| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.170786 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0827435 |
| SET | SET nuclear proto-oncogene | 0.0675053 |
| JMJD1C | jumonji domain containing 1C | 0.064535 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0645258 |
| PGK1 | phosphoglycerate kinase 1 | 0.0644355 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.063496 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.058029 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0567423 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.054251 |
| HDAC9 | histone deacetylase 9 | 0.0538971 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0515586 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0514077 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.050678 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0502756 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0491612 |
| RBM39 | RNA binding motif protein 39 | 0.0470888 |
| ZNF292 | zinc finger protein 292 | 0.0440581 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0425996 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0420535 |
| NUP58 | nucleoporin 58 | 0.0415192 |
| HMGA2 | high mobility group AT-hook 2 | 0.0413272 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0411387 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0409787 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0406378 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.040613 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.040134 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0399129 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.039852 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0397942 |
| ANXA5 | annexin A5 | 0.039448 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0387016 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0386325 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0383187 |
| ATP13A3 | ATPase type 13A3 | 0.0379956 |
| FRMD6 | FERM domain containing 6 | 0.0379672 |
| ZNF207 | zinc finger protein 207 | 0.0377199 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0367632 |
| BBX | bobby sox homolog (Drosophila) | 0.0367357 |
| CORO1C | coronin, actin binding protein, 1C | 0.0366497 |
| FRMD4A | FERM domain containing 4A | 0.0363051 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0358883 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.035824 |
| TTR | transthyretin | 0.0357567 |
| WDR43 | WD repeat domain 43 | 0.0356681 |
| RTN4 | reticulon 4 | 0.0351461 |
| SBF2 | SET binding factor 2 | 0.0349901 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0346586 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0343505 |
| RPS2 | ribosomal protein S2 | 0.0337245 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0330264 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0322466 |
| CANX | calnexin | 0.0318557 |
| XPO1 | exportin 1 | 0.0317069 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316037 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0315512 |
| NAV3 | neuron navigator 3 | 0.0314432 |
| CCNL1 | cyclin L1 | 0.0314003 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0313977 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0309566 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0307719 |
| YTHDC1 | YTH domain containing 1 | 0.0302423 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0298762 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0298556 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0297967 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0296178 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0293954 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0292765 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0288441 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0288062 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0288051 |
| GOLGA4 | golgin A4 | 0.0281775 |
| MATR3 | matrin 3 | 0.0280214 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.027666 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0276479 |
| TEX10 | testis expressed 10 | 0.0276005 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0275483 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0274624 |
| NCKAP1 | NCK-associated protein 1 | 0.0274216 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0271274 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0271028 |
| ENO1 | enolase 1, (alpha) | 0.0270723 |
| MCL1 | myeloid cell leukemia 1 | 0.0269397 |
| CLTC | clathrin, heavy chain (Hc) | 0.0269355 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0268119 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0267962 |
| PCBP2 | poly(rC) binding protein 2 | 0.0267092 |
| UBXN7 | UBX domain protein 7 | 0.0266072 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0263532 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0263519 |
| DENND5A | DENN/MADD domain containing 5A | 0.0260138 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0259841 |
| OGA | O-GlcNAcase | 0.02596 |
| RYBP | RING1 and YY1 binding protein | 0.0257993 |
| MED13L | mediator complex subunit 13-like | 0.0256939 |
| DENND4A | DENN/MADD domain containing 4A | 0.0256566 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0255951 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.02552 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0254971 |
