| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.0842276 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0736776 |
| ZNF292 | zinc finger protein 292 | 0.0567483 |
| XPO1 | exportin 1 | 0.0550229 |
| NBAS | neuroblastoma amplified sequence | 0.0549269 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0512171 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0462765 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0450757 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0446383 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0424324 |
| GOLGA4 | golgin A4 | 0.0422636 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0417487 |
| SRP54 | signal recognition particle 54kDa | 0.0412151 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0411504 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0409453 |
| SBF2 | SET binding factor 2 | 0.0403798 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.040182 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.039675 |
| RPS2 | ribosomal protein S2 | 0.0391282 |
| CCNL1 | cyclin L1 | 0.0391109 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0388976 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0383577 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0366674 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.036603 |
| B2M | beta-2-microglobulin | 0.0360866 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0360354 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0358443 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0357831 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0356066 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0352084 |
| HELZ | helicase with zinc finger | 0.0351364 |
| NUP58 | nucleoporin 58 | 0.0347129 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0340799 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0339255 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0325566 |
| NCKAP1 | NCK-associated protein 1 | 0.0322999 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0318615 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0310648 |
| PDS5B | PDS5 cohesin associated factor B | 0.0310273 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0306511 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0296693 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0293987 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0289231 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0283453 |
| FAM13A | family with sequence similarity 13, member A | 0.0283249 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0280924 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0275245 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0274948 |
| RYBP | RING1 and YY1 binding protein | 0.0272564 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0260795 |
| ENO1 | enolase 1, (alpha) | 0.0260119 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.025735 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0257317 |
| MYOF | myoferlin | 0.0253379 |
| NGLY1 | N-glycanase 1 | 0.0253077 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0250248 |
| ITGAV | integrin, alpha V | 0.024917 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0246172 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0246126 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0245476 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.024362 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0240391 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0240169 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0240073 |
| INSIG2 | insulin induced gene 2 | 0.0239268 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0238541 |
| DENR | density-regulated protein | 0.0237927 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0237686 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0236521 |
| SET | SET nuclear proto-oncogene | 0.0236114 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0236052 |
| COPA | coatomer protein complex, subunit alpha | 0.0235716 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0234808 |
| DENND4A | DENN/MADD domain containing 4A | 0.0234007 |
| PHF21A | PHD finger protein 21A | 0.0233866 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0233779 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.023303 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0232904 |
| HDGF | hepatoma-derived growth factor | 0.0231963 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.022994 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.02296 |
| FNIP1 | folliculin interacting protein 1 | 0.0228514 |
| ATP13A3 | ATPase type 13A3 | 0.0227509 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0226995 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0226354 |
| ZNF638 | zinc finger protein 638 | 0.0224147 |
| SETD5 | SET domain containing 5 | 0.0223665 |
| OGA | O-GlcNAcase | 0.0223267 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.022244 |
| COG6 | component of oligomeric golgi complex 6 | 0.0220127 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0219566 |
| PCM1 | pericentriolar material 1 | 0.0219053 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0216463 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0216463 |
| PGK1 | phosphoglycerate kinase 1 | 0.0214845 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0214528 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0214242 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0214197 |
| ZNF451 | zinc finger protein 451 | 0.0212862 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0211051 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152701 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.152319 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.113287 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.111216 |
| PTMA | prothymosin, alpha | -0.108157 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0873 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0822634 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0821001 |
| FOXP1 | forkhead box P1 | -0.0795899 |
| ACTG1 | actin gamma 1 | -0.0743879 |
| AHNAK | AHNAK nucleoprotein | -0.0663221 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0633078 |
| EGFR | epidermal growth factor receptor | -0.0618107 |
| RPS6 | ribosomal protein S6 | -0.0605595 |
| PKM | pyruvate kinase, muscle | -0.0601043 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0536196 |
| VCL | vinculin | -0.0526692 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0503985 |
| RPLP1 | ribosomal protein, large, P1 | -0.0500555 |
| NBEA | neurobeachin | -0.0499421 |
| CCND1 | cyclin D1 | -0.0490247 |
| GLI2 | GLI family zinc finger 2 | -0.0489138 |
| LDHA | lactate dehydrogenase A | -0.0479491 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0477151 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0465343 |
| S100A10 | S100 calcium binding protein A10 | -0.0454737 |
| RPLP2 | ribosomal protein, large, P2 | -0.0451196 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0440992 |
| GLI3 | GLI family zinc finger 3 | -0.0440304 |
| RPL34 | ribosomal protein L34 | -0.0435051 |
| TMSB4X | thymosin beta 4, X-linked | -0.0434882 |
| S100A6 | S100 calcium binding protein A6 | -0.0425973 |
| RPL12 | ribosomal protein L12 | -0.0418018 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0414199 |
| ANXA1 | annexin A1 | -0.041293 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0396645 |
| EZR | ezrin | -0.0394231 |
| S100A4 | S100 calcium binding protein A4 | -0.0379199 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0377931 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0376642 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0375217 |
| RPS19 | ribosomal protein S19 | -0.0350435 |
| RPL7A | ribosomal protein L7a | -0.0347683 |
| RPS13 | ribosomal protein S13 | -0.0321666 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0320341 |
| RACK1 | receptor for activated C kinase 1 | -0.0319222 |
| RPL23 | ribosomal protein L23 | -0.0318959 |
| SLC38A2 | solute carrier family 38, member 2 | -0.031675 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0309942 |
| TCF12 | transcription factor 12 | -0.0309122 |
| RPS20 | ribosomal protein S20 | -0.0307742 |
| RPL26 | ribosomal protein L26 | -0.0305925 |
| RPL9 | ribosomal protein L9 | -0.0303857 |
| FLNB | filamin B, beta | -0.0303583 |
| RRBP1 | ribosome binding protein 1 | -0.0302721 |
| RPL19 | ribosomal protein L19 | -0.0298178 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.029769 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0293369 |
| TUBB4B | tubulin, beta 4B class IVb | -0.029226 |
| RPL7 | ribosomal protein L7 | -0.0286967 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0284903 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0284867 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0278461 |
| BMP10 | bone morphogenetic protein 10 | -0.0278443 |
| ATP9B | ATPase, class II, type 9B | -0.0277617 |
| RPS29 | ribosomal protein S29 | -0.0277186 |
| RPL13A | ribosomal protein L13a | -0.0276948 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0271622 |
| RPL27A | ribosomal protein L27a | -0.0270783 |
| RPS16 | ribosomal protein S16 | -0.0269737 |
| RPL11 | ribosomal protein L11 | -0.0267228 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0262116 |
| FUS | FUS RNA binding protein | -0.0258838 |
| YBX1 | Y box binding protein 1 | -0.0257162 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0256654 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0255587 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0255378 |
| MYO5C | myosin VC | -0.0253963 |
| RPLP0 | ribosomal protein, large, P0 | -0.0252719 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0252381 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0251003 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0250988 |
| MTAP | methylthioadenosine phosphorylase | -0.0250849 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0246029 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0244442 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0243734 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0240386 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0239121 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0238873 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0237923 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0237688 |
| CUX1 | cut-like homeobox 1 | -0.0236333 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0235629 |
| ATF4 | activating transcription factor 4 | -0.0234859 |
| TMSB10 | thymosin beta 10 | -0.0233569 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0230275 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.0228986 |
| BPTF | bromodomain PHD finger transcription factor | -0.0220718 |
| EXOC4 | exocyst complex component 4 | -0.0220448 |
| RPL35 | ribosomal protein L35 | -0.0219761 |
