| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.238723 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.135217 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0799128 |
| NDRG1 | N-myc downstream regulated 1 | 0.0782726 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0760465 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0739578 |
| PLEC | plectin | 0.0732845 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.07294 |
| CES1 | carboxylesterase 1 | 0.0717535 |
| TXNRD1 | thioredoxin reductase 1 | 0.0589584 |
| FAM13A | family with sequence similarity 13, member A | 0.057898 |
| MKI67 | marker of proliferation Ki-67 | 0.0530503 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0510767 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0480241 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.045225 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0444879 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0426674 |
| ARRDC3 | arrestin domain containing 3 | 0.0422166 |
| NGLY1 | N-glycanase 1 | 0.0412882 |
| SMAD3 | SMAD family member 3 | 0.0392023 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0374626 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0369463 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0353456 |
| RUNX1 | runt-related transcription factor 1 | 0.035157 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0326778 |
| HDLBP | high density lipoprotein binding protein | 0.0319679 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0319422 |
| YEATS2 | YEATS domain containing 2 | 0.0304429 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0271763 |
| GPATCH2L | G patch domain containing 2-like | 0.0270256 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0265307 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0263911 |
| KIAA1217 | KIAA1217 | 0.0260038 |
| SLTM | SAFB-like, transcription modulator | 0.025782 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0250595 |
| SPAG9 | sperm associated antigen 9 | 0.0245285 |
| ANO6 | anoctamin 6 | 0.0244391 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0240706 |
| CUL4A | cullin 4A | 0.0240288 |
| ZNF638 | zinc finger protein 638 | 0.0232275 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.022958 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0223812 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0222172 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0218007 |
| EP300 | E1A binding protein p300 | 0.0216028 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0215137 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0212091 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0211632 |
| MYO1B | myosin IB | 0.0211482 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0206777 |
| SMTN | smoothelin | 0.0204163 |
| ZNF292 | zinc finger protein 292 | 0.0203825 |
| RPL3 | ribosomal protein L3 | 0.0201236 |
| ARCN1 | archain 1 | 0.0199219 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.019762 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0193881 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0192614 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0191793 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0191194 |
| WDR45B | WD repeat domain 45B | 0.018991 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0189831 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0188693 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0188489 |
| PYGL | phosphorylase, glycogen, liver | 0.0185399 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.018449 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0183854 |
| KLC1 | kinesin light chain 1 | 0.0181942 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.017992 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0178588 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.017741 |
| SUCO | SUN domain containing ossification factor | 0.0176841 |
| MCL1 | myeloid cell leukemia 1 | 0.0175652 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.01753 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0171399 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.017119 |
| RLIM | ring finger protein, LIM domain interacting | 0.0168394 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0168315 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0167231 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.0166932 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0166709 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0165706 |
| FNIP1 | folliculin interacting protein 1 | 0.0164547 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0164343 |
| ATP11A | ATPase, class VI, type 11A | 0.0163996 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0163355 |
| SP3 | Sp3 transcription factor | 0.0162968 |
| TPD52 | tumor protein D52 | 0.0161064 |
| C1D | C1D nuclear receptor corepressor | 0.0156951 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0156502 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0156018 |
| LAMC2 | laminin, gamma 2 | 0.0155548 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0154454 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0154201 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 | 0.015393 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0152507 |
| CDCP1 | CUB domain containing protein 1 | 0.0152159 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0151008 |
