| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.155683 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.124526 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0799249 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0753006 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0716795 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0684103 |
| PCBP2 | poly(rC) binding protein 2 | 0.0649885 |
| RPL3 | ribosomal protein L3 | 0.0620687 |
| TPM3 | tropomyosin 3 | 0.0496244 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0480038 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.047353 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0463988 |
| RPS3 | ribosomal protein S3 | 0.0441269 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0433601 |
| CPOX | coproporphyrinogen oxidase | 0.0405992 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0397003 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0390214 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0387091 |
| LDHB | lactate dehydrogenase B | 0.0382883 |
| CLDND1 | claudin domain containing 1 | 0.0370444 |
| TPI1 | triosephosphate isomerase 1 | 0.0365746 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0364752 |
| RPS12 | ribosomal protein S12 | 0.0364655 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0362841 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0350915 |
| SESN2 | sestrin 2 | 0.0341552 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0337271 |
| HDGF | hepatoma-derived growth factor | 0.0327992 |
| YBX1 | Y box binding protein 1 | 0.0322671 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0317324 |
| PLEC | plectin | 0.0316485 |
| SET | SET nuclear proto-oncogene | 0.0303355 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0301187 |
| POTEF | POTE ankyrin domain family, member F | 0.0299228 |
| HLA-A | major histocompatibility complex, class I, A | 0.0296481 |
| TXNRD1 | thioredoxin reductase 1 | 0.0285362 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0275136 |
| PNN | pinin, desmosome associated protein | 0.027314 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0268069 |
| RACK1 | receptor for activated C kinase 1 | 0.0259681 |
| HMGA1 | high mobility group AT-hook 1 | 0.0257553 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0254695 |
| RHOA | ras homolog family member A | 0.0252215 |
| MCL1 | myeloid cell leukemia 1 | 0.0250596 |
| ARRDC3 | arrestin domain containing 3 | 0.0250146 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0249062 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0248446 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0243207 |
| MED13L | mediator complex subunit 13-like | 0.0241917 |
| FLNA | filamin A, alpha | 0.0236573 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0230613 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0229536 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0229076 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0228933 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.022702 |
| RPS26 | ribosomal protein S26 | 0.0222113 |
| MSH6 | mutS homolog 6 | 0.0221832 |
| RPS4X | ribosomal protein S4, X-linked | 0.0219057 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0215714 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.0214048 |
| RPS2 | ribosomal protein S2 | 0.0210473 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0209741 |
| XPO1 | exportin 1 | 0.0205346 |
| NUP58 | nucleoporin 58 | 0.0203452 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0203127 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0201288 |
| TBK1 | TANK-binding kinase 1 | 0.0200955 |
| RPL27 | ribosomal protein L27 | 0.0200463 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0199588 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0192631 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0192316 |
| CEP250 | centrosomal protein 250kDa | 0.0191306 |
| SSRP1 | structure specific recognition protein 1 | 0.0189485 |
| PKM | pyruvate kinase, muscle | 0.0186639 |
| CALR | calreticulin | 0.0184078 |
| RPL7 | ribosomal protein L7 | 0.0183807 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0183465 |
| NONO | non-POU domain containing, octamer-binding | 0.018216 |
| ATXN2L | ataxin 2-like | 0.0181831 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0180387 |
| TCP1 | t-complex 1 | 0.0180135 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.017963 |
| CEP192 | centrosomal protein 192kDa | 0.0179112 |
| RPL29 | ribosomal protein L29 | 0.017895 |
| DSPP | dentin sialophosphoprotein | 0.0178604 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0178427 |
| PABPC1L | poly(A) binding protein, cytoplasmic 1-like | 0.017785 |
| PFN1 | profilin 1 | 0.0177175 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0177068 |
| FASN | fatty acid synthase | 0.017563 |
| MSN | moesin | 0.0175614 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0174362 |
| ATP11B | ATPase, class VI, type 11B | 0.016969 |
| ENO1 | enolase 1, (alpha) | 0.0169344 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0167289 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0167287 |
| GASK1B | golgi associated kinase 1B | 0.0166448 |
| FOSL1 | FOS-like antigen 1 | 0.0165766 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0165055 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0164957 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.254737 |
