| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.171582 |
| LMO7 | LIM domain 7 | 0.132658 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.100312 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0813954 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0743322 |
| GOLGA4 | golgin A4 | 0.0718434 |
| DSPP | dentin sialophosphoprotein | 0.0674843 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0651986 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0604894 |
| TXNRD1 | thioredoxin reductase 1 | 0.0577057 |
| EREG | epiregulin | 0.0570647 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0549745 |
| EZR | ezrin | 0.0510827 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0484401 |
| FERMT1 | fermitin family member 1 | 0.0478333 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0470998 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.046944 |
| ANXA1 | annexin A1 | 0.0450081 |
| ECT2 | epithelial cell transforming 2 | 0.044178 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0422635 |
| HDAC2 | histone deacetylase 2 | 0.0404353 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0403495 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0384549 |
| TES | testin LIM domain protein | 0.037286 |
| PLAUR | plasminogen activator, urokinase receptor | 0.036183 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.035245 |
| RAB10 | RAB10, member RAS oncogene family | 0.0344754 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0337445 |
| FNIP1 | folliculin interacting protein 1 | 0.0332223 |
| NCKAP1 | NCK-associated protein 1 | 0.0330917 |
| SBF2 | SET binding factor 2 | 0.0324656 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.032232 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0322215 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.032131 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0313091 |
| ANLN | anillin, actin binding protein | 0.03107 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0309723 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0306994 |
| RANBP9 | RAN binding protein 9 | 0.0306253 |
| USP24 | ubiquitin specific peptidase 24 | 0.029129 |
| HSPA4 | heat shock 70kDa protein 4 | 0.028991 |
| KITLG | KIT ligand | 0.0287253 |
| LAMC2 | laminin, gamma 2 | 0.0285293 |
| NCOR1 | nuclear receptor corepressor 1 | 0.028136 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0281125 |
| TNPO1 | transportin 1 | 0.0280598 |
| MED13L | mediator complex subunit 13-like | 0.0278311 |
| AHNAK | AHNAK nucleoprotein | 0.0275597 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0275127 |
| INSIG2 | insulin induced gene 2 | 0.027299 |
| SETD5 | SET domain containing 5 | 0.0269558 |
| USP34 | ubiquitin specific peptidase 34 | 0.0268634 |
| NBAS | neuroblastoma amplified sequence | 0.0267352 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0264497 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0264243 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0263296 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0261232 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0260797 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0259958 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.02571 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0256938 |
| KLC1 | kinesin light chain 1 | 0.0255375 |
| AREG | amphiregulin | 0.0255338 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0255188 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0254192 |
| TOP1 | topoisomerase (DNA) I | 0.0251945 |
| SETD2 | SET domain containing 2 | 0.0248834 |
| CD2AP | CD2-associated protein | 0.0248726 |
| MED13 | mediator complex subunit 13 | 0.0248416 |
| OGA | O-GlcNAcase | 0.0247468 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0246738 |
| ATL2 | atlastin GTPase 2 | 0.02464 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0245596 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0244956 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.024291 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0242686 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0242621 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0242535 |
| CANX | calnexin | 0.0241844 |
| NF1 | neurofibromin 1 | 0.0239777 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0238918 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0238272 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0233352 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0233174 |
| SNX9 | sorting nexin 9 | 0.023127 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0230313 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0230082 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0229294 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0228441 |
| RPL4 | ribosomal protein L4 | 0.0228297 |
| FLOT1 | flotillin 1 | 0.0227406 |
| CD47 | CD47 molecule | 0.0226767 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0226581 |
| WDR43 | WD repeat domain 43 | 0.0223066 |
| BBX | bobby sox homolog (Drosophila) | 0.0222652 |
| DUSP4 | dual specificity phosphatase 4 | 0.0221893 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0220987 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0220594 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0220017 |
