| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0806046 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0666634 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0542082 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0464971 |
| FNIP1 | folliculin interacting protein 1 | 0.0440735 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0437348 |
| ATP13A3 | ATPase type 13A3 | 0.042011 |
| GOLGA4 | golgin A4 | 0.0400815 |
| ARRDC3 | arrestin domain containing 3 | 0.0400293 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0370843 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0370697 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0346725 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0333226 |
| SPAG9 | sperm associated antigen 9 | 0.0332334 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0330563 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0324726 |
| TPM3 | tropomyosin 3 | 0.0316307 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0295614 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0290227 |
| CENPF | centromere protein F, 350/400kDa | 0.0277855 |
| OGA | O-GlcNAcase | 0.0274059 |
| APP | amyloid beta (A4) precursor protein | 0.0271383 |
| STC1 | stanniocalcin 1 | 0.0267116 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0263821 |
| JMJD1C | jumonji domain containing 1C | 0.0257974 |
| SFTPA2 | surfactant protein A2 | 0.0256595 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0255831 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0253344 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.025263 |
| SET | SET nuclear proto-oncogene | 0.02526 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0252583 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.024642 |
| TPM4 | tropomyosin 4 | 0.024555 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0245188 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0241137 |
| IPO7 | importin 7 | 0.0240202 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0239602 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.022861 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0228559 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0227316 |
| CREBRF | CREB3 regulatory factor | 0.0226141 |
| CLTC | clathrin, heavy chain (Hc) | 0.0223514 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0223121 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0219951 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.021909 |
| ANLN | anillin, actin binding protein | 0.0215696 |
| NCKAP1 | NCK-associated protein 1 | 0.021563 |
| NUP153 | nucleoporin 153kDa | 0.0214163 |
| ZNF292 | zinc finger protein 292 | 0.0212821 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0212721 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0210117 |
| USP37 | ubiquitin specific peptidase 37 | 0.0209861 |
| CRY1 | cryptochrome circadian clock 1 | 0.0207978 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0204576 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0203603 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0202558 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0202325 |
| CUL3 | cullin 3 | 0.019968 |
| MATR3 | matrin 3 | 0.019709 |
| HBS1L | HBS1-like translational GTPase | 0.0196953 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0195623 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0193704 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0191685 |
| SNX9 | sorting nexin 9 | 0.019098 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0188603 |
| POTEF | POTE ankyrin domain family, member F | 0.0186417 |
| RPL4 | ribosomal protein L4 | 0.0185951 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0184631 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0183252 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0183025 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0182693 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0182535 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.018236 |
| ZNF654 | zinc finger protein 654 | 0.0181365 |
| RAB10 | RAB10, member RAS oncogene family | 0.018131 |
| KIF4A | kinesin family member 4A | 0.0180459 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0180165 |
| TTK | TTK protein kinase | 0.0179727 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0174774 |
| SUCO | SUN domain containing ossification factor | 0.0174642 |
| SERINC1 | serine incorporator 1 | 0.0173933 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0171197 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0169064 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0169034 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0168818 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0168407 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0167423 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0166633 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0166489 |
| RARS2 | arginyl-tRNA synthetase 2, mitochondrial | 0.016545 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0162528 |
| FOXO3 | forkhead box O3 | 0.016216 |
| DIAPH3 | diaphanous-related formin 3 | 0.0161953 |
| CDK19 | cyclin-dependent kinase 19 | 0.0160423 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0160222 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0159076 |
| CALR | calreticulin | 0.0159073 |
