| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.151713 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0734737 |
| TXNRD1 | thioredoxin reductase 1 | 0.071826 |
| ATP13A3 | ATPase type 13A3 | 0.058442 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0531641 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0501541 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0493609 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0488163 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0464421 |
| FLNB | filamin B, beta | 0.0442971 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0439616 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.039409 |
| ARF4 | ADP-ribosylation factor 4 | 0.0378052 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0364965 |
| FLNA | filamin A, alpha | 0.0338778 |
| B2M | beta-2-microglobulin | 0.0324025 |
| TPM3 | tropomyosin 3 | 0.0323779 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0323093 |
| NUP58 | nucleoporin 58 | 0.031559 |
| POTEF | POTE ankyrin domain family, member F | 0.0298289 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0286251 |
| BCL2L1 | BCL2-like 1 | 0.0286099 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0274368 |
| FOSL1 | FOS-like antigen 1 | 0.0274176 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0272171 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0266015 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0239249 |
| RAB6A | RAB6A, member RAS oncogene family | 0.023139 |
| KRT7 | keratin 7, type II | 0.0229408 |
| UBC | ubiquitin C | 0.0228892 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0226366 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0223617 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0222877 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0219839 |
| TPD52 | tumor protein D52 | 0.0218798 |
| TMEM41B | transmembrane protein 41B | 0.0217465 |
| AFAP1 | actin filament associated protein 1 | 0.0217175 |
| CALR | calreticulin | 0.021536 |
| RLIM | ring finger protein, LIM domain interacting | 0.0215248 |
| MCL1 | myeloid cell leukemia 1 | 0.021473 |
| SURF4 | surfeit 4 | 0.0212694 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0208505 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0207183 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0205997 |
| MSN | moesin | 0.0203737 |
| DENND4C | DENN/MADD domain containing 4C | 0.0199724 |
| TUBB | tubulin, beta class I | 0.0197885 |
| RTN4 | reticulon 4 | 0.0197784 |
| NUP153 | nucleoporin 153kDa | 0.0196696 |
| PCBP2 | poly(rC) binding protein 2 | 0.0194564 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0193823 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0190496 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0190406 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0186261 |
| GOLGA4 | golgin A4 | 0.0186052 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0185541 |
| CALU | calumenin | 0.0184517 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0180362 |
| COG5 | component of oligomeric golgi complex 5 | 0.0178951 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0178352 |
| OSMR | oncostatin M receptor | 0.0178174 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0177224 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0176756 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0176696 |
| ANXA5 | annexin A5 | 0.0174626 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0172638 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0171163 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0171145 |
| TGFB2 | transforming growth factor, beta 2 | 0.0170887 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.0168655 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.016764 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | 0.016733 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0166471 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0165335 |
| PLK2 | polo-like kinase 2 | 0.0163838 |
| TBK1 | TANK-binding kinase 1 | 0.0162431 |
| NEK7 | NIMA-related kinase 7 | 0.0162256 |
| TRAM1 | translocation associated membrane protein 1 | 0.0162066 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0161502 |
| TUBA1B | tubulin, alpha 1b | 0.0160946 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0160553 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0160483 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0160033 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0159882 |
| GPR107 | G protein-coupled receptor 107 | 0.0159442 |
| NSUN2 | NOP2/Sun RNA methyltransferase family, member 2 | 0.0159263 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0159159 |
| TMEM39A | transmembrane protein 39A | 0.0158549 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0158266 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0158168 |
| ATP11B | ATPase, class VI, type 11B | 0.0158018 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0157595 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0157095 |
| RPL3 | ribosomal protein L3 | 0.0156265 |
| SCFD2 | sec1 family domain containing 2 | 0.0155603 |
| GOLT1B | golgi transport 1B | 0.0155535 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0154204 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0154076 |
| HLA-A | major histocompatibility complex, class I, A | 0.0153278 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0151776 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.254886 |
| FN1 | fibronectin 1 | -0.153171 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.132792 |
| MT2A | metallothionein 2A | -0.116144 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.114615 |
| EXT1 | exostosin glycosyltransferase 1 | -0.113183 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.107875 |
| INTS6 | integrator complex subunit 6 | -0.0904774 |
| FTL | ferritin, light polypeptide | -0.0734942 |
| TLE4 | transducin-like enhancer of split 4 | -0.0647098 |
| AHNAK | AHNAK nucleoprotein | -0.0573841 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0556591 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0551685 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0516999 |
| TMSB10 | thymosin beta 10 | -0.0500388 |
| RPL35A | ribosomal protein L35a | -0.0487487 |
| PRELID2 | PRELI domain containing 2 | -0.0471642 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0459256 |
| ZNF804A | zinc finger protein 804A | -0.0445592 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.044257 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0431088 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0427557 |
| HLA-B | major histocompatibility complex, class I, B | -0.0421787 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0418593 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0413155 |
| ASPH | aspartate beta-hydroxylase | -0.0407892 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0402484 |
| DTNA | dystrobrevin, alpha | -0.0401116 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.039976 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0396283 |
| VCL | vinculin | -0.0392494 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.039088 |
| GLIS3 | GLIS family zinc finger 3 | -0.0388632 |
| CAVIN1 | caveolae associated protein 1 | -0.0385126 |
| DST | dystonin | -0.0381974 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0377125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0369644 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0365903 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0356467 |
| DIAPH3 | diaphanous-related formin 3 | -0.0353874 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0353777 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0351423 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0344837 |
| PTMA | prothymosin, alpha | -0.0344378 |
| RAD51B | RAD51 paralog B | -0.0330807 |
| NABP1 | nucleic acid binding protein 1 | -0.0328906 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0328866 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0325823 |
| TENM3 | teneurin transmembrane protein 3 | -0.0325343 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0325061 |
| E2F3 | E2F transcription factor 3 | -0.0322964 |
| ACTG1 | actin gamma 1 | -0.0320179 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0313703 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0312436 |
| RPS6 | ribosomal protein S6 | -0.0312341 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0302909 |
| SMYD3 | SET and MYND domain containing 3 | -0.0298099 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0293994 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0293445 |
| RIGI | RNA sensor RIG-I | -0.0292388 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0292324 |
| GNAS | GNAS complex locus | -0.0288043 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0278925 |
| FHIT | fragile histidine triad | -0.0278573 |
| DENND1A | DENN/MADD domain containing 1A | -0.0276829 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0275657 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0275287 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0271217 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0270282 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0270225 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0269466 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0266379 |
| RAI14 | retinoic acid induced 14 | -0.0265744 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0260789 |
| RASAL2 | RAS protein activator like 2 | -0.0260188 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0258451 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0255908 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0253863 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0252133 |
| NAV1 | neuron navigator 1 | -0.0251153 |
| MT1X | metallothionein 1X | -0.0248569 |
| CAST | calpastatin | -0.0244955 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0244316 |
| VIM | vimentin | -0.0244079 |
| AEBP2 | AE binding protein 2 | -0.0243573 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0238455 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.023753 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237135 |
| NAV2 | neuron navigator 2 | -0.0231596 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0228305 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.02273 |
| EGFR | epidermal growth factor receptor | -0.0224229 |
| KALRN | kalirin, RhoGEF kinase | -0.0223676 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0222385 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0216104 |
| RPL26 | ribosomal protein L26 | -0.0215898 |
| PGK1 | phosphoglycerate kinase 1 | -0.0214356 |
| CUX1 | cut-like homeobox 1 | -0.0213435 |
| PLSCR1 | phospholipid scramblase 1 | -0.0211626 |
| NDRG1 | N-myc downstream regulated 1 | -0.0211462 |