| NLGN1 | neuroligin 1 | -0.212664 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131987 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.127549 |
| PCDH7 | protocadherin 7 | -0.114551 |
| MMP12 | matrix metallopeptidase 12 | -0.107706 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0916272 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.074051 |
| VIM | vimentin | -0.07204 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0718576 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0687724 |
| AREG | amphiregulin | -0.0674622 |
| ZNF804A | zinc finger protein 804A | -0.0649995 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0637275 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0629219 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0607829 |
| DPYD | dihydropyrimidine dehydrogenase | -0.058444 |
| PTMA | prothymosin, alpha | -0.0574052 |
| TMSB10 | thymosin beta 10 | -0.0574001 |
| ADIPOR2 | adiponectin receptor 2 | -0.0542545 |
| EHBP1 | EH domain binding protein 1 | -0.0539579 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0516202 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0515796 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0514895 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0509279 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0505958 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0498546 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0487706 |
| FUS | FUS RNA binding protein | -0.0486037 |
| USP34 | ubiquitin specific peptidase 34 | -0.0483633 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0469264 |
| JMJD1C | jumonji domain containing 1C | -0.0463796 |
| DST | dystonin | -0.0448855 |
| HMGA2 | high mobility group AT-hook 2 | -0.0445641 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0440256 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0439792 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0437349 |
| MYPN | myopalladin | -0.0434424 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0426042 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.042316 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0421072 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413186 |
| ERBIN | erbb2 interacting protein | -0.0401435 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0391616 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0385959 |
| BCHE | butyrylcholinesterase | -0.0383129 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0380579 |
| GPHN | gephyrin | -0.0380329 |
| EDARADD | EDAR-associated death domain | -0.0376496 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0375164 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0374938 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0370479 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0363267 |
| MTAP | methylthioadenosine phosphorylase | -0.0360649 |
| AHNAK | AHNAK nucleoprotein | -0.0353875 |
| NABP1 | nucleic acid binding protein 1 | -0.0353542 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0349489 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0344986 |
| RBM39 | RNA binding motif protein 39 | -0.0344839 |
| BPTF | bromodomain PHD finger transcription factor | -0.0337325 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0334679 |
| RAB10 | RAB10, member RAS oncogene family | -0.0334439 |
| H1-0 | H1.0 linker histone | -0.0333256 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0333135 |
| SYT1 | synaptotagmin I | -0.0328058 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0326619 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0324767 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0324398 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0323379 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0322207 |
| RASAL2 | RAS protein activator like 2 | -0.0317949 |
| HDAC9 | histone deacetylase 9 | -0.0316583 |
| SETD5 | SET domain containing 5 | -0.0312894 |
| ZNF217 | zinc finger protein 217 | -0.0311157 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0305544 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0299631 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0297093 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0294133 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0293455 |
| RPS24 | ribosomal protein S24 | -0.0291586 |
| ATF6 | activating transcription factor 6 | -0.0286255 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0285637 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0283112 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0280485 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0280431 |
| CDK6 | cyclin-dependent kinase 6 | -0.0279998 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0279356 |
| CLDN1 | claudin 1 | -0.0277453 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0277312 |
| ZNF638 | zinc finger protein 638 | -0.0274346 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.027358 |
| ANKRD17 | ankyrin repeat domain 17 | -0.027338 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0273235 |
| RTN3 | reticulon 3 | -0.0271516 |
| NF1 | neurofibromin 1 | -0.0270866 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0270279 |
| SPAG9 | sperm associated antigen 9 | -0.0267457 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0267173 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0267016 |
| CEP112 | centrosomal protein 112kDa | -0.0265898 |
