| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0622867 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0611057 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.060237 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0551484 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0473231 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0453389 |
| VMP1 | vacuole membrane protein 1 | 0.0441134 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0413383 |
| GOLGA4 | golgin A4 | 0.0384538 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.037113 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0364524 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0352342 |
| SET | SET nuclear proto-oncogene | 0.035094 |
| CCNL1 | cyclin L1 | 0.034376 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0320915 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0299541 |
| JMJD1C | jumonji domain containing 1C | 0.0283592 |
| MATR3 | matrin 3 | 0.028352 |
| RBM39 | RNA binding motif protein 39 | 0.0277408 |
| TXNRD1 | thioredoxin reductase 1 | 0.0269975 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0269627 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.026961 |
| TPM3 | tropomyosin 3 | 0.0266114 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0264865 |
| CANX | calnexin | 0.0257176 |
| NCKAP1 | NCK-associated protein 1 | 0.0250521 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0246005 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.024449 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0241168 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0239555 |
| AHNAK | AHNAK nucleoprotein | 0.0238232 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0237024 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0236009 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.0234022 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0231564 |
| CRY1 | cryptochrome circadian clock 1 | 0.0230271 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0229263 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0223234 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0223123 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0218732 |
| ZNF654 | zinc finger protein 654 | 0.0215717 |
| GOLT1B | golgi transport 1B | 0.0215395 |
| CCND1 | cyclin D1 | 0.0211091 |
| DSPP | dentin sialophosphoprotein | 0.02105 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0209296 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0206528 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0205939 |
| SQSTM1 | sequestosome 1 | 0.0205576 |
| HMGB2 | high mobility group box 2 | 0.0204132 |
| RPL4 | ribosomal protein L4 | 0.0199211 |
| TES | testin LIM domain protein | 0.0198703 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0197405 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0193419 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0190643 |
| SUCO | SUN domain containing ossification factor | 0.0189573 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0189171 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0188035 |
| KIF5B | kinesin family member 5B | 0.0187764 |
| RBM27 | RNA binding motif protein 27 | 0.0187622 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0184312 |
| EPCAM | epithelial cell adhesion molecule | 0.0183058 |
| PERP | PERP, TP53 apoptosis effector | 0.0181821 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0181575 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0181305 |
| NEK7 | NIMA-related kinase 7 | 0.0179606 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0178865 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0178458 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0178039 |
| SPAG9 | sperm associated antigen 9 | 0.0177845 |
| FMR1 | fragile X mental retardation 1 | 0.0175824 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0174424 |
| B2M | beta-2-microglobulin | 0.0174212 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.01734 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.017296 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0171838 |
| MKRN1 | makorin ring finger protein 1 | 0.0171006 |
| RTN4 | reticulon 4 | 0.0170625 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0169745 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0168437 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0168024 |
| ACTN4 | actinin, alpha 4 | 0.0167617 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0165184 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0164524 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0162925 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0162829 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0162282 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0161579 |
| RNF114 | ring finger protein 114 | 0.0161476 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0159742 |
| MPZL3 | myelin protein zero-like 3 | 0.0159421 |
| ANLN | anillin, actin binding protein | 0.0158546 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0158305 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.015824 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0157793 |
| H3-3B | H3.3 histone B | 0.0157203 |
| XPO1 | exportin 1 | 0.015702 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0154662 |
| PAPOLA | poly(A) polymerase alpha | 0.0154223 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0154176 |
| DIDO1 | death inducer-obliterator 1 | 0.0153795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.0927513 |
| TMSB10 | thymosin beta 10 | -0.0765248 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0656595 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0652669 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0651261 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0532317 |
| PTMA | prothymosin, alpha | -0.0519087 |
| EHBP1 | EH domain binding protein 1 | -0.0514626 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0486612 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0467386 |
| RPLP1 | ribosomal protein, large, P1 | -0.0440923 |
| BCL2L1 | BCL2-like 1 | -0.0431159 |
| EGR1 | early growth response 1 | -0.0413343 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0407745 |
| ETV6 | ets variant 6 | -0.0393085 |
| RPS6 | ribosomal protein S6 | -0.0388327 |
| MSI2 | musashi RNA-binding protein 2 | -0.0384337 |
| ZNRF3 | zinc and ring finger 3 | -0.0380658 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0372969 |
| EXOC4 | exocyst complex component 4 | -0.0371476 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0358218 |
| RPL28 | ribosomal protein L28 | -0.0357226 |
| CADPS | Ca++-dependent secretion activator | -0.0356827 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0355711 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0345678 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0344917 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0337469 |
| RPLP2 | ribosomal protein, large, P2 | -0.0334414 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0326854 |
| TMEM123 | transmembrane protein 123 | -0.0325605 |
| NDRG1 | N-myc downstream regulated 1 | -0.0322867 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0321524 |
| RAD51B | RAD51 paralog B | -0.0319587 |
| LOC112694756 | uncharaterized LOC112694756 | -0.031075 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0307443 |
| RPL35A | ribosomal protein L35a | -0.0307402 |
| RNF213 | ring finger protein 213 | -0.0301793 |
| PKP4 | plakophilin 4 | -0.0300113 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0298468 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0297351 |
| TBC1D5 | TBC1 domain family, member 5 | -0.029359 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0289638 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0286664 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0283312 |
| SVIL | supervillin | -0.0282626 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0280204 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0278691 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0277097 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0274204 |
| RPL23 | ribosomal protein L23 | -0.0271338 |
| CUX1 | cut-like homeobox 1 | -0.027078 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.027016 |
| RPS21 | ribosomal protein S21 | -0.0267411 |
| PRELID2 | PRELI domain containing 2 | -0.0266572 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0263829 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0262843 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0262177 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.026026 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0257694 |
| PARD3B | par-3 family cell polarity regulator beta | -0.025433 |
| RPS19 | ribosomal protein S19 | -0.0253681 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0252975 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0248703 |
| NRP1 | neuropilin 1 | -0.0245767 |
| KRT18 | keratin 18, type I | -0.0245643 |
| WWOX | WW domain containing oxidoreductase | -0.0245574 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0244013 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0242486 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0240238 |
| RPS24 | ribosomal protein S24 | -0.023969 |
| RPL37A | ribosomal protein L37a | -0.0238661 |
| NAV2 | neuron navigator 2 | -0.0238431 |
| FRMD5 | FERM domain containing 5 | -0.0235008 |
| TGFA | transforming growth factor, alpha | -0.0233083 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0231743 |
| GNAS | GNAS complex locus | -0.0231559 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231211 |
| NHSL1 | NHS-like 1 | -0.0230053 |
| FAT1 | FAT atypical cadherin 1 | -0.0229761 |
| MED13L | mediator complex subunit 13-like | -0.0228828 |
| HMGA1 | high mobility group AT-hook 1 | -0.02278 |
| RPL35 | ribosomal protein L35 | -0.0227322 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0224282 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.022213 |
| RACK1 | receptor for activated C kinase 1 | -0.0221671 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0221202 |
| JUP | junction plakoglobin | -0.0220543 |
| VCL | vinculin | -0.0220265 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0219754 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0219186 |
| MYO1E | myosin IE | -0.0218722 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0217477 |
| RPS11 | ribosomal protein S11 | -0.0215586 |
| RPL12 | ribosomal protein L12 | -0.0215352 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0213398 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0207004 |
| RPL31 | ribosomal protein L31 | -0.0205406 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0204006 |
| PLSCR1 | phospholipid scramblase 1 | -0.0203722 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.020286 |
