| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACACA | acetyl-CoA carboxylase alpha | 0.1994 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.117472 |
| CEP250 | centrosomal protein 250kDa | 0.105929 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0954772 |
| CLTC | clathrin, heavy chain (Hc) | 0.0939299 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0899346 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0768832 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0759052 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0689025 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0681009 |
| PTK2 | protein tyrosine kinase 2 | 0.0665865 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0640389 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0629528 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0610394 |
| ASPH | aspartate beta-hydroxylase | 0.060658 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0593577 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0589906 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0578808 |
| SEPTIN9 | septin 9 | 0.0569529 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0567483 |
| KRT7 | keratin 7, type II | 0.0559596 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0558897 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0498161 |
| LASP1 | LIM and SH3 protein 1 | 0.0492888 |
| NCOA6 | nuclear receptor coactivator 6 | 0.049201 |
| FASN | fatty acid synthase | 0.0490716 |
| MLPH | melanophilin | 0.0485985 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0481327 |
| PLEC | plectin | 0.0473703 |
| MYO5B | myosin VB | 0.0466476 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.043983 |
| DENND1A | DENN/MADD domain containing 1A | 0.0433274 |
| VMP1 | vacuole membrane protein 1 | 0.0424022 |
| CCND1 | cyclin D1 | 0.0414981 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0410892 |
| GSE1 | Gse1 coiled-coil protein | 0.0410127 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0409493 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0405376 |
| MACROD1 | MACRO domain containing 1 | 0.0398531 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0395767 |
| AHNAK | AHNAK nucleoprotein | 0.0393155 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0380629 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.0380101 |
| CDK12 | cyclin-dependent kinase 12 | 0.0368514 |
| LRRC59 | leucine rich repeat containing 59 | 0.036784 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0360437 |
| ORMDL3 | ORMDL sphingolipid biosynthesis regulator 3 | 0.035537 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0354892 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.035421 |
| ACTG1 | actin gamma 1 | 0.0351688 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0351434 |
| POTEF | POTE ankyrin domain family, member F | 0.0343324 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0342604 |
| PGK1 | phosphoglycerate kinase 1 | 0.0336354 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0331666 |
| TTC6 | tetratricopeptide repeat domain 6 | 0.0324509 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0322271 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0319735 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.031937 |
| ATXN1 | ataxin 1 | 0.0318973 |
| SMYD3 | SET and MYND domain containing 3 | 0.0314027 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0313529 |
| KIF16B | kinesin family member 16B | 0.0306396 |
| PRKCA | protein kinase C, alpha | 0.0302219 |
| MYO6 | myosin VI | 0.029688 |
| VCP | valosin containing protein | 0.0293969 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0293723 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.02925 |
| HDLBP | high density lipoprotein binding protein | 0.0290871 |
| ENO1 | enolase 1, (alpha) | 0.0289984 |
| COBL | cordon-bleu WH2 repeat protein | 0.028984 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.028268 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0281427 |
| FADS2 | fatty acid desaturase 2 | 0.0280429 |
| KRT18 | keratin 18, type I | 0.027715 |
| MCL1 | myeloid cell leukemia 1 | 0.0273407 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0271258 |
| NCOA2 | nuclear receptor coactivator 2 | 0.027056 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0270074 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.026655 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0266241 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0265989 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264555 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0263506 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0256655 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0251482 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | 0.0251393 |
| TUBB | tubulin, beta class I | 0.0248932 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0247886 |
| PARD3 | par-3 family cell polarity regulator | 0.0247689 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0247526 |
| KRT86 | keratin 86, type II | 0.0247004 |
| TENM4 | teneurin transmembrane protein 4 | 0.0245611 |
| KIF1A | kinesin family member 1A | 0.0239617 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0239466 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0238231 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0238046 |
| EGFR | epidermal growth factor receptor | 0.0234201 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0234173 |
| ANXA2 | annexin A2 | 0.0233928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.256087 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.164585 |
| PTMA | prothymosin, alpha | -0.109632 |
| RPL19 | ribosomal protein L19 | -0.100383 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.081552 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0704041 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0700538 |
| TMSB10 | thymosin beta 10 | -0.0604668 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0582953 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0581532 |
| MT2A | metallothionein 2A | -0.0576233 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0555449 |
| S100A8 | S100 calcium binding protein A8 | -0.0539326 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0515284 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0495259 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0484469 |
| RPL35A | ribosomal protein L35a | -0.0463711 |
| RPS12 | ribosomal protein S12 | -0.0419693 |
| S100A9 | S100 calcium binding protein A9 | -0.0416483 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0414836 |
| RPS19 | ribosomal protein S19 | -0.0409795 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0408182 |
| RPLP1 | ribosomal protein, large, P1 | -0.0407747 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0406572 |
| CCNI | cyclin I | -0.0402226 |
| RPL12 | ribosomal protein L12 | -0.039929 |
| RPL26 | ribosomal protein L26 | -0.0399109 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0398711 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0394542 |
| CCNL1 | cyclin L1 | -0.0387479 |
| TXNRD1 | thioredoxin reductase 1 | -0.0379408 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0376941 |
| B2M | beta-2-microglobulin | -0.0363083 |
| RPS6 | ribosomal protein S6 | -0.0357204 |
| TMEM165 | transmembrane protein 165 | -0.0351007 |
| RPS24 | ribosomal protein S24 | -0.0345285 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0332841 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0330562 |
| KIAA1217 | KIAA1217 | -0.0327757 |
| PFDN4 | prefoldin subunit 4 | -0.0326277 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0322987 |
| RBM25 | RNA binding motif protein 25 | -0.0322506 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0322111 |
| RBM39 | RNA binding motif protein 39 | -0.0317137 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0314218 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0308291 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0298493 |
| RPS27A | ribosomal protein S27a | -0.0296533 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0293449 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0292532 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.028967 |
| NTN4 | netrin 4 | -0.0288462 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0283464 |
| ZNF292 | zinc finger protein 292 | -0.0283389 |
| S100A14 | S100 calcium binding protein A14 | -0.028203 |
| EHF | ets homologous factor | -0.0281728 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0280793 |
| KLF6 | Kruppel-like factor 6 | -0.027775 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0272107 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0271816 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.027152 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0271375 |
| RPL37A | ribosomal protein L37a | -0.0271349 |
| S100A7 | S100 calcium binding protein A7 | -0.0271279 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0270121 |
| OSMR | oncostatin M receptor | -0.0266874 |
| HMGB1 | high mobility group box 1 | -0.0266438 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0264505 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.026412 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0263678 |
| USP53 | ubiquitin specific peptidase 53 | -0.0261948 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0261337 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0260224 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0254197 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0252809 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0251019 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0248933 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0248534 |
| YBX3 | Y box binding protein 3 | -0.0244432 |
| RIOK3 | RIO kinase 3 | -0.0240813 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0239223 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0237502 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0237461 |
| RPL9 | ribosomal protein L9 | -0.0237296 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0235374 |
| HLA-B | major histocompatibility complex, class I, B | -0.0230431 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0229948 |
| KITLG | KIT ligand | -0.022961 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0228741 |
| MATR3 | matrin 3 | -0.0225698 |
| SERF2 | small EDRK-rich factor 2 | -0.0224992 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0222466 |
| USP3 | ubiquitin specific peptidase 3 | -0.0221947 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0221904 |
| ENAH | enabled homolog (Drosophila) | -0.0221493 |
| RNF24 | ring finger protein 24 | -0.0217393 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0217034 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.021685 |
| FBXO32 | F-box protein 32 | -0.0215636 |
| RPS27 | ribosomal protein S27 | -0.0214878 |
