| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.201086 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.103461 |
| PLEC | plectin | 0.0962572 |
| NAV2 | neuron navigator 2 | 0.0953868 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0932146 |
| ANXA2 | annexin A2 | 0.0900773 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0785018 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0753371 |
| FLNB | filamin B, beta | 0.065596 |
| FLNA | filamin A, alpha | 0.0598675 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0594441 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0562311 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0555563 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0541986 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0532514 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.04871 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0480881 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0471576 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0463357 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0459971 |
| HELZ | helicase with zinc finger | 0.0444339 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0436736 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0436112 |
| FMNL2 | formin-like 2 | 0.0427972 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0425508 |
| ACTN4 | actinin, alpha 4 | 0.0417158 |
| MCL1 | myeloid cell leukemia 1 | 0.040684 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0404581 |
| NDRG1 | N-myc downstream regulated 1 | 0.0386677 |
| AHNAK | AHNAK nucleoprotein | 0.0379372 |
| USP3 | ubiquitin specific peptidase 3 | 0.0364265 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0362201 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0343585 |
| FAM107B | family with sequence similarity 107, member B | 0.0340164 |
| WDR43 | WD repeat domain 43 | 0.0333708 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0332199 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0325022 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0320332 |
| CORO1C | coronin, actin binding protein, 1C | 0.03134 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0311069 |
| PGK1 | phosphoglycerate kinase 1 | 0.0310926 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0310041 |
| CTBP2 | C-terminal binding protein 2 | 0.0308953 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0300271 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0298215 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0293593 |
| KRT18 | keratin 18, type I | 0.0291318 |
| SPAG9 | sperm associated antigen 9 | 0.0290036 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0289441 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0286695 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0285119 |
| MYOF | myoferlin | 0.0283946 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.028394 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0283515 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0283038 |
| CLTC | clathrin, heavy chain (Hc) | 0.0281069 |
| DENND1A | DENN/MADD domain containing 1A | 0.0274838 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0273373 |
| TUBB | tubulin, beta class I | 0.0272475 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0272402 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.027063 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0265495 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0257706 |
| WDR45B | WD repeat domain 45B | 0.0256401 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.025472 |
| NUP58 | nucleoporin 58 | 0.0250632 |
| RASA2 | RAS p21 protein activator 2 | 0.0249323 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0243219 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.024214 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0241807 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0239227 |
| SEPTIN9 | septin 9 | 0.0239021 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0235297 |
| MATR3 | matrin 3 | 0.023434 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0233517 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0232072 |
| TOP1 | topoisomerase (DNA) I | 0.0231706 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0231403 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0231361 |
| MINK1 | misshapen-like kinase 1 | 0.0226965 |
| DENND4A | DENN/MADD domain containing 4A | 0.0225686 |
| AFDN | afadin, adherens junction formation factor | 0.0223792 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0223526 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0219749 |
| IPO7 | importin 7 | 0.0219461 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0219145 |
| CMIP | c-Maf inducing protein | 0.0218381 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0217459 |
| TBC1D22A | TBC1 domain family, member 22A | 0.020993 |
| NBAS | neuroblastoma amplified sequence | 0.0209687 |
| NF1 | neurofibromin 1 | 0.0209608 |
| NEK6 | NIMA-related kinase 6 | 0.0208432 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0207706 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0204297 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0203424 |
| KRT7 | keratin 7, type II | 0.0202933 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0200595 |
| HDLBP | high density lipoprotein binding protein | 0.0199864 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0199357 |
| CA8 | carbonic anhydrase VIII | 0.0199258 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.176118 |
| TMSB10 | thymosin beta 10 | -0.152025 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128228 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.100865 |
| VIM | vimentin | -0.0941678 |
| MT2A | metallothionein 2A | -0.0841457 |
| PTMA | prothymosin, alpha | -0.0829898 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0774788 |
| RPS6 | ribosomal protein S6 | -0.0720745 |
| RPS19 | ribosomal protein S19 | -0.058115 |
| FTL | ferritin, light polypeptide | -0.0467208 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0456782 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0454589 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0454317 |
| MT1X | metallothionein 1X | -0.045234 |
| EHBP1 | EH domain binding protein 1 | -0.0451697 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0449065 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0433787 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0363748 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0360807 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0352929 |
| RPL23 | ribosomal protein L23 | -0.0350352 |
| MYADM | myeloid-associated differentiation marker | -0.0343611 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0332995 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0322698 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0319797 |
| AUTS2 | autism susceptibility candidate 2 | -0.0318081 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0317413 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0316849 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0313715 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0313284 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.031093 |
| VCL | vinculin | -0.0307433 |
| PFN1 | profilin 1 | -0.0301674 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.029816 |
| BPTF | bromodomain PHD finger transcription factor | -0.029554 |
| CA12 | carbonic anhydrase XII | -0.0292007 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0289337 |
| PARD3 | par-3 family cell polarity regulator | -0.0277252 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0277139 |
| SP100 | SP100 nuclear antigen | -0.0276079 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0275912 |
| RPL35A | ribosomal protein L35a | -0.027381 |
| STC1 | stanniocalcin 1 | -0.0271229 |
| RPS8 | ribosomal protein S8 | -0.0270856 |
| SEPTIN7 | septin 7 | -0.0266864 |
| KRT81 | keratin 81, type II | -0.025876 |
| BICC1 | BicC family RNA binding protein 1 | -0.0257192 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0253451 |
| RPL31 | ribosomal protein L31 | -0.0253032 |
| RPL12 | ribosomal protein L12 | -0.0248713 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0248644 |
| NRP1 | neuropilin 1 | -0.0244999 |
| MYO1E | myosin IE | -0.0244268 |
| EGFR | epidermal growth factor receptor | -0.024311 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0241367 |
| RDX | radixin | -0.0240023 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0234147 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0231705 |
| EFNA5 | ephrin-A5 | -0.0230921 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0225874 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0224951 |
| ASTN2 | astrotactin 2 | -0.022424 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0223977 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0223614 |
| OSMR | oncostatin M receptor | -0.0223592 |
| EGR1 | early growth response 1 | -0.0219421 |
| PTGR1 | prostaglandin reductase 1 | -0.0211357 |
| TPM4 | tropomyosin 4 | -0.0209682 |
| RPL32 | ribosomal protein L32 | -0.0205892 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0203889 |
| DUSP16 | dual specificity phosphatase 16 | -0.0202647 |
| PKM | pyruvate kinase, muscle | -0.02018 |
| RPS13 | ribosomal protein S13 | -0.0201591 |
| B2M | beta-2-microglobulin | -0.0201084 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0199604 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0197963 |
| RPLP2 | ribosomal protein, large, P2 | -0.0197935 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0196995 |
| RPS11 | ribosomal protein S11 | -0.0195748 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.01956 |
| LMO7 | LIM domain 7 | -0.019245 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0191923 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0191228 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0190158 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0190115 |
| RPS14 | ribosomal protein S14 | -0.0187926 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0186923 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0182862 |
| HM13 | histocompatibility (minor) 13 | -0.0181578 |
| S100A6 | S100 calcium binding protein A6 | -0.0181392 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0180973 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0180898 |
| CP | ceruloplasmin (ferroxidase) | -0.0180636 |
| GPC6 | glypican 6 | -0.0179656 |
| S100A11 | S100 calcium binding protein A11 | -0.0179535 |
| RPS25 | ribosomal protein S25 | -0.0178834 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0178234 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0178043 |
| FBXO11 | F-box protein 11 | -0.0174801 |