| KIF5B | kinesin family member 5B | 0.0218145 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115147 |
| TMSB10 | thymosin beta 10 | -0.0971649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0859997 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0764817 |
| RPS19 | ribosomal protein S19 | -0.0736419 |
| RPL35A | ribosomal protein L35a | -0.0726642 |
| RPLP1 | ribosomal protein, large, P1 | -0.068236 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0681202 |
| ACTG1 | actin gamma 1 | -0.0673003 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0636051 |
| HMGA1 | high mobility group AT-hook 1 | -0.0592402 |
| RAD51B | RAD51 paralog B | -0.0562623 |
| RPS6 | ribosomal protein S6 | -0.0562062 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0506532 |
| RPL23 | ribosomal protein L23 | -0.050413 |
| FHIT | fragile histidine triad | -0.0502293 |
| GDF15 | growth differentiation factor 15 | -0.0492342 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0479208 |
| GPHN | gephyrin | -0.0467304 |
| RPL26 | ribosomal protein L26 | -0.0465815 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0442542 |
| EGFR | epidermal growth factor receptor | -0.0421842 |
| FHL2 | four and a half LIM domains 2 | -0.0376063 |
| S100A10 | S100 calcium binding protein A10 | -0.0361132 |
| PTMA | prothymosin, alpha | -0.0345255 |
| RPL19 | ribosomal protein L19 | -0.0340108 |
| RPS29 | ribosomal protein S29 | -0.0339688 |
| RPS25 | ribosomal protein S25 | -0.0336696 |
| TXNIP | thioredoxin interacting protein | -0.0334293 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0329059 |
| RPS8 | ribosomal protein S8 | -0.0328661 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0325462 |
| RPL9 | ribosomal protein L9 | -0.0324984 |
| RPL28 | ribosomal protein L28 | -0.0314179 |
| RPL34 | ribosomal protein L34 | -0.0303589 |
| KLK10 | kallikrein-related peptidase 10 | -0.0300898 |
| RPL37A | ribosomal protein L37a | -0.029532 |
| EGR1 | early growth response 1 | -0.0294329 |
| NDRG1 | N-myc downstream regulated 1 | -0.0280388 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0276635 |
| LAMB3 | laminin, beta 3 | -0.0269627 |
| RPS15 | ribosomal protein S15 | -0.0266372 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0262449 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260308 |
| RPS5 | ribosomal protein S5 | -0.0259866 |
| FTL | ferritin, light polypeptide | -0.0257111 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0253585 |
| RPL11 | ribosomal protein L11 | -0.025054 |
| HLA-B | major histocompatibility complex, class I, B | -0.0249558 |
| RPL31 | ribosomal protein L31 | -0.0248949 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.024743 |
| EHBP1 | EH domain binding protein 1 | -0.0244089 |
| PHF14 | PHD finger protein 14 | -0.0243722 |
| RPL12 | ribosomal protein L12 | -0.024222 |
| HLA-A | major histocompatibility complex, class I, A | -0.0239729 |
| RPL35 | ribosomal protein L35 | -0.0239411 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.023614 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0234602 |
| RPS2 | ribosomal protein S2 | -0.0234594 |
| MT2A | metallothionein 2A | -0.0231642 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0230835 |
| S100A6 | S100 calcium binding protein A6 | -0.0228121 |
| RPS21 | ribosomal protein S21 | -0.0225403 |
| RPL8 | ribosomal protein L8 | -0.022461 |
| MCL1 | myeloid cell leukemia 1 | -0.0224469 |
| RPL36 | ribosomal protein L36 | -0.0224098 |
| S100A9 | S100 calcium binding protein A9 | -0.0220706 |
| RPS20 | ribosomal protein S20 | -0.0215564 |
| LDHA | lactate dehydrogenase A | -0.0214715 |
| RPS17 | ribosomal protein S17 | -0.0208105 |
| RPS23 | ribosomal protein S23 | -0.0203352 |
| VCL | vinculin | -0.0200262 |
| RPL37 | ribosomal protein L37 | -0.0198823 |
| LMNA | lamin A/C | -0.0198796 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0195776 |
| RPL18 | ribosomal protein L18 | -0.0194493 |
| RPS4X | ribosomal protein S4, X-linked | -0.0193761 |
| PNN | pinin, desmosome associated protein | -0.0191934 |
| RPL36A | ribosomal protein L36a | -0.018882 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0186796 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0186525 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0184568 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0184552 |
| RPS13 | ribosomal protein S13 | -0.0180617 |
| RPL7A | ribosomal protein L7a | -0.0178911 |
| VIM | vimentin | -0.0178298 |
| VEGFA | vascular endothelial growth factor A | -0.0177948 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0175655 |
| RPL30 | ribosomal protein L30 | -0.0175034 |
| RPL38 | ribosomal protein L38 | -0.0173332 |
| RASAL2 | RAS protein activator like 2 | -0.0173169 |
| FOSL1 | FOS-like antigen 1 | -0.0169166 |
| RPL27A | ribosomal protein L27a | -0.0168597 |
| RPS14 | ribosomal protein S14 | -0.0166572 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.016575 |
| RPLP0 | ribosomal protein, large, P0 | -0.0165701 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0162798 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.015837 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0157927 |
| GNAS | GNAS complex locus | -0.0157168 |