| FOXO3 | forkhead box O3 | 0.0252526 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.12207 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0495935 |
| RPS6 | ribosomal protein S6 | -0.0485791 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0468213 |
| RPLP0 | ribosomal protein, large, P0 | -0.0443487 |
| RPL35A | ribosomal protein L35a | -0.0436022 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0423407 |
| TMSB10 | thymosin beta 10 | -0.0407457 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0403464 |
| RPL23 | ribosomal protein L23 | -0.0390014 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.037245 |
| RPL8 | ribosomal protein L8 | -0.036465 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0357515 |
| PTMA | prothymosin, alpha | -0.0352992 |
| RPLP1 | ribosomal protein, large, P1 | -0.0334187 |
| RPLP2 | ribosomal protein, large, P2 | -0.0329564 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0313596 |
| RPS14 | ribosomal protein S14 | -0.0313591 |
| RPL26 | ribosomal protein L26 | -0.031333 |
| RPS24 | ribosomal protein S24 | -0.0309822 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0296696 |
| RPL34 | ribosomal protein L34 | -0.0290891 |
| RPL36 | ribosomal protein L36 | -0.0283519 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0282891 |
| RPL7 | ribosomal protein L7 | -0.0282618 |
| RPL9 | ribosomal protein L9 | -0.0272246 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0271192 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270121 |
| RAD51B | RAD51 paralog B | -0.0268744 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0263275 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0262483 |
| HMGA1 | high mobility group AT-hook 1 | -0.0261378 |
| ANXA2 | annexin A2 | -0.0261273 |
| RPS21 | ribosomal protein S21 | -0.025919 |
| RPL30 | ribosomal protein L30 | -0.0258811 |
| RPL35 | ribosomal protein L35 | -0.0257053 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0252884 |
| MTDH | metadherin | -0.023508 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.02305 |
| RPL36A | ribosomal protein L36a | -0.0224122 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.022026 |
| MX1 | MX dynamin-like GTPase 1 | -0.0219288 |
| RPS19 | ribosomal protein S19 | -0.0217972 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.021687 |
| FHL2 | four and a half LIM domains 2 | -0.0215617 |
| HMGB1 | high mobility group box 1 | -0.0214686 |
| RPS17 | ribosomal protein S17 | -0.0213286 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.0211489 |
| RPL12 | ribosomal protein L12 | -0.0208566 |
| RPL13A | ribosomal protein L13a | -0.0201367 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0200827 |
| GOLM2 | golgi membrane protein 2 | -0.0200296 |
| PFN1 | profilin 1 | -0.019936 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0198329 |
| RPL19 | ribosomal protein L19 | -0.01975 |
| POTEF | POTE ankyrin domain family, member F | -0.019539 |
| RPS15 | ribosomal protein S15 | -0.0194451 |
| S100A9 | S100 calcium binding protein A9 | -0.0191583 |
| EMP1 | epithelial membrane protein 1 | -0.0190677 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0188532 |
| FOXP1 | forkhead box P1 | -0.0188476 |
| RPS8 | ribosomal protein S8 | -0.0187097 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0186247 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0186023 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0184944 |
| GNAS | GNAS complex locus | -0.0184693 |
| TASP1 | taspase, threonine aspartase, 1 | -0.0182551 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0182425 |
| S100A6 | S100 calcium binding protein A6 | -0.0181372 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0179862 |
| TCF12 | transcription factor 12 | -0.0179337 |
| ARF1 | ADP-ribosylation factor 1 | -0.0178099 |
| ZNF438 | zinc finger protein 438 | -0.0174392 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0174357 |
| MTAP | methylthioadenosine phosphorylase | -0.0172633 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0170905 |
| TPX2 | TPX2, microtubule-associated | -0.0170027 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0169985 |
| S100A10 | S100 calcium binding protein A10 | -0.0169342 |
| CENPF | centromere protein F, 350/400kDa | -0.0168926 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0168472 |
| BPTF | bromodomain PHD finger transcription factor | -0.0166766 |
| WWOX | WW domain containing oxidoreductase | -0.0166456 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0165579 |
| PFDN5 | prefoldin subunit 5 | -0.0165402 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0164597 |
| RPL7A | ribosomal protein L7a | -0.0164337 |
| LDHB | lactate dehydrogenase B | -0.0164213 |
| DUSP6 | dual specificity phosphatase 6 | -0.0163414 |
| SFMBT1 | Scm-like with four mbt domains 1 | -0.0161432 |
| GPHN | gephyrin | -0.016085 |
| PHF14 | PHD finger protein 14 | -0.0160571 |
| RPS20 | ribosomal protein S20 | -0.016001 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0159098 |
| INVS | inversin | -0.0159055 |
| MAP4 | microtubule-associated protein 4 | -0.0158383 |
| RPS25 | ribosomal protein S25 | -0.0158201 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0157078 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0156441 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0155998 |
