| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0906671 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0841514 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0733041 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0718 |
| RTN4 | reticulon 4 | 0.0705658 |
| ARRDC3 | arrestin domain containing 3 | 0.0653003 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0648639 |
| ANLN | anillin, actin binding protein | 0.064081 |
| B2M | beta-2-microglobulin | 0.0639535 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.059303 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.057271 |
| FAM13A | family with sequence similarity 13, member A | 0.0537266 |
| TPX2 | TPX2, microtubule-associated | 0.0521938 |
| HMGB2 | high mobility group box 2 | 0.0495561 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0461487 |
| ZNF292 | zinc finger protein 292 | 0.0451894 |
| MEF2A | myocyte enhancer factor 2A | 0.044819 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0447504 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0445894 |
| FOSL1 | FOS-like antigen 1 | 0.0445581 |
| ATP13A3 | ATPase type 13A3 | 0.0442333 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0442156 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0441944 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0424626 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0421189 |
| SGO2 | shugoshin 2 | 0.0419379 |
| RLIM | ring finger protein, LIM domain interacting | 0.0413844 |
| RNF24 | ring finger protein 24 | 0.0409404 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0397825 |
| SFXN1 | sideroflexin 1 | 0.0396712 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0394723 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0388701 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0387012 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0377803 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0372137 |
| ZNF207 | zinc finger protein 207 | 0.0365038 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0356062 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0354061 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0353065 |
| PTN | pleiotrophin | 0.0352613 |
| NOP58 | NOP58 ribonucleoprotein | 0.0346296 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0343329 |
| FRMD6 | FERM domain containing 6 | 0.033792 |
| KIF20B | kinesin family member 20B | 0.0330478 |
| ZNF451 | zinc finger protein 451 | 0.0328802 |
| CENPE | centromere protein E, 312kDa | 0.0326939 |
| TLN1 | talin 1 | 0.0326617 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0325111 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0323343 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0321756 |
| RBM39 | RNA binding motif protein 39 | 0.0316916 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.031524 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0313396 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0313381 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0310986 |
| H3-3B | H3.3 histone B | 0.0310772 |
| H2AZ2 | H2A.Z variant histone 2 | 0.0309953 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0306987 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0305866 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0301846 |
| CDC27 | cell division cycle 27 | 0.0300819 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0297704 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.029571 |
| USP15 | ubiquitin specific peptidase 15 | 0.029543 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.029539 |
| CADM1 | cell adhesion molecule 1 | 0.0294924 |
| SRP54 | signal recognition particle 54kDa | 0.029239 |
| FNIP1 | folliculin interacting protein 1 | 0.0291559 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0290672 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0285885 |
| RLF | rearranged L-myc fusion | 0.0285155 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0281864 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0279856 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0279525 |
| PCBP2 | poly(rC) binding protein 2 | 0.0279335 |
| KIF2C | kinesin family member 2C | 0.0278949 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0277633 |
| TXNRD1 | thioredoxin reductase 1 | 0.0277126 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0276534 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0275715 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0273213 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0273074 |
| TMEM39A | transmembrane protein 39A | 0.0272929 |
| TPM3 | tropomyosin 3 | 0.0269842 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0265062 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0263378 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0262892 |
| CD109 | CD109 molecule | 0.0262673 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0262658 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0261824 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0259802 |
| CCDC14 | coiled-coil domain containing 14 | 0.0257232 |
| CDCA2 | cell division cycle associated 2 | 0.0256968 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0255062 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0253903 |
| DCP2 | decapping mRNA 2 | 0.0253847 |
| MATR3 | matrin 3 | 0.025178 |
| RHEB | Ras homolog enriched in brain | 0.0249771 |
| MSN | moesin | 0.0248962 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0248443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.307333 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.167787 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.15469 |
| FN1 | fibronectin 1 | -0.13545 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0938131 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0924011 |
| COL1A1 | collagen, type I, alpha 1 | -0.0915695 |
| COL5A1 | collagen, type V, alpha 1 | -0.0860483 |
| VIM | vimentin | -0.0844232 |
| HLA-B | major histocompatibility complex, class I, B | -0.0820144 |
| TMSB10 | thymosin beta 10 | -0.0787586 |
| EGFR | epidermal growth factor receptor | -0.0782769 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0751541 |
| ENO1 | enolase 1, (alpha) | -0.0615554 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0606167 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0580678 |
| RRBP1 | ribosome binding protein 1 | -0.0572329 |
| GLIS3 | GLIS family zinc finger 3 | -0.0556201 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0519525 |
| NRXN3 | neurexin 3 | -0.050982 |
| HLA-C | major histocompatibility complex, class I, C | -0.0508633 |
| MT2A | metallothionein 2A | -0.0481909 |
| VCL | vinculin | -0.0445974 |
| HM13 | histocompatibility (minor) 13 | -0.0443143 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0442802 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0423759 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0422221 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0421099 |
| NAV1 | neuron navigator 1 | -0.0413842 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0411115 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0410407 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0404883 |
| RPL37A | ribosomal protein L37a | -0.0400229 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397731 |
| CAVIN1 | caveolae associated protein 1 | -0.0389736 |
| TRIM56 | tripartite motif containing 56 | -0.0386227 |
| HLA-A | major histocompatibility complex, class I, A | -0.0379106 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0378222 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0374271 |
| RPL34 | ribosomal protein L34 | -0.0359518 |
| PRSS23 | protease, serine, 23 | -0.0349141 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0347126 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0333349 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0332457 |
| S100A10 | S100 calcium binding protein A10 | -0.032968 |
| HIP1 | huntingtin interacting protein 1 | -0.0324555 |
| RPL37 | ribosomal protein L37 | -0.0324373 |
| COL6A1 | collagen, type VI, alpha 1 | -0.032221 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0317599 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0317198 |
| FAM20C | family with sequence similarity 20, member C | -0.0317133 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0314423 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0312549 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0304691 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0303136 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0302099 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0299948 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0294724 |
| CDK12 | cyclin-dependent kinase 12 | -0.0293696 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0290759 |
| ATG7 | autophagy related 7 | -0.0288079 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0284924 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0283499 |
| RPS23 | ribosomal protein S23 | -0.0282777 |
| CANX | calnexin | -0.0280237 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.027893 |
| PRKCA | protein kinase C, alpha | -0.0276623 |
| YEATS2 | YEATS domain containing 2 | -0.0274472 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0271976 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0271079 |
| FTL | ferritin, light polypeptide | -0.0269242 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0268532 |
| FLOT1 | flotillin 1 | -0.0268327 |
| FMNL2 | formin-like 2 | -0.0266255 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0264441 |
| STC2 | stanniocalcin 2 | -0.0264371 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0261568 |
| RPLP2 | ribosomal protein, large, P2 | -0.0259255 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0257477 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0256868 |
| OXR1 | oxidation resistance 1 | -0.025561 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0255339 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0249506 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0248682 |
| SNX14 | sorting nexin 14 | -0.0245985 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.024258 |
| RPS25 | ribosomal protein S25 | -0.0241924 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0241344 |
| RNF216 | ring finger protein 216 | -0.0240887 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0239942 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0239414 |
| SIL1 | SIL1 nucleotide exchange factor | -0.0238587 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0238334 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0236512 |
| APAF1 | apoptotic peptidase activating factor 1 | -0.0233558 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0232713 |
| CTSB | cathepsin B | -0.0232639 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0232029 |
| EGR1 | early growth response 1 | -0.0229221 |
| RPLP1 | ribosomal protein, large, P1 | -0.0227028 |