| UBQLN1 | ubiquilin 1 | 0.0158782 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0158398 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0157889 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.163302 |
| FN1 | fibronectin 1 | -0.162138 |
| VIM | vimentin | -0.128744 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.102539 |
| BICC1 | BicC family RNA binding protein 1 | -0.0807627 |
| TMSB10 | thymosin beta 10 | -0.0793163 |
| FRMD4A | FERM domain containing 4A | -0.0768168 |
| HLA-B | major histocompatibility complex, class I, B | -0.0761814 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0675822 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0630656 |
| RNF213 | ring finger protein 213 | -0.0600951 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0589085 |
| GLIS3 | GLIS family zinc finger 3 | -0.0588602 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0576523 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0561521 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0520067 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0512599 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0511809 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0504888 |
| COL6A3 | collagen, type VI, alpha 3 | -0.050447 |
| FTL | ferritin, light polypeptide | -0.0492681 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0457638 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0454358 |
| CADM1 | cell adhesion molecule 1 | -0.0449823 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0426379 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0423746 |
| TNS3 | tensin 3 | -0.0421941 |
| EGR1 | early growth response 1 | -0.0408934 |
| RPS6 | ribosomal protein S6 | -0.040416 |
| CTSD | cathepsin D | -0.0389966 |
| PLIN2 | perilipin 2 | -0.0387457 |
| C3 | complement component 3 | -0.0382671 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0378918 |
| DIAPH2 | diaphanous-related formin 2 | -0.0372392 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.037218 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0370877 |
| HLA-A | major histocompatibility complex, class I, A | -0.0369763 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0365855 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0360562 |
| MT2A | metallothionein 2A | -0.0359969 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0356027 |
| RPLP1 | ribosomal protein, large, P1 | -0.034496 |
| HLA-E | major histocompatibility complex, class I, E | -0.0344836 |
| NAV1 | neuron navigator 1 | -0.0339064 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0333438 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0327158 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0317784 |
| LDHA | lactate dehydrogenase A | -0.0310017 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0309621 |
| PMP22 | peripheral myelin protein 22 | -0.0308151 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0306853 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0306797 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0295069 |
| QKI | QKI, KH domain containing, RNA binding | -0.0294847 |
| NABP1 | nucleic acid binding protein 1 | -0.0292768 |
| RAI14 | retinoic acid induced 14 | -0.0290228 |
| RPL35A | ribosomal protein L35a | -0.028883 |
| RAD51B | RAD51 paralog B | -0.028366 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0279579 |
| LRRC7 | leucine rich repeat containing 7 | -0.0276378 |
| RPLP2 | ribosomal protein, large, P2 | -0.0275518 |
| RPS12 | ribosomal protein S12 | -0.0274034 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0270221 |
| FBXO32 | F-box protein 32 | -0.0270087 |
| RPS24 | ribosomal protein S24 | -0.0266571 |
| IER3 | immediate early response 3 | -0.0265462 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0263024 |
| SMAD3 | SMAD family member 3 | -0.0262448 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0262042 |
| SP100 | SP100 nuclear antigen | -0.0260555 |
| COL1A1 | collagen, type I, alpha 1 | -0.0259385 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0256492 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0256363 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0254175 |
| DST | dystonin | -0.0253571 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0252623 |
| SVIL | supervillin | -0.0250639 |
| RPS19 | ribosomal protein S19 | -0.0246989 |
| RIGI | RNA sensor RIG-I | -0.0246545 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0246177 |
| ASPH | aspartate beta-hydroxylase | -0.0245243 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0244414 |
| EGFR | epidermal growth factor receptor | -0.0240045 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0239838 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0237694 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0236517 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0236459 |
| NRP1 | neuropilin 1 | -0.0234268 |
| HMGA2 | high mobility group AT-hook 2 | -0.0231614 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0230992 |
| AUTS2 | autism susceptibility candidate 2 | -0.0230664 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0229342 |
| RPL36A | ribosomal protein L36a | -0.0227961 |
| ATXN1 | ataxin 1 | -0.0225703 |
| VMP1 | vacuole membrane protein 1 | -0.0224383 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0223728 |
| LOX | lysyl oxidase | -0.0221941 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0221312 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0220418 |
| PLSCR1 | phospholipid scramblase 1 | -0.0218778 |
