| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.248521 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.230284 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.204317 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.193985 |
| FBN1 | fibrillin 1 | 0.179106 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.171214 |
| NAV1 | neuron navigator 1 | 0.150705 |
| THBS2 | thrombospondin 2 | 0.137352 |
| AHNAK | AHNAK nucleoprotein | 0.119647 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.106577 |
| LOXL2 | lysyl oxidase-like 2 | 0.106404 |
| LOX | lysyl oxidase | 0.0956451 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0850564 |
| COL3A1 | collagen, type III, alpha 1 | 0.0782338 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0771247 |
| COL5A2 | collagen, type V, alpha 2 | 0.0763575 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0750883 |
| VIM | vimentin | 0.0739452 |
| ANXA2 | annexin A2 | 0.0734952 |
| PLAT | plasminogen activator, tissue | 0.0695983 |
| FLNB | filamin B, beta | 0.0676944 |
| LDHA | lactate dehydrogenase A | 0.0647674 |
| FLNA | filamin A, alpha | 0.0628247 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0608597 |
| CD44 | CD44 molecule (Indian blood group) | 0.0578666 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0561109 |
| TPM4 | tropomyosin 4 | 0.0542583 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.052986 |
| SEPTIN9 | septin 9 | 0.0509302 |
| CTSB | cathepsin B | 0.0505957 |
| PLEC | plectin | 0.0502824 |
| CALR | calreticulin | 0.0498739 |
| MAP1B | microtubule-associated protein 1B | 0.0486032 |
| COL1A2 | collagen, type I, alpha 2 | 0.0480601 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0475015 |
| FRMD4A | FERM domain containing 4A | 0.0473932 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.047169 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0456177 |
| S100A6 | S100 calcium binding protein A6 | 0.0450334 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0439752 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0439133 |
| SQSTM1 | sequestosome 1 | 0.0437225 |
| TPM3 | tropomyosin 3 | 0.0435844 |
| TMSB4X | thymosin beta 4, X-linked | 0.0431027 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0426089 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0424002 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0421441 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.042106 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0414785 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0409582 |
| APP | amyloid beta (A4) precursor protein | 0.0409247 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0400144 |
| ATP13A3 | ATPase type 13A3 | 0.0392383 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0386104 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0385179 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0384484 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0383327 |
| PGK1 | phosphoglycerate kinase 1 | 0.0379381 |
| TPM1 | tropomyosin 1 (alpha) | 0.0356519 |
| SP3 | Sp3 transcription factor | 0.0356485 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0350365 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.034691 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0342544 |
| UBC | ubiquitin C | 0.0342462 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0341052 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0338666 |
| CDH13 | cadherin 13 | 0.0335097 |
| PRSS23 | protease, serine, 23 | 0.0334719 |
| RNF213 | ring finger protein 213 | 0.0328588 |
| RAI14 | retinoic acid induced 14 | 0.0327828 |
| AFDN | afadin, adherens junction formation factor | 0.0327451 |
| CANX | calnexin | 0.0327058 |
| AUTS2 | autism susceptibility candidate 2 | 0.0324248 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0322721 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0322131 |
| SUCNR1 | succinate receptor 1 | 0.0321123 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0317245 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0315855 |
| EHBP1 | EH domain binding protein 1 | 0.0315486 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0311829 |
| HLA-E | major histocompatibility complex, class I, E | 0.030937 |
| CD99 | CD99 molecule | 0.030588 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.030371 |
| CCND1 | cyclin D1 | 0.0301405 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0301022 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0300029 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0295392 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0293502 |
| TUBB | tubulin, beta class I | 0.0287663 |
| HDLBP | high density lipoprotein binding protein | 0.0285717 |
| KIFAP3 | kinesin-associated protein 3 | 0.0271281 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0268579 |
| MSN | moesin | 0.0267571 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0266692 |
| ADAR | adenosine deaminase, RNA-specific | 0.0264558 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0254863 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0252196 |
| CDK6 | cyclin-dependent kinase 6 | 0.0251541 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.025134 |
| MX2 | MX dynamin-like GTPase 2 | 0.0248425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.173419 |
| TMSB10 | thymosin beta 10 | -0.111828 |
