| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.194152 |
| FAT1 | FAT atypical cadherin 1 | 0.169113 |
| LOC112694756 | uncharaterized LOC112694756 | 0.093443 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0817427 |
| RPL3 | ribosomal protein L3 | 0.081508 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0770691 |
| MSI2 | musashi RNA-binding protein 2 | 0.0649582 |
| FLNB | filamin B, beta | 0.0649479 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0628566 |
| PRELID2 | PRELI domain containing 2 | 0.0607956 |
| EPHA2 | EPH receptor A2 | 0.0545476 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0536966 |
| RNF213 | ring finger protein 213 | 0.0535666 |
| HDLBP | high density lipoprotein binding protein | 0.0531194 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0510142 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0491549 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0486622 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0481156 |
| ASS1 | argininosuccinate synthase 1 | 0.0459181 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0424281 |
| MLEC | malectin | 0.0421221 |
| RPL13A | ribosomal protein L13a | 0.0410369 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0402711 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0399708 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038814 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0378539 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0375404 |
| RAD51B | RAD51 paralog B | 0.0361384 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.035811 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0356078 |
| AFDN | afadin, adherens junction formation factor | 0.0353878 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0345313 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0345172 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0336394 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0332597 |
| ACTN4 | actinin, alpha 4 | 0.0331955 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0330481 |
| ANXA11 | annexin A11 | 0.0329416 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.032847 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0326235 |
| PLEC | plectin | 0.0323794 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.032348 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0321982 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0316175 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0304634 |
| MYOF | myoferlin | 0.0304254 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0296008 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0294896 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0293244 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0292457 |
| HLA-C | major histocompatibility complex, class I, C | 0.0289975 |
| PYGB | phosphorylase, glycogen; brain | 0.0284711 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0284314 |
| ITGB4 | integrin, beta 4 | 0.0281472 |
| RACK1 | receptor for activated C kinase 1 | 0.0277413 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0274234 |
| NFIA | nuclear factor I/A | 0.0272556 |
| DENND1A | DENN/MADD domain containing 1A | 0.0267463 |
| CTBP2 | C-terminal binding protein 2 | 0.0266847 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0259562 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0259236 |
| LMNA | lamin A/C | 0.0254886 |
| RPS4X | ribosomal protein S4, X-linked | 0.0254605 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0251777 |
| SMAD3 | SMAD family member 3 | 0.0241988 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0240927 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.023986 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0237063 |
| PTEN | phosphatase and tensin homolog | 0.0231481 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0229315 |
| LAMB3 | laminin, beta 3 | 0.0229118 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.022402 |
| ANXA2 | annexin A2 | 0.0223142 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0222621 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0222015 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0221108 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0220194 |
| PCBP2 | poly(rC) binding protein 2 | 0.0218934 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0218535 |
| DNM2 | dynamin 2 | 0.0217889 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0217815 |
| NDRG1 | N-myc downstream regulated 1 | 0.0216711 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0216061 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0216035 |
| KIAA1671 | KIAA1671 | 0.0212244 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0212191 |
| TLN2 | talin 2 | 0.0211081 |
| SURF4 | surfeit 4 | 0.0209891 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0209711 |
| ACTG1 | actin gamma 1 | 0.0208118 |
| EXOC4 | exocyst complex component 4 | 0.0203801 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0201897 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0201297 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0199795 |
| YBX1 | Y box binding protein 1 | 0.0198015 |
| GSE1 | Gse1 coiled-coil protein | 0.0195315 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0194863 |
