| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.18928 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.109489 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.101637 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0823568 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0563213 |
| NDRG1 | N-myc downstream regulated 1 | 0.050012 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0463719 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0456597 |
| PLEC | plectin | 0.0454452 |
| HDLBP | high density lipoprotein binding protein | 0.043539 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0410789 |
| WDR45B | WD repeat domain 45B | 0.0375503 |
| CTBP2 | C-terminal binding protein 2 | 0.0359085 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340981 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0309514 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0308998 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0308002 |
| KRT18 | keratin 18, type I | 0.030423 |
| CALR | calreticulin | 0.0281238 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0279621 |
| TUBB | tubulin, beta class I | 0.0277275 |
| RPL3 | ribosomal protein L3 | 0.0274774 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0274769 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0250207 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0241966 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0231782 |
| FLNA | filamin A, alpha | 0.0231503 |
| HYOU1 | hypoxia up-regulated 1 | 0.0228431 |
| PER1 | period circadian clock 1 | 0.022747 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0226494 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0224205 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0220304 |
| GANAB | glucosidase, alpha; neutral AB | 0.0218818 |
| RNF213 | ring finger protein 213 | 0.0212424 |
| RNF43 | ring finger protein 43 | 0.0209082 |
| ARF1 | ADP-ribosylation factor 1 | 0.0208278 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.020368 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0196025 |
| ATXN2L | ataxin 2-like | 0.0190783 |
| SEC24C | SEC24 family member C | 0.0188018 |
| ARCN1 | archain 1 | 0.0187365 |
| KAZN | kazrin, periplakin interacting protein | 0.0185548 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0184714 |
| FOXO3 | forkhead box O3 | 0.018385 |
| GOLGA2 | golgin A2 | 0.0183418 |
| TPM3 | tropomyosin 3 | 0.0174216 |
| FAM117B | family with sequence similarity 117, member B | 0.0168612 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0168488 |
| MLEC | malectin | 0.0168013 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0166292 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0165981 |
| HOXB3 | homeobox B3 | 0.016489 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0162654 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0162034 |
| CCND1 | cyclin D1 | 0.0161593 |
| RPS4X | ribosomal protein S4, X-linked | 0.0159722 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0159147 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0157965 |
| SURF4 | surfeit 4 | 0.0157752 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0156781 |
| ASS1 | argininosuccinate synthase 1 | 0.0156156 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0153914 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.015139 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0150586 |
| SRP54 | signal recognition particle 54kDa | 0.0149304 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0147335 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0147235 |
| CADPS | Ca++-dependent secretion activator | 0.0146141 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 0.0145184 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.014492 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0144612 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0142996 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0142818 |
| JUP | junction plakoglobin | 0.0142498 |
| HOXB9 | homeobox B9 | 0.0142446 |
| ZNF24 | zinc finger protein 24 | 0.0140773 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0140689 |
| RPS9 | ribosomal protein S9 | 0.0139571 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0137229 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.0136998 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | 0.0135731 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0135404 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0134509 |
| KHNYN | KH and NYN domain containing | 0.0133868 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0133595 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0133238 |
| VEGFA | vascular endothelial growth factor A | 0.0133065 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0132323 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.013208 |
| HPCAL1 | hippocalcin-like 1 | 0.0131394 |
| SRPRA | SRP receptor subunit alpha | 0.0131243 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.0130781 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0130382 |
| ERH | enhancer of rudimentary homolog (Drosophila) | 0.0130005 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0129888 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0127899 |
| XPOT | exportin, tRNA | 0.0127236 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.012704 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0127016 |
