| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.181049 |
| TXNRD1 | thioredoxin reductase 1 | 0.145575 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0954424 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0729056 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0711994 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0685623 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0581283 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0521017 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0517746 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0513193 |
| PLEC | plectin | 0.051177 |
| FRY | furry homolog (Drosophila) | 0.0499719 |
| FBXO32 | F-box protein 32 | 0.0497154 |
| ANXA2 | annexin A2 | 0.0489604 |
| LDHA | lactate dehydrogenase A | 0.0470578 |
| HYOU1 | hypoxia up-regulated 1 | 0.0462794 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0450262 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0442009 |
| HDLBP | high density lipoprotein binding protein | 0.0436258 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0426075 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0417983 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0411214 |
| SQSTM1 | sequestosome 1 | 0.0410296 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0404556 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0402899 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0391451 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0381869 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0381025 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0378941 |
| AHNAK | AHNAK nucleoprotein | 0.0365134 |
| DST | dystonin | 0.0354146 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0345417 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0322624 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0322036 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0309304 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0298196 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0288875 |
| ZNF292 | zinc finger protein 292 | 0.0287389 |
| ABHD2 | abhydrolase domain containing 2 | 0.0287045 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0284681 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0284439 |
| ATF3 | activating transcription factor 3 | 0.0283485 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0280383 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0279301 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0276519 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0270695 |
| ARF1 | ADP-ribosylation factor 1 | 0.0270574 |
| YME1L1 | YME1-like 1 ATPase | 0.0270215 |
| LAMB3 | laminin, beta 3 | 0.0267839 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0263979 |
| ARF4 | ADP-ribosylation factor 4 | 0.0263255 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0254651 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0252052 |
| CLINT1 | clathrin interactor 1 | 0.025154 |
| FNIP1 | folliculin interacting protein 1 | 0.0250321 |
| RPL3 | ribosomal protein L3 | 0.0250026 |
| GOLGA2 | golgin A2 | 0.0249423 |
| GOLGB1 | golgin B1 | 0.0247879 |
| ATXN1 | ataxin 1 | 0.0246408 |
| CALR | calreticulin | 0.0246379 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0245644 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0245496 |
| CCNY | cyclin Y | 0.0243187 |
| HOXB3 | homeobox B3 | 0.0242001 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.024129 |
| ARFGEF3 | ARFGEF family member 3 | 0.0239888 |
| NBAS | neuroblastoma amplified sequence | 0.0239782 |
| RAB11A | RAB11A, member RAS oncogene family | 0.0238546 |
| NCKAP1 | NCK-associated protein 1 | 0.0235337 |
| SUCO | SUN domain containing ossification factor | 0.0234096 |
| PTEN | phosphatase and tensin homolog | 0.0232162 |
| FAM13A | family with sequence similarity 13, member A | 0.0230574 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0227419 |
| RNF43 | ring finger protein 43 | 0.0226956 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0225906 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0222083 |
| CLTC | clathrin, heavy chain (Hc) | 0.0221647 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0221094 |
| EXPH5 | exophilin 5 | 0.0220315 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0217603 |
| GOLGA4 | golgin A4 | 0.0217301 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.0216435 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0216198 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0216003 |
| PDZD8 | PDZ domain containing 8 | 0.0211221 |
| CALU | calumenin | 0.0210826 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.020971 |
| TNS1 | tensin 1 | 0.0209327 |
| PRKCE | protein kinase C, epsilon | 0.0205486 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0203189 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0202951 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.020282 |
| GOLGA3 | golgin A3 | 0.0201937 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0201875 |
| NBEAL1 | neurobeachin-like 1 | 0.020137 |
