| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.157617 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.140708 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.102449 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.100223 |
| EMP1 | epithelial membrane protein 1 | 0.0803588 |
| KRT7 | keratin 7, type II | 0.075513 |
| RPS6 | ribosomal protein S6 | 0.0739727 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0725307 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0723355 |
| MT2A | metallothionein 2A | 0.0705741 |
| MYO6 | myosin VI | 0.0704436 |
| CCNL1 | cyclin L1 | 0.0647395 |
| B2M | beta-2-microglobulin | 0.061754 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0617309 |
| EZR | ezrin | 0.0587702 |
| WWC1 | WW and C2 domain containing 1 | 0.0552152 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0543168 |
| RBM39 | RNA binding motif protein 39 | 0.0537123 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.053325 |
| LAMB3 | laminin, beta 3 | 0.0532177 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0522648 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0505143 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0504704 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0500519 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0493971 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0481631 |
| ARRDC3 | arrestin domain containing 3 | 0.0481557 |
| AFDN | afadin, adherens junction formation factor | 0.0467481 |
| ANXA2 | annexin A2 | 0.0466149 |
| RPS8 | ribosomal protein S8 | 0.0465803 |
| FAM3C | family with sequence similarity 3, member C | 0.0465484 |
| RYBP | RING1 and YY1 binding protein | 0.0462048 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0442565 |
| IRS2 | insulin receptor substrate 2 | 0.0436699 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0432796 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0431804 |
| TFRC | transferrin receptor | 0.0431424 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0425715 |
| RDX | radixin | 0.0422013 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0411376 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0409842 |
| TXNIP | thioredoxin interacting protein | 0.0391788 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0391507 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0386725 |
| POTEF | POTE ankyrin domain family, member F | 0.0379388 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0363817 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0362009 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.035366 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0349963 |
| CALR | calreticulin | 0.0344578 |
| RTN4 | reticulon 4 | 0.0343002 |
| BRD2 | bromodomain containing 2 | 0.034269 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.034025 |
| ANO6 | anoctamin 6 | 0.0338329 |
| OGA | O-GlcNAcase | 0.0334963 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0334832 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0333844 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0333527 |
| RPL12 | ribosomal protein L12 | 0.0332665 |
| ATP13A3 | ATPase type 13A3 | 0.0330198 |
| FMNL2 | formin-like 2 | 0.0329442 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.032745 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0325197 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0322184 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0318472 |
| SET | SET nuclear proto-oncogene | 0.0318374 |
| AHNAK | AHNAK nucleoprotein | 0.0313992 |
| IL6ST | interleukin 6 signal transducer | 0.0312731 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0310598 |
| DIAPH1 | diaphanous-related formin 1 | 0.0309858 |
| RPL37A | ribosomal protein L37a | 0.0309618 |
| RPS27A | ribosomal protein S27a | 0.0309066 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0308204 |
| TPM3 | tropomyosin 3 | 0.030637 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0305607 |
| ATP11B | ATPase, class VI, type 11B | 0.0305424 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0305293 |
| CAPRIN2 | caprin family member 2 | 0.0304775 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0304665 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0301885 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0299206 |
| RPS3 | ribosomal protein S3 | 0.0296985 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0295224 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0294967 |
| PTK2 | protein tyrosine kinase 2 | 0.0294639 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0294013 |
| RPL4 | ribosomal protein L4 | 0.0293644 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0292063 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0291315 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0290177 |
| YBX3 | Y box binding protein 3 | 0.0289165 |
| DSPP | dentin sialophosphoprotein | 0.0288133 |
| FKBP5 | FK506 binding protein 5 | 0.02867 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0284077 |
| RASA2 | RAS p21 protein activator 2 | 0.0281165 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0279617 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0278482 |
| SPAG9 | sperm associated antigen 9 | 0.0277812 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0276004 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0274264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.132665 |
| MUC4 | mucin 4, cell surface associated | -0.112578 |
| RNF213 | ring finger protein 213 | -0.0870441 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0861354 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0681823 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0666464 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0647059 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0637371 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0623985 |
| MUC16 | mucin 16, cell surface associated | -0.0622775 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0540853 |
| FN1 | fibronectin 1 | -0.0508651 |
| SMYD3 | SET and MYND domain containing 3 | -0.0508611 |
| CD2AP | CD2-associated protein | -0.0470623 |
| ASPH | aspartate beta-hydroxylase | -0.0467215 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0434074 |
| RBM47 | RNA binding motif protein 47 | -0.0431807 |
| EGFR | epidermal growth factor receptor | -0.0426395 |
| SVIL | supervillin | -0.0422286 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.041697 |
| ETV6 | ets variant 6 | -0.0373821 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0341398 |
| RUNX1 | runt-related transcription factor 1 | -0.0335702 |
| PLSCR1 | phospholipid scramblase 1 | -0.0332494 |
| DAPK1 | death-associated protein kinase 1 | -0.0330783 |
| RIGI | RNA sensor RIG-I | -0.0319817 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0319137 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0316483 |
| TMSB10 | thymosin beta 10 | -0.0308813 |
| MX2 | MX dynamin-like GTPase 2 | -0.0303024 |
| SULF2 | sulfatase 2 | -0.0298992 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0298583 |
| PCDH7 | protocadherin 7 | -0.0294728 |
| MX1 | MX dynamin-like GTPase 1 | -0.0294504 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0289313 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0285631 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0284995 |
| SSH2 | slingshot protein phosphatase 2 | -0.0280613 |
| EXOC4 | exocyst complex component 4 | -0.0277077 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0275828 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0268925 |
| VCL | vinculin | -0.0267622 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0267082 |
| KYNU | kynureninase | -0.026707 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0267011 |
| RRBP1 | ribosome binding protein 1 | -0.0266419 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.0264778 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.026468 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0261892 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0261752 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.026139 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0260219 |
| EHBP1 | EH domain binding protein 1 | -0.0259355 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0256279 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.025524 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0254616 |
| MECOM | MDS1 and EVI1 complex locus | -0.0254344 |
| FRMD5 | FERM domain containing 5 | -0.0253029 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0252889 |
| PDLIM5 | PDZ and LIM domain 5 | -0.025241 |
| TPI1 | triosephosphate isomerase 1 | -0.0249338 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0246903 |
| HLA-C | major histocompatibility complex, class I, C | -0.024485 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0241444 |
| LAMA4 | laminin, alpha 4 | -0.0240385 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0239485 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0236619 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0235335 |
| ANLN | anillin, actin binding protein | -0.0233707 |
| SYT14 | synaptotagmin XIV | -0.0232367 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0227421 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0227129 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0226377 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0226308 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0225876 |
| EGR1 | early growth response 1 | -0.0225572 |
| TCF12 | transcription factor 12 | -0.0224857 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0222661 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0222424 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0221387 |
| AOPEP | aminopeptidase O (putative) | -0.0220796 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0217533 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0216928 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0216476 |
| ACTN4 | actinin, alpha 4 | -0.0214579 |
| ZNF609 | zinc finger protein 609 | -0.0211393 |
| HLA-E | major histocompatibility complex, class I, E | -0.0210204 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0210075 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0207314 |
| RAD51B | RAD51 paralog B | -0.020679 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0205638 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.020371 |
| R3HDM2 | R3H domain containing 2 | -0.0202782 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0200809 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0198828 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0197997 |
| INVS | inversin | -0.0197042 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0194592 |
| H1-0 | H1.0 linker histone | -0.0193575 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0192945 |