| FRY | furry homolog (Drosophila) | 0.0150773 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0150682 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0150132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.364706 |
| TMSB10 | thymosin beta 10 | -0.157131 |
| PTMA | prothymosin, alpha | -0.11002 |
| MT2A | metallothionein 2A | -0.0974142 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0866443 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0827187 |
| FTL | ferritin, light polypeptide | -0.0700694 |
| ACTG1 | actin gamma 1 | -0.0658454 |
| S100A10 | S100 calcium binding protein A10 | -0.0636202 |
| SEC61G | Sec61 gamma subunit | -0.0626369 |
| ASPH | aspartate beta-hydroxylase | -0.060294 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0601699 |
| RPL35A | ribosomal protein L35a | -0.0594256 |
| RPLP1 | ribosomal protein, large, P1 | -0.0524677 |
| RPS25 | ribosomal protein S25 | -0.047624 |
| RPS24 | ribosomal protein S24 | -0.0471141 |
| CST3 | cystatin C | -0.0463249 |
| RPS6 | ribosomal protein S6 | -0.0430308 |
| RPL31 | ribosomal protein L31 | -0.0421923 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0420721 |
| EGR1 | early growth response 1 | -0.041711 |
| RPS8 | ribosomal protein S8 | -0.0416409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0413227 |
| INTS6 | integrator complex subunit 6 | -0.0397925 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0391914 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0387148 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0384765 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0375629 |
| PKM | pyruvate kinase, muscle | -0.0374853 |
| AREG | amphiregulin | -0.0374186 |
| RPS3 | ribosomal protein S3 | -0.036 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0356577 |
| RPS27A | ribosomal protein S27a | -0.0352845 |
| RPL37A | ribosomal protein L37a | -0.0351704 |
| RPL34 | ribosomal protein L34 | -0.0351366 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0349743 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0332375 |
| RPS12 | ribosomal protein S12 | -0.0319512 |
| RPL19 | ribosomal protein L19 | -0.0314545 |
| CUX1 | cut-like homeobox 1 | -0.0314493 |
| B2M | beta-2-microglobulin | -0.0310579 |
| RPS23 | ribosomal protein S23 | -0.0308116 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0307352 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0298489 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0298009 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0297577 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0292429 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0292278 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0290646 |
| VCL | vinculin | -0.0289822 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0289797 |
| RPS29 | ribosomal protein S29 | -0.0288649 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0285147 |
| ENO1 | enolase 1, (alpha) | -0.028234 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0280078 |
| RPLP2 | ribosomal protein, large, P2 | -0.026999 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0268308 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.026785 |
| RPL8 | ribosomal protein L8 | -0.0266277 |
| GNAS | GNAS complex locus | -0.0265321 |
| S100A9 | S100 calcium binding protein A9 | -0.0264544 |
| CCND1 | cyclin D1 | -0.0263735 |
| KRT7 | keratin 7, type II | -0.0263709 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0263207 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0263038 |
| MYOF | myoferlin | -0.0261581 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0257922 |
| S100A11 | S100 calcium binding protein A11 | -0.0257652 |
| S100P | S100 calcium binding protein P | -0.0257438 |
| RPS19 | ribosomal protein S19 | -0.025573 |
| RPL9 | ribosomal protein L9 | -0.0254369 |
| TPM4 | tropomyosin 4 | -0.025373 |
| RPL23 | ribosomal protein L23 | -0.0252971 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0252858 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.025133 |
| RAB10 | RAB10, member RAS oncogene family | -0.0251179 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0248315 |
| WASF2 | WAS protein family, member 2 | -0.0247969 |
| HLA-B | major histocompatibility complex, class I, B | -0.0243668 |
| RPL11 | ribosomal protein L11 | -0.0243662 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0242162 |
| RPL12 | ribosomal protein L12 | -0.0238936 |
| LMO7 | LIM domain 7 | -0.0237661 |
| LDHA | lactate dehydrogenase A | -0.0236077 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0233525 |
| MT1X | metallothionein 1X | -0.0233012 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0232814 |
| IER3 | immediate early response 3 | -0.0232358 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0228211 |
| HOMER1 | homer scaffolding protein 1 | -0.0227445 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0227106 |
| CAV2 | caveolin 2 | -0.0225176 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0224318 |
| RPS14 | ribosomal protein S14 | -0.0223962 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0223825 |
| FUS | FUS RNA binding protein | -0.0223745 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0223313 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0219947 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0219448 |
| TOP1 | topoisomerase (DNA) I | -0.0218992 |