| CDK8 | cyclin-dependent kinase 8 | 0.0200385 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0200325 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0199717 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0198437 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0195739 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.160127 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.110084 |
| RPS6 | ribosomal protein S6 | -0.104151 |
| TMSB10 | thymosin beta 10 | -0.101698 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.101255 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0988048 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0941227 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0923444 |
| RPL23 | ribosomal protein L23 | -0.0842177 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0838871 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0826495 |
| TJP1 | tight junction protein 1 | -0.0821138 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0808759 |
| FTL | ferritin, light polypeptide | -0.0803096 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0798047 |
| RPS19 | ribosomal protein S19 | -0.0769795 |
| LAMA4 | laminin, alpha 4 | -0.0738976 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0736236 |
| SMAD3 | SMAD family member 3 | -0.072786 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0669724 |
| RPS8 | ribosomal protein S8 | -0.0661349 |
| VCL | vinculin | -0.065014 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0626284 |
| EGR1 | early growth response 1 | -0.0607817 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.060597 |
| RPLP1 | ribosomal protein, large, P1 | -0.059996 |
| BCL2L1 | BCL2-like 1 | -0.059808 |
| RPL35A | ribosomal protein L35a | -0.0585236 |
| S100A10 | S100 calcium binding protein A10 | -0.0571829 |
| RPLP2 | ribosomal protein, large, P2 | -0.0562152 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0498883 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0497677 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0482323 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0474353 |
| AREG | amphiregulin | -0.0455665 |
| NTN4 | netrin 4 | -0.0452602 |
| B2M | beta-2-microglobulin | -0.0444855 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0437406 |
| WWC1 | WW and C2 domain containing 1 | -0.0436262 |
| MYO1E | myosin IE | -0.0435568 |
| WASF2 | WAS protein family, member 2 | -0.042404 |
| LMO7 | LIM domain 7 | -0.0420017 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0393458 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0387777 |
| RPL9 | ribosomal protein L9 | -0.038696 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0385934 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0381099 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0367701 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0366105 |
| STK24 | serine/threonine kinase 24 | -0.036187 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0361843 |
| FLNB | filamin B, beta | -0.0360685 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.035697 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0356586 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.035433 |
| RPL34 | ribosomal protein L34 | -0.035333 |
| RNF24 | ring finger protein 24 | -0.0348887 |
| KLF10 | Kruppel-like factor 10 | -0.0346292 |
| RPS23 | ribosomal protein S23 | -0.0337653 |
| TRIB1 | tribbles pseudokinase 1 | -0.0337543 |
| FOXO1 | forkhead box O1 | -0.0337317 |
| SGMS2 | sphingomyelin synthase 2 | -0.0336444 |
| HMGB1 | high mobility group box 1 | -0.0328605 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0327319 |
| RPL28 | ribosomal protein L28 | -0.0324155 |
| RPS24 | ribosomal protein S24 | -0.03235 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0323446 |
| RPS27A | ribosomal protein S27a | -0.0321673 |
| KLK10 | kallikrein-related peptidase 10 | -0.0321475 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0319495 |
| ASTN2 | astrotactin 2 | -0.0318534 |
| RPS14 | ribosomal protein S14 | -0.0318321 |
| RPL5 | ribosomal protein L5 | -0.0314871 |
| RPS12 | ribosomal protein S12 | -0.0313458 |
| ETV6 | ets variant 6 | -0.0312167 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0309351 |
| LIMA1 | LIM domain and actin binding 1 | -0.0306698 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0303228 |
| RPL18 | ribosomal protein L18 | -0.0303002 |
| JMJD1C | jumonji domain containing 1C | -0.0302404 |
| RPS21 | ribosomal protein S21 | -0.0298327 |
| RPL37A | ribosomal protein L37a | -0.029423 |
| SERF2 | small EDRK-rich factor 2 | -0.0293309 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0291626 |
| RPS25 | ribosomal protein S25 | -0.028998 |
| RPL19 | ribosomal protein L19 | -0.028956 |
| LATS2 | large tumor suppressor kinase 2 | -0.028805 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0284903 |
| RPS13 | ribosomal protein S13 | -0.0283802 |
| RPL31 | ribosomal protein L31 | -0.0278599 |
| RPL36A | ribosomal protein L36a | -0.0277533 |
| MYO1D | myosin ID | -0.0276811 |
| RPS11 | ribosomal protein S11 | -0.027625 |
| CBX3 | chromobox homolog 3 | -0.0275471 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0275125 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0271421 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0267591 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0266109 |
| VMP1 | vacuole membrane protein 1 | -0.02614 |
| RPL12 | ribosomal protein L12 | -0.0260961 |