| PTMA | prothymosin, alpha | -0.0596872 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0595367 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0493814 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0460874 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0401116 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0385495 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0334343 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0330714 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0324246 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0314467 |
| FTL | ferritin, light polypeptide | -0.0311433 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303028 |
| RPS19 | ribosomal protein S19 | -0.0291599 |
| RIGI | RNA sensor RIG-I | -0.0288334 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0276865 |
| RPS6 | ribosomal protein S6 | -0.027199 |
| RBM25 | RNA binding motif protein 25 | -0.0269905 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0265143 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0263285 |
| RBM39 | RNA binding motif protein 39 | -0.0260583 |
| JMJD1C | jumonji domain containing 1C | -0.0255185 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0250647 |
| SPAG9 | sperm associated antigen 9 | -0.0244944 |
| JUN | jun proto-oncogene | -0.0239463 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.023777 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0233217 |
| RPL36 | ribosomal protein L36 | -0.0232689 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0231587 |
| TLE4 | transducin-like enhancer of split 4 | -0.0231326 |
| RPL23 | ribosomal protein L23 | -0.0230445 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.022889 |
| RPL28 | ribosomal protein L28 | -0.0226361 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0226216 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0223947 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0223867 |
| MT1X | metallothionein 1X | -0.0221461 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221311 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0220994 |
| RPLP1 | ribosomal protein, large, P1 | -0.0220658 |
| FOSL1 | FOS-like antigen 1 | -0.0217525 |
| STC1 | stanniocalcin 1 | -0.0216234 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0214943 |
| RPL32 | ribosomal protein L32 | -0.0213519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0211103 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0210494 |
| CD109 | CD109 molecule | -0.020612 |
| GPHN | gephyrin | -0.0204853 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.02044 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0203621 |
| ZNF292 | zinc finger protein 292 | -0.0200749 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0200593 |
| ADM | adrenomedullin | -0.01992 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0193702 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0193052 |
| RPL31 | ribosomal protein L31 | -0.0191654 |
| ZNF462 | zinc finger protein 462 | -0.0190214 |
| RPL9 | ribosomal protein L9 | -0.0189721 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0187064 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.018501 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.018285 |
| RPL35A | ribosomal protein L35a | -0.0182308 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0182055 |
| RYBP | RING1 and YY1 binding protein | -0.0179979 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.017983 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0179006 |
| CALD1 | caldesmon 1 | -0.0178172 |
| COPA | coatomer protein complex, subunit alpha | -0.0177209 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.017634 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0175111 |
| HDAC9 | histone deacetylase 9 | -0.0173685 |
| SEC61G | Sec61 gamma subunit | -0.0172298 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0172189 |
| SEC24A | SEC24 family member A | -0.0170448 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0169723 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0168583 |
| MNT | MAX network transcriptional repressor | -0.0168198 |
| ANKRD30B | ankyrin repeat domain 30B | -0.0168063 |
| ERBIN | erbb2 interacting protein | -0.0167652 |
| RPL19 | ribosomal protein L19 | -0.016717 |
| PDE10A | phosphodiesterase 10A | -0.016635 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0165113 |
| BBX | bobby sox homolog (Drosophila) | -0.0164583 |
| MSI2 | musashi RNA-binding protein 2 | -0.0164571 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0163823 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0162993 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0162649 |
| INTS6 | integrator complex subunit 6 | -0.0162361 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0159272 |
| RREB1 | ras responsive element binding protein 1 | -0.0158909 |
| MTDH | metadherin | -0.0158808 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0157783 |
| HELZ | helicase with zinc finger | -0.0157133 |
| CADM1 | cell adhesion molecule 1 | -0.0156285 |
| NKTR | natural killer cell triggering receptor | -0.015603 |
| EGR1 | early growth response 1 | -0.0153718 |
| RPS8 | ribosomal protein S8 | -0.0153551 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0152793 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0151916 |
