| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.125298 |
| VCL | vinculin | 0.0697287 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0566554 |
| ZFP36 | ZFP36 ring finger protein | 0.0427897 |
| MT2A | metallothionein 2A | 0.0421699 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0415745 |
| TXNRD1 | thioredoxin reductase 1 | 0.038719 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0386842 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0308876 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0305817 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0300254 |
| IPO7 | importin 7 | 0.0299695 |
| VMP1 | vacuole membrane protein 1 | 0.0299178 |
| ATP13A3 | ATPase type 13A3 | 0.0288862 |
| INTS6 | integrator complex subunit 6 | 0.027792 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0274959 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0271326 |
| ARRDC3 | arrestin domain containing 3 | 0.0258476 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0257095 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0253492 |
| CCNL1 | cyclin L1 | 0.0252086 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0237498 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0237323 |
| EPAS1 | endothelial PAS domain protein 1 | 0.023389 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0231494 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0228385 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0219125 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0217995 |
| B2M | beta-2-microglobulin | 0.0217983 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0214456 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.021431 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.0212536 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0210451 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0208742 |
| TMEM41B | transmembrane protein 41B | 0.0205235 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0205099 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0204499 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0204161 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201313 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0197846 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0195138 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0189743 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0188237 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0184943 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0184019 |
| NUP98 | nucleoporin 98kDa | 0.0179845 |
| FKBP5 | FK506 binding protein 5 | 0.0175427 |
| ATF6 | activating transcription factor 6 | 0.0173798 |
| MCL1 | myeloid cell leukemia 1 | 0.0165273 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0163007 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0162014 |
| JAK1 | Janus kinase 1 | 0.0161075 |
| PERP | PERP, TP53 apoptosis effector | 0.0156719 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0154874 |
| TSC22D2 | TSC22 domain family, member 2 | 0.015485 |
| SUCO | SUN domain containing ossification factor | 0.0154697 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0154693 |
| ANLN | anillin, actin binding protein | 0.0154133 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0153922 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0152852 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0150475 |
| RNF145 | ring finger protein 145 | 0.0147163 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0145621 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0143416 |
| RPLP2 | ribosomal protein, large, P2 | 0.0143188 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0142644 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0141566 |
| USP15 | ubiquitin specific peptidase 15 | 0.0141159 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0140963 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0140152 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.014015 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0140034 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0139718 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0138301 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0138159 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0137852 |
| BMP6 | bone morphogenetic protein 6 | 0.0136971 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0136897 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0136224 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0135843 |
| SFTPA2 | surfactant protein A2 | 0.013497 |
| RPL37A | ribosomal protein L37a | 0.0133837 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.013375 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.0133408 |
| OGA | O-GlcNAcase | 0.0133184 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0130174 |
| SBF2 | SET binding factor 2 | 0.0129325 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0128991 |
| WDR43 | WD repeat domain 43 | 0.0127721 |
| DENND4A | DENN/MADD domain containing 4A | 0.0126916 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0126543 |
| MED13L | mediator complex subunit 13-like | 0.0125054 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0124972 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0124317 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.012428 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0123724 |
| FERMT2 | fermitin family member 2 | 0.0123135 |
| IMMT | inner membrane protein, mitochondrial | 0.0122518 |
| PTEN | phosphatase and tensin homolog | 0.0121848 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0121705 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.259363 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.203938 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.118084 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.112798 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0837986 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0815173 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.079083 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0768026 |
| RPS16 | ribosomal protein S16 | -0.0639598 |
| TMSB10 | thymosin beta 10 | -0.0633374 |
| MAP1B | microtubule-associated protein 1B | -0.0596539 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0565228 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0531609 |
| AFAP1 | actin filament associated protein 1 | -0.0512547 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0505336 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0491287 |
| PTMA | prothymosin, alpha | -0.0454449 |
| S100A6 | S100 calcium binding protein A6 | -0.0452662 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0437704 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0432183 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0429488 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0419698 |
| EHBP1 | EH domain binding protein 1 | -0.0390665 |
| RNF220 | ring finger protein 220 | -0.0389481 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0388629 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.03705 |
| MYO10 | myosin X | -0.0367705 |
| RIGI | RNA sensor RIG-I | -0.0361316 |
| SQSTM1 | sequestosome 1 | -0.0348776 |
| LDHA | lactate dehydrogenase A | -0.0345412 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0341439 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0332354 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0329467 |
| ATG7 | autophagy related 7 | -0.0321883 |
| TNS3 | tensin 3 | -0.0319303 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0313805 |
| CANX | calnexin | -0.0306913 |
| GNAS | GNAS complex locus | -0.0298119 |
| RIN2 | Ras and Rab interactor 2 | -0.0292826 |
| CD44 | CD44 molecule (Indian blood group) | -0.0289089 |
| RPLP1 | ribosomal protein, large, P1 | -0.0288711 |
| SMAD3 | SMAD family member 3 | -0.0287187 |
| LMNA | lamin A/C | -0.0281214 |
| PTK2 | protein tyrosine kinase 2 | -0.0277965 |
| MEF2A | myocyte enhancer factor 2A | -0.0277682 |
| NHSL1 | NHS-like 1 | -0.0276743 |
| ACTG1 | actin gamma 1 | -0.0269087 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.026788 |
| HMGA1 | high mobility group AT-hook 1 | -0.0264787 |
| H1-0 | H1.0 linker histone | -0.0257068 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0254729 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0253383 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0252807 |
| SYNJ2 | synaptojanin 2 | -0.0251015 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0250292 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.024164 |
| ANXA2 | annexin A2 | -0.0241589 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.024036 |
| MYOF | myoferlin | -0.0237627 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0233577 |
| FBXO27 | F-box protein 27 | -0.0233344 |
| TCF12 | transcription factor 12 | -0.0231524 |
| AHNAK | AHNAK nucleoprotein | -0.0223898 |
| RNF213 | ring finger protein 213 | -0.0223312 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0223244 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0221357 |
| CTSD | cathepsin D | -0.0220261 |
| CADM1 | cell adhesion molecule 1 | -0.0217287 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0216939 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0214324 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.020838 |
| EGFR | epidermal growth factor receptor | -0.0207141 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0207109 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0206863 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0200567 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0199846 |
| RPLP0 | ribosomal protein, large, P0 | -0.0197606 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0197113 |
| DIAPH2 | diaphanous-related formin 2 | -0.0195689 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0195627 |
| DST | dystonin | -0.0193835 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0193559 |
| KRT19 | keratin 19, type I | -0.0191782 |
| CD109 | CD109 molecule | -0.0190278 |
| APP | amyloid beta (A4) precursor protein | -0.0189841 |
| CUX1 | cut-like homeobox 1 | -0.0189782 |
| FANK1 | fibronectin type III and ankyrin repeat domains 1 | -0.018584 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0184503 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0184127 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0183811 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0183136 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0179188 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0177534 |
| TMEM123 | transmembrane protein 123 | -0.0177159 |
| SEPTIN7 | septin 7 | -0.0176872 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0176752 |
| PRSS23 | protease, serine, 23 | -0.0175776 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0175583 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0175218 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0173743 |
