| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.044896 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0421497 |
| ZNF292 | zinc finger protein 292 | 0.0336074 |
| FAM168A | family with sequence similarity 168, member A | 0.032564 |
| COL3A1 | collagen, type III, alpha 1 | 0.0301863 |
| NCKAP1 | NCK-associated protein 1 | 0.0263107 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.026062 |
| ANXA5 | annexin A5 | 0.0250814 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0246156 |
| RIOK3 | RIO kinase 3 | 0.0243744 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0242879 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0241862 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0228059 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.022658 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0218908 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.021616 |
| SERINC3 | serine incorporator 3 | 0.0209629 |
| POSTN | periostin, osteoblast specific factor | 0.0199184 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0196176 |
| DENND4C | DENN/MADD domain containing 4C | 0.0189509 |
| FN1 | fibronectin 1 | 0.0187914 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.018739 |
| MEMO1 | mediator of cell motility 1 | 0.0185876 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0184333 |
| SPAG9 | sperm associated antigen 9 | 0.0182567 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0181422 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0180417 |
| RBM33 | RNA binding motif protein 33 | 0.0180218 |
| IL6ST | interleukin 6 signal transducer | 0.0179808 |
| KLF10 | Kruppel-like factor 10 | 0.0178996 |
| ZDBF2 | zinc finger, DBF-type containing 2 | 0.0176142 |
| DDHD2 | DDHD domain containing 2 | 0.017586 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0173884 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0172913 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0172431 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0171128 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0168198 |
| MED13L | mediator complex subunit 13-like | 0.0168125 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.016226 |
| HDAC9 | histone deacetylase 9 | 0.0161064 |
| AHNAK | AHNAK nucleoprotein | 0.0159076 |
| IPO7 | importin 7 | 0.0158947 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0158395 |
| YAP1 | Yes-associated protein 1 | 0.0156949 |
| RREB1 | ras responsive element binding protein 1 | 0.0154468 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0150461 |
| SDAD1 | SDA1 domain containing 1 | 0.0150155 |
| GAB2 | GRB2-associated binding protein 2 | 0.014787 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0147385 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0147226 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0146049 |
| HLTF | helicase-like transcription factor | 0.0145122 |
| RPS7 | ribosomal protein S7 | 0.0142471 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0142234 |
| WDR43 | WD repeat domain 43 | 0.0141309 |
| SSRP1 | structure specific recognition protein 1 | 0.0141308 |
| MB21D2 | Mab-21 domain containing 2 | 0.0140962 |
| PLPP6 | phospholipid phosphatase 6 | 0.0140249 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.0139283 |
| EFNA5 | ephrin-A5 | 0.0138799 |
| RUFY2 | RUN and FYVE domain containing 2 | 0.0138627 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.0137539 |
| UBXN7 | UBX domain protein 7 | 0.013751 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) | 0.0137426 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.0137364 |
| LPIN2 | lipin 2 | 0.013691 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0136571 |
| SIRT1 | sirtuin 1 | 0.0136467 |
| KIAA1328 | KIAA1328 | 0.0136345 |
| TAOK3 | TAO kinase 3 | 0.0136006 |
| RHOH | ras homolog family member H | 0.0135808 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0135269 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.0134457 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0133365 |
| SRSF2 | serine/arginine-rich splicing factor 2 | 0.0133185 |
| N4BP2 | NEDD4 binding protein 2 | 0.0132786 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0132761 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 0.0132139 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0132053 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0130829 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0129868 |
| ENTREP1 | endosomal transmembrane epsin interactor 1 | 0.0129428 |
| TIMELESS | timeless circadian clock | 0.0128773 |
| NRXN1 | neurexin 1 | 0.0127463 |
| TRAM1 | translocation associated membrane protein 1 | 0.0127293 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0127063 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 | 0.0126499 |
| TENM2 | teneurin transmembrane protein 2 | 0.0126014 |
| SETD5 | SET domain containing 5 | 0.0125802 |
| PTK2 | protein tyrosine kinase 2 | 0.0125792 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0124081 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0124024 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0123423 |
| EGFR | epidermal growth factor receptor | 0.0123414 |
| TGFB1 | transforming growth factor, beta 1 | 0.012303 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0121537 |