| DAZAP1 | DAZ associated protein 1 | 0.0126547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.502319 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.102709 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0824554 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0773155 |
| RPS2 | ribosomal protein S2 | -0.0769801 |
| RPS6 | ribosomal protein S6 | -0.0766219 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0742956 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0635987 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0607558 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0601464 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0588161 |
| ASPH | aspartate beta-hydroxylase | -0.0572869 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0560199 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0538941 |
| VMP1 | vacuole membrane protein 1 | -0.0537347 |
| ZNF638 | zinc finger protein 638 | -0.051326 |
| USP34 | ubiquitin specific peptidase 34 | -0.0508993 |
| RPS8 | ribosomal protein S8 | -0.0473866 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.047128 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0451951 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0441561 |
| MT2A | metallothionein 2A | -0.0440045 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0438069 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0428264 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0428054 |
| PRELID2 | PRELI domain containing 2 | -0.0427764 |
| OGA | O-GlcNAcase | -0.0426315 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0424302 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0422794 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0419924 |
| MYO9A | myosin IXA | -0.0415806 |
| SETD5 | SET domain containing 5 | -0.0414543 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0413191 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0404866 |
| RPL37A | ribosomal protein L37a | -0.0401811 |
| RBM39 | RNA binding motif protein 39 | -0.0398301 |
| GOLGB1 | golgin B1 | -0.0397212 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0392282 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0389969 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0389392 |
| GPHN | gephyrin | -0.0375063 |
| S100A10 | S100 calcium binding protein A10 | -0.0374243 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0373782 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0372159 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0362349 |
| RPLP2 | ribosomal protein, large, P2 | -0.0360644 |
| NEBL | nebulette | -0.0356658 |
| CLTC | clathrin, heavy chain (Hc) | -0.035554 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.035415 |
| NKTR | natural killer cell triggering receptor | -0.0351786 |
| RNF24 | ring finger protein 24 | -0.0347497 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0347105 |
| SMYD3 | SET and MYND domain containing 3 | -0.0345561 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0344546 |
| WWC2 | WW and C2 domain containing 2 | -0.0337817 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0331889 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0330082 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0323447 |
| KIF5B | kinesin family member 5B | -0.0322831 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0320391 |
| EZR | ezrin | -0.0319498 |
| TXNRD1 | thioredoxin reductase 1 | -0.0317831 |
| DSPP | dentin sialophosphoprotein | -0.0315344 |
| RPS27A | ribosomal protein S27a | -0.0312355 |
| RPL26 | ribosomal protein L26 | -0.0312309 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0311506 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0310998 |
| RPL5 | ribosomal protein L5 | -0.0310167 |
| RPS12 | ribosomal protein S12 | -0.0309263 |
| SNX14 | sorting nexin 14 | -0.0309215 |
| NF1 | neurofibromin 1 | -0.0307771 |
| VCL | vinculin | -0.0306013 |
| ZNF654 | zinc finger protein 654 | -0.0304534 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0303359 |
| RPL7 | ribosomal protein L7 | -0.0302328 |
| GOLGA4 | golgin A4 | -0.0300563 |
| RPL7A | ribosomal protein L7a | -0.0299521 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0298937 |
| RPL11 | ribosomal protein L11 | -0.02989 |
| TJP1 | tight junction protein 1 | -0.0297401 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0293008 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0290317 |
| RPS3 | ribosomal protein S3 | -0.0287642 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0286788 |
| CDK19 | cyclin-dependent kinase 19 | -0.0286706 |
| PAPOLA | poly(A) polymerase alpha | -0.0286647 |
| RSPH3 | radial spoke 3 homolog (Chlamydomonas) | -0.0283288 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0282382 |
| RPL32 | ribosomal protein L32 | -0.0280809 |
| SON | SON DNA binding protein | -0.0280117 |
| RPL31 | ribosomal protein L31 | -0.0277306 |
| JMJD1C | jumonji domain containing 1C | -0.027704 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0276789 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0275343 |
| RAB10 | RAB10, member RAS oncogene family | -0.0275279 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0272745 |
| MCL1 | myeloid cell leukemia 1 | -0.0272388 |
| BBX | bobby sox homolog (Drosophila) | -0.0270309 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.027025 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0270014 |
