| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.13001 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.108138 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106984 |
| TXNRD1 | thioredoxin reductase 1 | 0.103452 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0964923 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0501892 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0500899 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0469264 |
| ENO1 | enolase 1, (alpha) | 0.0417753 |
| CANX | calnexin | 0.0374068 |
| AHNAK | AHNAK nucleoprotein | 0.0373667 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0373526 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0370185 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0342995 |
| JMJD1C | jumonji domain containing 1C | 0.0328914 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0306193 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0304918 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0281624 |
| USP34 | ubiquitin specific peptidase 34 | 0.0279538 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0274651 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0273992 |
| MKI67 | marker of proliferation Ki-67 | 0.0273885 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0272582 |
| IPO7 | importin 7 | 0.0271512 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0267627 |
| FMNL2 | formin-like 2 | 0.0266039 |
| CD164 | CD164 molecule, sialomucin | 0.0262699 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0261451 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0255722 |
| SPAG9 | sperm associated antigen 9 | 0.0253657 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0248992 |
| TPX2 | TPX2, microtubule-associated | 0.0248526 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0247604 |
| CCNL1 | cyclin L1 | 0.0243943 |
| KIF4A | kinesin family member 4A | 0.0238573 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0236916 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0234008 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0233683 |
| SERINC3 | serine incorporator 3 | 0.023109 |
| NGLY1 | N-glycanase 1 | 0.022799 |
| STAG2 | stromal antigen 2 | 0.0227933 |
| SET | SET nuclear proto-oncogene | 0.0224417 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0223087 |
| RPL4 | ribosomal protein L4 | 0.022174 |
| TPM3 | tropomyosin 3 | 0.0218025 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0216108 |
| PGK1 | phosphoglycerate kinase 1 | 0.021596 |
| ATXN2 | ataxin 2 | 0.0214435 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0211694 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0207997 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0206787 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0206727 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0201568 |
| TMPO | thymopoietin | 0.0201523 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0193259 |
| UBC | ubiquitin C | 0.0188012 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0185479 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.018384 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0181091 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.018075 |
| HELZ | helicase with zinc finger | 0.0177974 |
| PPME1 | protein phosphatase methylesterase 1 | 0.017576 |
| NCKAP1 | NCK-associated protein 1 | 0.017574 |
| HSPA4 | heat shock 70kDa protein 4 | 0.017556 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0175363 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0174676 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0172529 |
| ATP13A3 | ATPase type 13A3 | 0.0171436 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0170742 |
| TNPO1 | transportin 1 | 0.0170176 |
| HDGF | hepatoma-derived growth factor | 0.0168894 |
| WASHC4 | WASH complex subunit 4 | 0.0168619 |
| CPNE1 | copine I | 0.0167438 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0167436 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0166632 |
| FNIP1 | folliculin interacting protein 1 | 0.016658 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0166028 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.01654 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0165366 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0164828 |
| FOXO3 | forkhead box O3 | 0.0163996 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0163081 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0161989 |
| REV1 | REV1, polymerase (DNA directed) | 0.0161245 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0158772 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0157688 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0156987 |
| SGO2 | shugoshin 2 | 0.0156925 |
| SRPK2 | SRSF protein kinase 2 | 0.0156483 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0156463 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0155579 |
| STC1 | stanniocalcin 1 | 0.0155415 |
| ZNF638 | zinc finger protein 638 | 0.0155257 |
| MYPN | myopalladin | 0.0155115 |
| SEPTIN2 | septin 2 | 0.0153997 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0153756 |
| APP | amyloid beta (A4) precursor protein | 0.0153646 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.0152064 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0151887 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0151757 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150904 |
