| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.136912 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.120188 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0937073 |
| FAT1 | FAT atypical cadherin 1 | 0.0922349 |
| FLNA | filamin A, alpha | 0.0912661 |
| PLEC | plectin | 0.0882256 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0848554 |
| LOC112694756 | uncharaterized LOC112694756 | 0.082632 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.077765 |
| GPC6 | glypican 6 | 0.0744112 |
| FRMD4A | FERM domain containing 4A | 0.0742501 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0694536 |
| NDRG1 | N-myc downstream regulated 1 | 0.0672731 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0670278 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0669843 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0605803 |
| NAV2 | neuron navigator 2 | 0.0587726 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0545419 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0543307 |
| CADM1 | cell adhesion molecule 1 | 0.054007 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0531767 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0513155 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0472843 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0460733 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457985 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0443278 |
| COL4A2 | collagen, type IV, alpha 2 | 0.044257 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.044012 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0427669 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0424825 |
| DENND2B | DENN domain containing 2B | 0.041887 |
| ACTN1 | actinin, alpha 1 | 0.0416125 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0413352 |
| RNF213 | ring finger protein 213 | 0.0410901 |
| ATP13A3 | ATPase type 13A3 | 0.0410492 |
| ANXA2 | annexin A2 | 0.0394162 |
| FN1 | fibronectin 1 | 0.0381313 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0381049 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0379985 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0378921 |
| SURF4 | surfeit 4 | 0.0371145 |
| RPS4X | ribosomal protein S4, X-linked | 0.0370309 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0363827 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0363751 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0354836 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0352202 |
| CALR | calreticulin | 0.0349858 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0349644 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0343815 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0339458 |
| RPL3 | ribosomal protein L3 | 0.0326357 |
| HDLBP | high density lipoprotein binding protein | 0.031664 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0314993 |
| FLNC | filamin C, gamma | 0.0312271 |
| SMAD3 | SMAD family member 3 | 0.0312026 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0308406 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0303911 |
| ANXA5 | annexin A5 | 0.0301947 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0298034 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0295912 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0295006 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0293874 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0292682 |
| RUNX2 | runt-related transcription factor 2 | 0.0290185 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.028982 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0289303 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0284488 |
| FMNL2 | formin-like 2 | 0.0283899 |
| CTBP2 | C-terminal binding protein 2 | 0.0281 |
| TUBB | tubulin, beta class I | 0.0280319 |
| SEPTIN9 | septin 9 | 0.0280134 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0278122 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0276716 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0271127 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.026998 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0264196 |
| LRRC59 | leucine rich repeat containing 59 | 0.0261389 |
| SP3 | Sp3 transcription factor | 0.0256711 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | 0.0256257 |
| NEK6 | NIMA-related kinase 6 | 0.0254753 |
| CMIP | c-Maf inducing protein | 0.0253047 |
| PML | promyelocytic leukemia | 0.025048 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0248803 |
| SDCBP | syndecan binding protein (syntenin) | 0.0246275 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0242004 |
| ANKRD10 | ankyrin repeat domain 10 | 0.02415 |
| TLN1 | talin 1 | 0.0241499 |
| EGFR | epidermal growth factor receptor | 0.0240977 |
| CALU | calumenin | 0.0240791 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0237156 |
| LASP1 | LIM and SH3 protein 1 | 0.0235539 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0231466 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0231445 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0230543 |
| HPCAL1 | hippocalcin-like 1 | 0.0230408 |
| TNS1 | tensin 1 | 0.0230395 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.0229653 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0229306 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0228958 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227103 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.204264 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117534 |
| FTL | ferritin, light polypeptide | -0.0951243 |
| PTMA | prothymosin, alpha | -0.0776236 |
| RPS6 | ribosomal protein S6 | -0.0745828 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.055694 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0528629 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0509524 |
| MT2A | metallothionein 2A | -0.0499608 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0487038 |
| TXNRD1 | thioredoxin reductase 1 | -0.0483443 |
| B2M | beta-2-microglobulin | -0.0481408 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0468051 |
| RPS2 | ribosomal protein S2 | -0.0423208 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0401389 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0400018 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.039446 |
| UBC | ubiquitin C | -0.0380622 |
| MAP1B | microtubule-associated protein 1B | -0.0370522 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.035683 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0338433 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.033804 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0325854 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0325306 |
| HLA-B | major histocompatibility complex, class I, B | -0.0320051 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0301865 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0297053 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0296648 |
| RPL28 | ribosomal protein L28 | -0.0291725 |
| UBXN4 | UBX domain protein 4 | -0.0290798 |
| RPS24 | ribosomal protein S24 | -0.0288487 |
| CDCP1 | CUB domain containing protein 1 | -0.028755 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0286105 |
| CA12 | carbonic anhydrase XII | -0.0279797 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0278277 |
| RPL19 | ribosomal protein L19 | -0.0278059 |
| MTDH | metadherin | -0.0272175 |
| TMSB10 | thymosin beta 10 | -0.027128 |
| IFI44L | interferon-induced protein 44-like | -0.027017 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0262587 |
| NRP2 | neuropilin 2 | -0.0258845 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0258546 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0257594 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0255432 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0253391 |
| SETD5 | SET domain containing 5 | -0.0253295 |
| RPS8 | ribosomal protein S8 | -0.025281 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0251721 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0249539 |
| S100A10 | S100 calcium binding protein A10 | -0.0248459 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0248122 |
| RPS27A | ribosomal protein S27a | -0.0244892 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0241223 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0239738 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0236991 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.023681 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0232965 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0232258 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0225102 |
| GOLGA4 | golgin A4 | -0.0224936 |
| EFNA5 | ephrin-A5 | -0.0222967 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0221694 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0221042 |
| H3-3B | H3.3 histone B | -0.02187 |
| TUSC3 | tumor suppressor candidate 3 | -0.0218028 |
| GOLM2 | golgi membrane protein 2 | -0.021682 |
| RPLP2 | ribosomal protein, large, P2 | -0.0215798 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0215152 |
| FUS | FUS RNA binding protein | -0.02141 |
| TUBA1B | tubulin, alpha 1b | -0.0213131 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0209891 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0209804 |
| CBX3 | chromobox homolog 3 | -0.0209073 |
| EFCAB14 | EF-hand calcium binding domain 14 | -0.0207899 |
| SELENOF | selenoprotein F | -0.020697 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0205426 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0205026 |
| SQSTM1 | sequestosome 1 | -0.0203911 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0202603 |
| RPS5 | ribosomal protein S5 | -0.0201864 |
| MYADM | myeloid-associated differentiation marker | -0.0200239 |
| RRBP1 | ribosome binding protein 1 | -0.0199831 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0197569 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0197294 |
| NF1 | neurofibromin 1 | -0.0194872 |
| RO60 | Ro60, Y RNA binding protein | -0.019452 |
| CP | ceruloplasmin (ferroxidase) | -0.0193777 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0193175 |
| ANLN | anillin, actin binding protein | -0.0192859 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0191108 |
| TRIM56 | tripartite motif containing 56 | -0.0189958 |
| RPS13 | ribosomal protein S13 | -0.0189743 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0186895 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0186299 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0185627 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0185338 |
| R3HDM1 | R3H domain containing 1 | -0.018426 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0184105 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0183996 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0183843 |
