Phenylephrine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A member of the class of the class of phenylethanolamines that is 2-(methylamino)ethanol substituted by a 3-hydroxyphenyl group at position 1. (Chemical Entities of Biological Interest Ontology, CHEBI_8093)
External Link http://ctdbase.org/detail.go?type=chem&acc=D010656
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Genes

235 genes/proteins interacting with the chemical Phenylephrine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACTA1 actin, alpha 1, skeletal muscle
ADAM17 ADAM metallopeptidase domain 17
ADCY5 adenylate cyclase 5
ADM adrenomedullin
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADORA3 adenosine A3 receptor
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR2 angiotensin II receptor, type 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
APOE apolipoprotein E
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AVP arginine vasopressin
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BRD4 bromodomain containing 4
CA4 carbonic anhydrase IV
CABIN1 calcineurin binding protein 1
CALCA calcitonin-related polypeptide alpha
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNT1 cyclin T1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLU clusterin
CPT1B carnitine palmitoyltransferase 1B (muscle)
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYR61 cysteine-rich, angiogenic inducer, 61
DGKE diacylglycerol kinase, epsilon 64kDa
DGKZ diacylglycerol kinase, zeta
DIO2 deiodinase, iodothyronine, type II
DUSP6 dual specificity phosphatase 6
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FBN1 fibrillin 1
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO1 forkhead box O1
GATA4 GATA binding protein 4
GGT1 gamma-glutamyltransferase 1
GJA1 gap junction protein, alpha 1, 43kDa
GLA galactosidase, alpha
GLRX3 glutaredoxin 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GSK3B glycogen synthase kinase 3 beta
GYS2 glycogen synthase 2 (liver)
HDAC5 histone deacetylase 5
HEXIM1 hexamethylene bis-acetamide inducible 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
IER3 immediate early response 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP4 insulin-like growth factor binding protein 4
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1B interleukin 1, beta
ILK integrin-linked kinase
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNIP2 Kv channel interacting protein 2
KLF4 Kruppel-like factor 4 (gut)
LIMS1 LIM and senescent cell antigen-like domains 1
LPL lipoprotein lipase
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK9 mitogen-activated protein kinase 9
MEF2C myocyte enhancer factor 2C
MMP2 matrix metallopeptidase 2
MOV10L1 Mov10 RISC complex RNA helicase like 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBPC3 myosin binding protein C, cardiac
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL7 myosin, light chain 7, regulatory
MYL9 myosin, light chain 9, regulatory
MYLK3 myosin light chain kinase 3
MYOCD myocardin
MYOZ2 myozenin 2
NCF1 neutrophil cytosolic factor 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NODAL nodal growth differentiation factor
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPR1 natriuretic peptide receptor 1
NPY neuropeptide Y
NPY5R neuropeptide Y receptor Y5
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRG1 neuregulin 1
NTS neurotensin
OXT oxytocin/neurophysin I prepropeptide
PARP1 poly (ADP-ribose) polymerase 1
PARVA parvin, alpha
PCNA proliferating cell nuclear antigen
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDE5A phosphodiesterase 5A, cGMP-specific
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKLR pyruvate kinase, liver and RBC
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKG1 protein kinase, cGMP-dependent, type I
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PYGL phosphorylase, glycogen, liver
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RCAN1 regulator of calcineurin 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RGS2 regulator of G-protein signaling 2
RGS3 regulator of G-protein signaling 3
RGS4 regulator of G-protein signaling 4
RHOA ras homolog family member A
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRAD Ras-related associated with diabetes
S100A6 S100 calcium binding protein A6
S100B S100 calcium binding protein B
SGK1 serum/glucocorticoid regulated kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMAD2 SMAD family member 2
SPP1 secreted phosphoprotein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TFDP1 transcription factor Dp-1
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGM2 transglutaminase 2
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TIMP1 TIMP metallopeptidase inhibitor 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC2 tuberous sclerosis 2
TYR tyrosinase
UCN urocortin
VIP vasoactive intestinal peptide
WASL Wiskott-Aldrich syndrome-like
ZFPM2 zinc finger protein, FOG family member 2