| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | 0.114354 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0962954 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0826572 |
| TMSB4X | thymosin beta 4, X-linked | 0.0765655 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.074641 |
| CENPF | centromere protein F, 350/400kDa | 0.0647288 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0548167 |
| HSPA8 | heat shock 70kDa protein 8 | 0.053848 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0506182 |
| YEATS2 | YEATS domain containing 2 | 0.0467409 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0462713 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0461436 |
| PRELID2 | PRELI domain containing 2 | 0.0451595 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0449326 |
| POTEF | POTE ankyrin domain family, member F | 0.0448721 |
| RPS12 | ribosomal protein S12 | 0.044145 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0437399 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0425548 |
| RPL37A | ribosomal protein L37a | 0.0423766 |
| RPL3 | ribosomal protein L3 | 0.0415285 |
| PLEC | plectin | 0.0413663 |
| YBX1 | Y box binding protein 1 | 0.0411513 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0408568 |
| RPL35A | ribosomal protein L35a | 0.0408252 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0401338 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0399764 |
| EZR | ezrin | 0.0393162 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0390751 |
| RPL37 | ribosomal protein L37 | 0.0386907 |
| RPS3 | ribosomal protein S3 | 0.037788 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0377032 |
| ACTG1 | actin gamma 1 | 0.03622 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0357172 |
| RPL36 | ribosomal protein L36 | 0.0354242 |
| LOXL2 | lysyl oxidase-like 2 | 0.0347483 |
| RACK1 | receptor for activated C kinase 1 | 0.0342424 |
| RPS19 | ribosomal protein S19 | 0.0340933 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.033787 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.032835 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0327777 |
| RPL27 | ribosomal protein L27 | 0.0317667 |
| RPL11 | ribosomal protein L11 | 0.0309919 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0309387 |
| FLNB | filamin B, beta | 0.0306493 |
| PODXL | podocalyxin-like | 0.030554 |
| RPL13A | ribosomal protein L13a | 0.0301803 |
| RPS4X | ribosomal protein S4, X-linked | 0.0298361 |
| NDRG1 | N-myc downstream regulated 1 | 0.0297672 |
| ENO1 | enolase 1, (alpha) | 0.0291542 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0286164 |
| TNS3 | tensin 3 | 0.028542 |
| RPL26 | ribosomal protein L26 | 0.0282336 |
| NAV2 | neuron navigator 2 | 0.0281844 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0281724 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0277686 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0275973 |
| ANKRD11 | ankyrin repeat domain 11 | 0.027432 |
| ARRDC3 | arrestin domain containing 3 | 0.0274285 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0271428 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0270933 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0270153 |
| PFKP | phosphofructokinase, platelet | 0.026751 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.026729 |
| RNF213 | ring finger protein 213 | 0.0266003 |
| CABIN1 | calcineurin binding protein 1 | 0.0265119 |
| XPO6 | exportin 6 | 0.0261069 |
| SET | SET nuclear proto-oncogene | 0.0261063 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0259936 |
| SLK | STE20-like kinase | 0.0258526 |
| TUBB | tubulin, beta class I | 0.0258482 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0256536 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0254124 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0250267 |
| CEP250 | centrosomal protein 250kDa | 0.0249447 |
| EFNA5 | ephrin-A5 | 0.024231 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0241415 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0239794 |
| HLA-C | major histocompatibility complex, class I, C | 0.0238452 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0237531 |
| DENND1A | DENN/MADD domain containing 1A | 0.023691 |
| DST | dystonin | 0.0236395 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0234806 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0233615 |
| RPL23 | ribosomal protein L23 | 0.0232568 |
| RPS17 | ribosomal protein S17 | 0.0230008 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0228868 |
| RPL12 | ribosomal protein L12 | 0.0227346 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0222396 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0222276 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0220028 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0219964 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0218184 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0217376 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0215702 |
| TPM3 | tropomyosin 3 | 0.0214578 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0213102 |
| ANXA2 | annexin A2 | 0.0210577 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0209635 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0209183 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0207779 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.441065 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.11908 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.116596 |
| VIM | vimentin | -0.104375 |
| PTMA | prothymosin, alpha | -0.0760889 |
| TP63 | tumor protein p63 | -0.0742083 |
| TXNRD1 | thioredoxin reductase 1 | -0.0724464 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.066719 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.056874 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0568265 |
| JMJD1C | jumonji domain containing 1C | -0.0541867 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0499007 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0493988 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0456105 |
| USP34 | ubiquitin specific peptidase 34 | -0.0425195 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0409065 |
| RIGI | RNA sensor RIG-I | -0.0406404 |
| UBC | ubiquitin C | -0.0404131 |
| TMEM41B | transmembrane protein 41B | -0.0394008 |
| VMP1 | vacuole membrane protein 1 | -0.0375075 |
| JUN | jun proto-oncogene | -0.0370208 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0369145 |
| CANX | calnexin | -0.0367622 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0345845 |
| MT2A | metallothionein 2A | -0.0341123 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0333768 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.033374 |
| EREG | epiregulin | -0.0333711 |
| SP100 | SP100 nuclear antigen | -0.0331826 |
| FBXO11 | F-box protein 11 | -0.0320752 |
| EGR1 | early growth response 1 | -0.0318436 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0317794 |
| MT1X | metallothionein 1X | -0.030916 |
| ANKRD28 | ankyrin repeat domain 28 | -0.03079 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0302903 |
| EMP1 | epithelial membrane protein 1 | -0.0301937 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0290955 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0290852 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0289317 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0286317 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0283056 |
| ERBIN | erbb2 interacting protein | -0.0281103 |
| BPTF | bromodomain PHD finger transcription factor | -0.0280016 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0278789 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0276669 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0271617 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0266935 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0266206 |
| CD44 | CD44 molecule (Indian blood group) | -0.0265258 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0265052 |
| RUNX1 | runt-related transcription factor 1 | -0.0263074 |
| NPAS2 | neuronal PAS domain protein 2 | -0.026146 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0261396 |
| TOP1 | topoisomerase (DNA) I | -0.0260616 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0259454 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0259327 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0251473 |
| RAB27B | RAB27B, member RAS oncogene family | -0.024693 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0246414 |
| CDK13 | cyclin-dependent kinase 13 | -0.0246377 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0244053 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0240231 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0236762 |
| YBX3 | Y box binding protein 3 | -0.0236528 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0228078 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0226518 |
| USP12 | ubiquitin specific peptidase 12 | -0.022636 |
| FUS | FUS RNA binding protein | -0.0225898 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0224584 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0222451 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0221169 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0219381 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0218888 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0217741 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0217135 |
| ZNF217 | zinc finger protein 217 | -0.0216583 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0216519 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0215996 |
| S100A10 | S100 calcium binding protein A10 | -0.0215505 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0214904 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0212021 |
| PMP22 | peripheral myelin protein 22 | -0.0209249 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0207621 |
| SETX | senataxin | -0.0206845 |
| NF1 | neurofibromin 1 | -0.0206364 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0206265 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0205162 |
| PLSCR1 | phospholipid scramblase 1 | -0.0205151 |
| SGMS2 | sphingomyelin synthase 2 | -0.0204984 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0204053 |
| WASF2 | WAS protein family, member 2 | -0.0203401 |
| BMERB1 | bMERB domain containing 1 | -0.0202489 |
| OSMR | oncostatin M receptor | -0.0200989 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0192343 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0191386 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0191077 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0189464 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0186903 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.018651 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0185338 |