| ETNK1 | ethanolamine kinase 1 | 0.0194329 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0194226 |
| CDK19 | cyclin-dependent kinase 19 | 0.0192373 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.15717 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.153205 |
| LMO7 | LIM domain 7 | -0.133916 |
| RPS6 | ribosomal protein S6 | -0.122563 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.110757 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0998283 |
| MYO1E | myosin IE | -0.0984121 |
| PTMA | prothymosin, alpha | -0.0841497 |
| RPS2 | ribosomal protein S2 | -0.0705328 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0647237 |
| AREG | amphiregulin | -0.0633917 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0624554 |
| RPLP2 | ribosomal protein, large, P2 | -0.0603524 |
| RPLP1 | ribosomal protein, large, P1 | -0.0598692 |
| RPS27A | ribosomal protein S27a | -0.0580371 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0564703 |
| RPS23 | ribosomal protein S23 | -0.0557836 |
| RPS25 | ribosomal protein S25 | -0.055616 |
| RPS8 | ribosomal protein S8 | -0.0520905 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0496818 |
| RPL26 | ribosomal protein L26 | -0.0474386 |
| DSG2 | desmoglein 2 | -0.0452208 |
| RPS24 | ribosomal protein S24 | -0.0447031 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0438116 |
| FRMD5 | FERM domain containing 5 | -0.0430807 |
| RPS29 | ribosomal protein S29 | -0.042964 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0417792 |
| EZR | ezrin | -0.0394133 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0385865 |
| RPS12 | ribosomal protein S12 | -0.0380635 |
| RPL9 | ribosomal protein L9 | -0.0371397 |
| HLA-B | major histocompatibility complex, class I, B | -0.0365646 |
| RPL36A | ribosomal protein L36a | -0.036352 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0363198 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0358347 |
| RPL28 | ribosomal protein L28 | -0.0354669 |
| RPL32 | ribosomal protein L32 | -0.0347441 |
| RPS13 | ribosomal protein S13 | -0.0340051 |
| S100A10 | S100 calcium binding protein A10 | -0.0339675 |
| RPL38 | ribosomal protein L38 | -0.0339524 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0336637 |
| RPS15 | ribosomal protein S15 | -0.0333895 |
| RPL37A | ribosomal protein L37a | -0.0333693 |
| RIGI | RNA sensor RIG-I | -0.0333484 |
| MUC13 | mucin 13, cell surface associated | -0.03246 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0324137 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0317463 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0315757 |
| FBXO11 | F-box protein 11 | -0.031112 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.030934 |
| RPL31 | ribosomal protein L31 | -0.0309255 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.030159 |
| RPL7A | ribosomal protein L7a | -0.0291341 |
| ASPH | aspartate beta-hydroxylase | -0.0287695 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0283614 |
| RPS16 | ribosomal protein S16 | -0.0283359 |
| RPL8 | ribosomal protein L8 | -0.0279398 |
| RPL19 | ribosomal protein L19 | -0.0278636 |
| PKM | pyruvate kinase, muscle | -0.0274675 |
| IER3 | immediate early response 3 | -0.0273574 |
| RPS19 | ribosomal protein S19 | -0.0272516 |
| SP100 | SP100 nuclear antigen | -0.0272101 |
| JMJD1C | jumonji domain containing 1C | -0.0270825 |
| PRSS3 | protease, serine, 3 | -0.0262042 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0258447 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0257033 |
| RPS11 | ribosomal protein S11 | -0.0253364 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0251489 |
| SETD5 | SET domain containing 5 | -0.025014 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0248419 |
| CCNI | cyclin I | -0.0246439 |
| UBC | ubiquitin C | -0.024428 |
| FUS | FUS RNA binding protein | -0.0243996 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0243748 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0243704 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0241303 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.023534 |
| RNF145 | ring finger protein 145 | -0.023428 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0230146 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0227092 |
| NKTR | natural killer cell triggering receptor | -0.0224408 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0222265 |
| EREG | epiregulin | -0.0221231 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0220987 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0220678 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0218544 |
| XAF1 | XIAP associated factor 1 | -0.0217179 |
| CD2AP | CD2-associated protein | -0.0213629 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0212584 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0211817 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0211347 |
| VCL | vinculin | -0.0210882 |
| RPL15 | ribosomal protein L15 | -0.0210616 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0209786 |
| PERP | PERP, TP53 apoptosis effector | -0.0209347 |
| LAMA4 | laminin, alpha 4 | -0.0208331 |
| RAB10 | RAB10, member RAS oncogene family | -0.0206887 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.020685 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.020627 |
| RPS5 | ribosomal protein S5 | -0.0205687 |
