| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.108543 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0921636 |
| FAM20C | family with sequence similarity 20, member C | 0.0756784 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0727913 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0724825 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0629152 |
| NDRG1 | N-myc downstream regulated 1 | 0.0605429 |
| PRELID2 | PRELI domain containing 2 | 0.0599737 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0573935 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0572407 |
| NAV2 | neuron navigator 2 | 0.0533459 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0493066 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0469044 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0426128 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0403801 |
| ANGPTL4 | angiopoietin-like 4 | 0.038758 |
| HSPA8 | heat shock 70kDa protein 8 | 0.036107 |
| EFNA5 | ephrin-A5 | 0.034255 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0332942 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0317624 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0317103 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0316179 |
| MYOF | myoferlin | 0.0315548 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0311516 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.029076 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.029038 |
| FAM13A | family with sequence similarity 13, member A | 0.0284505 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0280571 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0279132 |
| RUNX1 | runt-related transcription factor 1 | 0.0273763 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0269159 |
| YEATS2 | YEATS domain containing 2 | 0.0265581 |
| LOXL2 | lysyl oxidase-like 2 | 0.0256189 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0253718 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0251601 |
| NBAS | neuroblastoma amplified sequence | 0.0248497 |
| VEGFA | vascular endothelial growth factor A | 0.024524 |
| HLA-C | major histocompatibility complex, class I, C | 0.0245146 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0239451 |
| CEP250 | centrosomal protein 250kDa | 0.0238319 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0236722 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0233503 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0233211 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0229999 |
| RAD51B | RAD51 paralog B | 0.02231 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0218205 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0213216 |
| CLTC | clathrin, heavy chain (Hc) | 0.0209588 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0209548 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0202145 |
| ARRDC3 | arrestin domain containing 3 | 0.0199913 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0195534 |
| ANO6 | anoctamin 6 | 0.019411 |
| RPL3 | ribosomal protein L3 | 0.0193651 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0192848 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0192495 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0189291 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0188539 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0186393 |
| RUNX2 | runt-related transcription factor 2 | 0.0185971 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0184848 |
| RPL13A | ribosomal protein L13a | 0.0184451 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0184226 |
| EGFR | epidermal growth factor receptor | 0.0184081 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 | 0.0183812 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.018329 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0182792 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0182791 |
| PFKP | phosphofructokinase, platelet | 0.0181151 |
| SLTM | SAFB-like, transcription modulator | 0.018063 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0180595 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0180333 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0179256 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0178817 |
| ANXA2 | annexin A2 | 0.0176937 |
| FLNA | filamin A, alpha | 0.0175952 |
| CABIN1 | calcineurin binding protein 1 | 0.017545 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0169628 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0168498 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0167676 |
| ETV6 | ets variant 6 | 0.0166883 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0164978 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.0164564 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0163863 |
| RPL34 | ribosomal protein L34 | 0.0163568 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0163234 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0162535 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0162405 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0160551 |
| GOLGA2 | golgin A2 | 0.015793 |
| FBXO32 | F-box protein 32 | 0.0156748 |
| ARCN1 | archain 1 | 0.0156716 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0155045 |
| NGLY1 | N-glycanase 1 | 0.0154672 |
| AFAP1 | actin filament associated protein 1 | 0.0154014 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0152753 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0151663 |
| HDLBP | high density lipoprotein binding protein | 0.0151439 |
| INTS1 | integrator complex subunit 1 | 0.0151278 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0150897 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.321631 |
| VIM | vimentin | -0.193202 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.132267 |
| CD44 | CD44 molecule (Indian blood group) | -0.114143 |
| PTMA | prothymosin, alpha | -0.104809 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0883789 |
| PCBP2 | poly(rC) binding protein 2 | -0.0794422 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0785597 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0777492 |
| TMSB10 | thymosin beta 10 | -0.0729242 |
| UBC | ubiquitin C | -0.0726691 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0706702 |
| GLCCI1 | glucocorticoid induced 1 | -0.0678966 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0647537 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0605629 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0529378 |
| ENO1 | enolase 1, (alpha) | -0.0523519 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0522418 |
| FTL | ferritin, light polypeptide | -0.0514139 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.050261 |
| MT2A | metallothionein 2A | -0.046066 |
| USP34 | ubiquitin specific peptidase 34 | -0.0431832 |
| ASPH | aspartate beta-hydroxylase | -0.0429503 |
| CANX | calnexin | -0.0426151 |
| NRG1 | neuregulin 1 | -0.04233 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0419847 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0413409 |
| MAP1B | microtubule-associated protein 1B | -0.0392623 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0388416 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0387507 |
| S100A10 | S100 calcium binding protein A10 | -0.0387272 |
| GOLGA4 | golgin A4 | -0.0384976 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0380422 |
| SETD5 | SET domain containing 5 | -0.0377543 |
| LOX | lysyl oxidase | -0.0377064 |
| MEF2A | myocyte enhancer factor 2A | -0.037547 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0375176 |
| PKM | pyruvate kinase, muscle | -0.0375155 |
| CDH13 | cadherin 13 | -0.037462 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0372802 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0368925 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0365734 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0365003 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0357592 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0343203 |
| RIOK3 | RIO kinase 3 | -0.0342538 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0336215 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0333897 |
| JMJD1C | jumonji domain containing 1C | -0.0333036 |
| CLIC4 | chloride intracellular channel 4 | -0.0330059 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0324311 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0316077 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.031332 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0311351 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0310345 |
| FBXO11 | F-box protein 11 | -0.0307367 |
| TXNRD1 | thioredoxin reductase 1 | -0.0307275 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0303544 |
| FN1 | fibronectin 1 | -0.0302446 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0301835 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0301605 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0301174 |
| WASF2 | WAS protein family, member 2 | -0.0300829 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0299601 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0298203 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0298166 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0297624 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0295859 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0295411 |
| CUX1 | cut-like homeobox 1 | -0.0295028 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.029265 |
| RPS25 | ribosomal protein S25 | -0.0289458 |
| CCDC88A | coiled-coil domain containing 88A | -0.0289357 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0288976 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0288877 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0283415 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0281998 |
| ERBIN | erbb2 interacting protein | -0.0280871 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.027935 |
| CLMP | CXADR-like membrane protein | -0.027883 |
| B2M | beta-2-microglobulin | -0.0276758 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0276529 |
| SYAP1 | synapse associated protein 1 | -0.0275542 |
| PARD3 | par-3 family cell polarity regulator | -0.0274213 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0273077 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0272084 |
| VMP1 | vacuole membrane protein 1 | -0.0271892 |
| TMEM263 | transmembrane protein 263 | -0.0270697 |
| EGR1 | early growth response 1 | -0.0269122 |
| NRP1 | neuropilin 1 | -0.0267007 |
| NTN4 | netrin 4 | -0.0266817 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0265015 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0262933 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0262722 |
| TAOK1 | TAO kinase 1 | -0.0261913 |
| COPA | coatomer protein complex, subunit alpha | -0.0260358 |
| VCL | vinculin | -0.0257617 |
| SYT1 | synaptotagmin I | -0.0256696 |
| DPYD | dihydropyrimidine dehydrogenase | -0.02566 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0255432 |