| FOXG1 | forkhead box G1 | 0.0121381 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0121102 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0120999 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0120645 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.173354 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.142302 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.122196 |
| COL11A1 | collagen, type XI, alpha 1 | -0.113493 |
| TMSB10 | thymosin beta 10 | -0.0998516 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0945367 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0914154 |
| ACTG1 | actin gamma 1 | -0.0791457 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0762309 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0700153 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0666477 |
| RPS6 | ribosomal protein S6 | -0.0628726 |
| PCDH9 | protocadherin 9 | -0.0620265 |
| ITGAV | integrin, alpha V | -0.0617521 |
| GNAS | GNAS complex locus | -0.0613923 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0602574 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0587027 |
| RPLP1 | ribosomal protein, large, P1 | -0.0574701 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0574576 |
| GOLGA4 | golgin A4 | -0.056452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0560642 |
| RPS8 | ribosomal protein S8 | -0.0555115 |
| RPS16 | ribosomal protein S16 | -0.0548783 |
| RPL11 | ribosomal protein L11 | -0.0544057 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0527302 |
| METAP2 | methionyl aminopeptidase 2 | -0.0524888 |
| TMSB4X | thymosin beta 4, X-linked | -0.0523285 |
| COL5A2 | collagen, type V, alpha 2 | -0.0513498 |
| FOXP2 | forkhead box P2 | -0.0512122 |
| TENM3 | teneurin transmembrane protein 3 | -0.0502491 |
| PLPP1 | phospholipid phosphatase 1 | -0.0494347 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0477897 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0468547 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0463691 |
| MEIS2 | Meis homeobox 2 | -0.0456204 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0443937 |
| LRRC4C | leucine rich repeat containing 4C | -0.0432649 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0423594 |
| RPL35A | ribosomal protein L35a | -0.0406255 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.040148 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0384575 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0381038 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0379307 |
| NEBL | nebulette | -0.0368251 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0366292 |
| YBX1 | Y box binding protein 1 | -0.0355953 |
| THBS1 | thrombospondin 1 | -0.0347684 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0345364 |
| PHIP | pleckstrin homology domain interacting protein | -0.0343424 |
| CDH19 | cadherin 19, type 2 | -0.0339246 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0338629 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0332441 |
| TJP1 | tight junction protein 1 | -0.0332073 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0330728 |
| CENPF | centromere protein F, 350/400kDa | -0.0328202 |
| NRG1 | neuregulin 1 | -0.0325914 |
| RPL37 | ribosomal protein L37 | -0.0325644 |
| SNX6 | sorting nexin 6 | -0.0324044 |
| BBX | bobby sox homolog (Drosophila) | -0.0323333 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0323225 |
| NOP58 | NOP58 ribonucleoprotein | -0.0322178 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0316828 |
| RPL19 | ribosomal protein L19 | -0.0314875 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0313453 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0312544 |
| RPS21 | ribosomal protein S21 | -0.0312419 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0312089 |
| SYT1 | synaptotagmin I | -0.0309555 |
| WDR70 | WD repeat domain 70 | -0.0307922 |
| TPR | translocated promoter region, nuclear basket protein | -0.0307181 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0303054 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0301665 |
| RLF | rearranged L-myc fusion | -0.0301281 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0300942 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0297235 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0297198 |
| RPS12 | ribosomal protein S12 | -0.0296569 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0293948 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.029387 |
| DEK | DEK proto-oncogene | -0.0292542 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0281956 |
| ANXA1 | annexin A1 | -0.0281676 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0281224 |
| ARF1 | ADP-ribosylation factor 1 | -0.0279559 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0276122 |
| FAM171B | family with sequence similarity 171, member B | -0.0274766 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.027434 |
| POU3F2 | POU class 3 homeobox 2 | -0.0274065 |
| TOP1 | topoisomerase (DNA) I | -0.027338 |
| HMGB1 | high mobility group box 1 | -0.0269628 |
| PFN1 | profilin 1 | -0.0268392 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0268372 |
| ANXA2 | annexin A2 | -0.0264584 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0262264 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0261936 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0261646 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0261079 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0260712 |
| NF1 | neurofibromin 1 | -0.0259825 |
| DPYD | dihydropyrimidine dehydrogenase | -0.02581 |
