| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.173409 |
| LAMB3 | laminin, beta 3 | 0.16061 |
| NDRG1 | N-myc downstream regulated 1 | 0.135455 |
| ANXA2 | annexin A2 | 0.131199 |
| HLA-C | major histocompatibility complex, class I, C | 0.128539 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.126271 |
| LOC112694756 | uncharaterized LOC112694756 | 0.111094 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0981996 |
| TMSB4X | thymosin beta 4, X-linked | 0.0976158 |
| SMAD3 | SMAD family member 3 | 0.0972976 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0961359 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0958666 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0929765 |
| FAM13A | family with sequence similarity 13, member A | 0.0916384 |
| ACTG1 | actin gamma 1 | 0.0849394 |
| FLNB | filamin B, beta | 0.0805338 |
| SPAG9 | sperm associated antigen 9 | 0.0805117 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0790511 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0777917 |
| PGK1 | phosphoglycerate kinase 1 | 0.0770462 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0717084 |
| EZR | ezrin | 0.0711978 |
| LAMC2 | laminin, gamma 2 | 0.0702971 |
| CCNY | cyclin Y | 0.0698127 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0681402 |
| PLEC | plectin | 0.0675381 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0653861 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0630755 |
| DTNA | dystrobrevin, alpha | 0.0630356 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.062708 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0618563 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0618431 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0616848 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0610656 |
| HSPA8 | heat shock 70kDa protein 8 | 0.060113 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0600829 |
| AHNAK | AHNAK nucleoprotein | 0.0594461 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0584511 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0572898 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0558197 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0548669 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0534397 |
| ASPH | aspartate beta-hydroxylase | 0.0527365 |
| APP | amyloid beta (A4) precursor protein | 0.0507392 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0505902 |
| FLNA | filamin A, alpha | 0.0498896 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0480803 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0475167 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0449644 |
| HPCAL1 | hippocalcin-like 1 | 0.04472 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0444097 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0443131 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0441059 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0440571 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.044034 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0432247 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0427368 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0421487 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0418592 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0417671 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0414454 |
| MEF2A | myocyte enhancer factor 2A | 0.0407136 |
| OGA | O-GlcNAcase | 0.0400899 |
| MCL1 | myeloid cell leukemia 1 | 0.039106 |
| WDR45B | WD repeat domain 45B | 0.0390894 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0389473 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.038665 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0383135 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0381954 |
| OPTN | optineurin | 0.0378707 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0377986 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.037532 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0372427 |
| HDLBP | high density lipoprotein binding protein | 0.0370347 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0367507 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0366549 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0361145 |
| YTHDC1 | YTH domain containing 1 | 0.0358014 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0355017 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0352935 |
| DSPP | dentin sialophosphoprotein | 0.0349996 |
| LAMA4 | laminin, alpha 4 | 0.0348048 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0347306 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0346421 |
| LASP1 | LIM and SH3 protein 1 | 0.0345115 |
| ENO1 | enolase 1, (alpha) | 0.0343081 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0342017 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0339837 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0339439 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0335763 |
| YBX1 | Y box binding protein 1 | 0.0331483 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0330532 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0330168 |
| FNBP1L | formin binding protein 1-like | 0.032533 |
| CDC73 | cell division cycle 73 | 0.0315934 |
| CALR | calreticulin | 0.0312501 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0310055 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0309524 |
| ARRDC3 | arrestin domain containing 3 | 0.0308869 |
| ACTN4 | actinin, alpha 4 | 0.0308572 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.299074 |
| MT2A | metallothionein 2A | -0.163366 |
| FTL | ferritin, light polypeptide | -0.081663 |
| HLA-B | major histocompatibility complex, class I, B | -0.0747317 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.067172 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0514184 |
| B2M | beta-2-microglobulin | -0.0505675 |
| TMSB10 | thymosin beta 10 | -0.050312 |
| S100A10 | S100 calcium binding protein A10 | -0.0487233 |
| RPS29 | ribosomal protein S29 | -0.0443205 |
| PTMA | prothymosin, alpha | -0.0442495 |
| RPS23 | ribosomal protein S23 | -0.0439222 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0431385 |
| LCN2 | lipocalin 2 | -0.0419159 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0414327 |
| EGR1 | early growth response 1 | -0.0395863 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.038175 |
| RPS25 | ribosomal protein S25 | -0.0358898 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0358571 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0346116 |
| RPS6 | ribosomal protein S6 | -0.0327922 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0318468 |
| RPS8 | ribosomal protein S8 | -0.0316864 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0309656 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0309068 |
| RPL28 | ribosomal protein L28 | -0.0306297 |
| BPTF | bromodomain PHD finger transcription factor | -0.030246 |
| NABP1 | nucleic acid binding protein 1 | -0.0300842 |
| HMGA1 | high mobility group AT-hook 1 | -0.0299458 |
| RPS24 | ribosomal protein S24 | -0.0298074 |
| TXNIP | thioredoxin interacting protein | -0.0296628 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0294441 |
| RPL19 | ribosomal protein L19 | -0.0279893 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0279664 |
| RPL31 | ribosomal protein L31 | -0.027884 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0278105 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0275305 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0274174 |
| RPL36A | ribosomal protein L36a | -0.0272433 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0269413 |
| RPS11 | ribosomal protein S11 | -0.0267042 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.026396 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255827 |
| MX2 | MX dynamin-like GTPase 2 | -0.0255408 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0250946 |
| CCNI | cyclin I | -0.023831 |
| RPL8 | ribosomal protein L8 | -0.0237325 |
| PLAT | plasminogen activator, tissue | -0.0235954 |
| RPS19 | ribosomal protein S19 | -0.0235938 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.023022 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0229273 |
| GPHN | gephyrin | -0.022865 |
| RPLP2 | ribosomal protein, large, P2 | -0.0227035 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0221858 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.022047 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0220213 |
| RPL9 | ribosomal protein L9 | -0.0218808 |
| RPS16 | ribosomal protein S16 | -0.0218062 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.021698 |
| RPS14 | ribosomal protein S14 | -0.0216751 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0215015 |
| PMP22 | peripheral myelin protein 22 | -0.0214174 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0212479 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0210864 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0206995 |
| NUMB | numb homolog (Drosophila) | -0.0202679 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0200008 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0198983 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0193489 |
| CDCP1 | CUB domain containing protein 1 | -0.0187857 |
| HDAC9 | histone deacetylase 9 | -0.0186399 |
| RPS10 | ribosomal protein S10 | -0.0185824 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.018567 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0185044 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0184572 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0183737 |
| S100A11 | S100 calcium binding protein A11 | -0.0183533 |
| UBC | ubiquitin C | -0.0182684 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0182624 |
| MUC1 | mucin 1, cell surface associated | -0.0182218 |
| BCL2L1 | BCL2-like 1 | -0.0181306 |
| AREG | amphiregulin | -0.0181084 |
| RPL23 | ribosomal protein L23 | -0.017855 |
| PKM | pyruvate kinase, muscle | -0.0178311 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0176446 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0175524 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0174685 |
| MT1E | metallothionein 1E | -0.0172955 |
| RPS15 | ribosomal protein S15 | -0.0172734 |
| INTS6 | integrator complex subunit 6 | -0.0172198 |
| NRP1 | neuropilin 1 | -0.017083 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0170757 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0170701 |
| KRT19 | keratin 19, type I | -0.0169554 |
| FUS | FUS RNA binding protein | -0.0167575 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0164962 |
| TMC5 | transmembrane channel-like 5 | -0.0164282 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0163492 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0163277 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0162551 |
