| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.198175 |
| B2M | beta-2-microglobulin | 0.137624 |
| FAM13A | family with sequence similarity 13, member A | 0.0923583 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0907486 |
| STC1 | stanniocalcin 1 | 0.0867102 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.078484 |
| ATP13A3 | ATPase type 13A3 | 0.0739077 |
| SPAG9 | sperm associated antigen 9 | 0.0723872 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0710103 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0685417 |
| DST | dystonin | 0.0670157 |
| SRP54 | signal recognition particle 54kDa | 0.0660784 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0655841 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0652973 |
| GOLGA4 | golgin A4 | 0.0622932 |
| TNPO1 | transportin 1 | 0.0602192 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0595918 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.058544 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0584746 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0564828 |
| MMP12 | matrix metallopeptidase 12 | 0.0550079 |
| HLA-B | major histocompatibility complex, class I, B | 0.0538544 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0531814 |
| NBAS | neuroblastoma amplified sequence | 0.0523338 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0516663 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0508277 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0501861 |
| ZNF292 | zinc finger protein 292 | 0.0482799 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0475969 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0469767 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0466744 |
| OGA | O-GlcNAcase | 0.0461811 |
| NUP58 | nucleoporin 58 | 0.0461527 |
| SETD5 | SET domain containing 5 | 0.0459543 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0459452 |
| FMNL2 | formin-like 2 | 0.0455587 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0451827 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0449114 |
| CANX | calnexin | 0.0441585 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0436489 |
| SUCO | SUN domain containing ossification factor | 0.0428273 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0424007 |
| RTN4 | reticulon 4 | 0.0412286 |
| FBN1 | fibrillin 1 | 0.0410042 |
| ENO1 | enolase 1, (alpha) | 0.040859 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0405974 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0402343 |
| TPM4 | tropomyosin 4 | 0.0402158 |
| FNIP1 | folliculin interacting protein 1 | 0.040143 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0399405 |
| CALR | calreticulin | 0.0385268 |
| VMP1 | vacuole membrane protein 1 | 0.0380395 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0379685 |
| HELZ | helicase with zinc finger | 0.0375594 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0374716 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0374548 |
| MORF4L2 | mortality factor 4 like 2 | 0.0374182 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0371461 |
| CLINT1 | clathrin interactor 1 | 0.0367062 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0366941 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0361697 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0358822 |
| ARF4 | ADP-ribosylation factor 4 | 0.0353926 |
| TMF1 | TATA element modulatory factor 1 | 0.0352231 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.034863 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0342402 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0340238 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0338332 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0337517 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.03341 |
| ADM | adrenomedullin | 0.0333972 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0333371 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0331182 |
| RASA2 | RAS p21 protein activator 2 | 0.0328537 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0328307 |
| KLHL24 | kelch-like family member 24 | 0.0327788 |
| CDC27 | cell division cycle 27 | 0.0327261 |
| CDK19 | cyclin-dependent kinase 19 | 0.032183 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0320416 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0318038 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0317323 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0316728 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0313955 |
| BBX | bobby sox homolog (Drosophila) | 0.0312894 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0311321 |
| TFG | TRK-fused gene | 0.0311104 |
| ARRDC3 | arrestin domain containing 3 | 0.0309495 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0309446 |
| PGK1 | phosphoglycerate kinase 1 | 0.0309043 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0308883 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0307864 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0306173 |
| PRELID2 | PRELI domain containing 2 | 0.0303633 |
| COPA | coatomer protein complex, subunit alpha | 0.0302075 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0300072 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0294423 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0293478 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0293237 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0289914 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0289775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147151 |
| COL6A3 | collagen, type VI, alpha 3 | -0.127971 |
| COL1A1 | collagen, type I, alpha 1 | -0.116586 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0750189 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0682305 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0662654 |
| FRMD4A | FERM domain containing 4A | -0.0614804 |
| SMAD3 | SMAD family member 3 | -0.0610356 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0602461 |
| EGFR | epidermal growth factor receptor | -0.0600362 |
| VCL | vinculin | -0.0585749 |
| NAV1 | neuron navigator 1 | -0.0574807 |
| TMSB10 | thymosin beta 10 | -0.0555001 |
| CALD1 | caldesmon 1 | -0.0532535 |
| ASPH | aspartate beta-hydroxylase | -0.05294 |
| COL5A3 | collagen, type V, alpha 3 | -0.0500014 |
| CD44 | CD44 molecule (Indian blood group) | -0.0482158 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0482057 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0449567 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0443026 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0437182 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0415053 |
| CCDC102B | coiled-coil domain containing 102B | -0.0378638 |
| FN1 | fibronectin 1 | -0.0360703 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0357089 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0345105 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0328711 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0327983 |
| ACTG1 | actin gamma 1 | -0.0314912 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0306577 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0291279 |
| PLPP3 | phospholipid phosphatase 3 | -0.0283128 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0282295 |
| COL1A2 | collagen, type I, alpha 2 | -0.0279625 |
| BPTF | bromodomain PHD finger transcription factor | -0.0270925 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0269993 |
| VIM | vimentin | -0.0266005 |
| FOXP1 | forkhead box P1 | -0.0263324 |
| OSMR | oncostatin M receptor | -0.0263006 |
| RPLP1 | ribosomal protein, large, P1 | -0.0260817 |
| ZNF644 | zinc finger protein 644 | -0.0258731 |
| PARVA | parvin, alpha | -0.0256935 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.02541 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0253296 |
| NDRG1 | N-myc downstream regulated 1 | -0.025134 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0249494 |
| CCND1 | cyclin D1 | -0.0247553 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0247247 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0246159 |
| SNAI2 | snail family zinc finger 2 | -0.0243505 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0242952 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0238783 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0238575 |
| DIAPH2 | diaphanous-related formin 2 | -0.0237492 |
| TPM1 | tropomyosin 1 (alpha) | -0.0237395 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0234387 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0232962 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0227645 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0225898 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0224425 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.0222713 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0222456 |
| H1-0 | H1.0 linker histone | -0.0220956 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0219918 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0219767 |
| EBF1 | early B-cell factor 1 | -0.0210732 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0210505 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0208449 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0208038 |
| EGR1 | early growth response 1 | -0.0207196 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0206854 |
| RPL27 | ribosomal protein L27 | -0.020585 |
| IPO9 | importin 9 | -0.0204938 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0204327 |
| NABP1 | nucleic acid binding protein 1 | -0.0201931 |
| PTMA | prothymosin, alpha | -0.0201418 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0199876 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0199861 |
| FLNA | filamin A, alpha | -0.0199409 |
| LOXL2 | lysyl oxidase-like 2 | -0.019915 |
| GPATCH8 | G patch domain containing 8 | -0.0196941 |
| INHBA | inhibin, beta A | -0.0196592 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0196212 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0195216 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.019448 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0193913 |
| KLF12 | Kruppel-like factor 12 | -0.0193868 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0193753 |
| RNF152 | ring finger protein 152 | -0.0190511 |
| AOPEP | aminopeptidase O (putative) | -0.0190504 |
| SEPTIN11 | septin 11 | -0.0188501 |
| MTAP | methylthioadenosine phosphorylase | -0.0187116 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0185596 |
| CAVIN1 | caveolae associated protein 1 | -0.0184881 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0183253 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0181191 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0180562 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0180538 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0179407 |
| CD82 | CD82 molecule | -0.0178474 |
