRIM56 | tripartite motif containing 56 | -0.0241795 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0241374 |
| CMIP | c-Maf inducing protein | -0.0238676 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0234877 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0226854 |
| RPL34 | ribosomal protein L34 | -0.0226409 |
| PRDX1 | peroxiredoxin 1 | -0.0223092 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0221747 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.022 |
| RPS24 | ribosomal protein S24 | -0.0217693 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0215663 |
| ECE1 | endothelin converting enzyme 1 | -0.0214926 |
| S100A9 | S100 calcium binding protein A9 | -0.0213407 |
| RPL36A | ribosomal protein L36a | -0.021145 |
| S100A11 | S100 calcium binding protein A11 | -0.0211387 |
| RPL9 | ribosomal protein L9 | -0.021048 |
| RPL35 | ribosomal protein L35 | -0.0208913 |
| RPL38 | ribosomal protein L38 | -0.0208908 |
| RACK1 | receptor for activated C kinase 1 | -0.0207919 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.020557 |
| RPS17 | ribosomal protein S17 | -0.0204931 |
| SVIL | supervillin | -0.0201521 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0197704 |