| TMSB10 | thymosin beta 10 | -0.0969582 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0597822 |
| RPL23 | ribosomal protein L23 | -0.0556151 |
| RAD51B | RAD51 paralog B | -0.0475812 |
| RPS21 | ribosomal protein S21 | -0.0452947 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0410679 |
| HLA-B | major histocompatibility complex, class I, B | -0.0388392 |
| PTMA | prothymosin, alpha | -0.038611 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0384908 |
| RPL35A | ribosomal protein L35a | -0.0383897 |
| OSMR | oncostatin M receptor | -0.0351967 |
| ACTG1 | actin gamma 1 | -0.0351918 |
| RPS8 | ribosomal protein S8 | -0.0351695 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.034386 |
| GNAS | GNAS complex locus | -0.0340214 |
| RPL37A | ribosomal protein L37a | -0.0338964 |
| RPL26 | ribosomal protein L26 | -0.0332665 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.032037 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.030861 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302037 |
| RPS12 | ribosomal protein S12 | -0.0296976 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.028999 |
| CUX1 | cut-like homeobox 1 | -0.0282252 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0280026 |
| VIM | vimentin | -0.0277805 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0272378 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0268291 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0267699 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0259578 |
| RNF213 | ring finger protein 213 | -0.0249001 |
| PKM | pyruvate kinase, muscle | -0.024049 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0238526 |
| NF1 | neurofibromin 1 | -0.0234758 |
| RPL9 | ribosomal protein L9 | -0.0230505 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0230426 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0229456 |
| PFN1 | profilin 1 | -0.0228677 |
| NEMF | nuclear export mediator factor | -0.0228656 |
| RPL34 | ribosomal protein L34 | -0.0224827 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0224512 |
| POTEF | POTE ankyrin domain family, member F | -0.0222542 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0221948 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0221463 |
| RPS29 | ribosomal protein S29 | -0.0217916 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0217361 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0214748 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0211739 |
| SSH2 | slingshot protein phosphatase 2 | -0.0208051 |
| HMGA1 | high mobility group AT-hook 1 | -0.0206662 |
| EHBP1 | EH domain binding protein 1 | -0.0206365 |
| RUNX1 | runt-related transcription factor 1 | -0.0205789 |
| EXOC4 | exocyst complex component 4 | -0.019904 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0197423 |
| WDR70 | WD repeat domain 70 | -0.0194396 |
| S100A10 | S100 calcium binding protein A10 | -0.0193864 |
| PDE10A | phosphodiesterase 10A | -0.0192891 |
| RPS10 | ribosomal protein S10 | -0.0192527 |
| PTMS | parathymosin | -0.0191671 |
| EGFR | epidermal growth factor receptor | -0.019079 |
| RPS4X | ribosomal protein S4, X-linked | -0.0190719 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0190041 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0187694 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0187112 |
| AGRN | agrin | -0.01861 |
| RPS20 | ribosomal protein S20 | -0.0186015 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0185643 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0185422 |
| FBXO11 | F-box protein 11 | -0.0185233 |
| ARMH4 | armadillo like helical domain containing 4 | -0.018516 |
| GRAMD1B | GRAM domain containing 1B | -0.0185092 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0183416 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0182732 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0181811 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | -0.0180964 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0177713 |
| WDR43 | WD repeat domain 43 | -0.0176576 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0173236 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0173074 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.017226 |
| CREBBP | CREB binding protein | -0.0172015 |
| MEF2D | myocyte enhancer factor 2D | -0.0171763 |
| ATF4 | activating transcription factor 4 | -0.017078 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0169391 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0167708 |
| TLK1 | tousled-like kinase 1 | -0.0165793 |
| ETV6 | ets variant 6 | -0.0165182 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0164322 |
| RPL27 | ribosomal protein L27 | -0.0163283 |
| RPS19 | ribosomal protein S19 | -0.0161757 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0161515 |
| FLNA | filamin A, alpha | -0.0161384 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -0.0160896 |
| RPS24 | ribosomal protein S24 | -0.0159709 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0159422 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0157732 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.01573 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0156914 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0155364 |
| SUMF1 | sulfatase modifying factor 1 | -0.0155261 |
