| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.245319 |
| NDRG1 | N-myc downstream regulated 1 | 0.203287 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.141159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.116655 |
| PLEC | plectin | 0.0766806 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0742698 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0692587 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0687435 |
| ARRDC3 | arrestin domain containing 3 | 0.0671732 |
| HSPA8 | heat shock 70kDa protein 8 | 0.062531 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0542634 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0523728 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0522769 |
| RACK1 | receptor for activated C kinase 1 | 0.048841 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0479194 |
| FAM13A | family with sequence similarity 13, member A | 0.0472561 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0451244 |
| TFG | TRK-fused gene | 0.0434156 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0431333 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0427925 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0426726 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0417499 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0402692 |
| HMGB2 | high mobility group box 2 | 0.0400854 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0360321 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0354969 |
| RPS3 | ribosomal protein S3 | 0.0353833 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0347243 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0345681 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0343019 |
| CALR | calreticulin | 0.0340724 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0329767 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0329612 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0325745 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0324963 |
| HLA-C | major histocompatibility complex, class I, C | 0.0320847 |
| FLNA | filamin A, alpha | 0.0311891 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0307753 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0301531 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0291983 |
| MATR3 | matrin 3 | 0.0291559 |
| ANXA5 | annexin A5 | 0.0286132 |
| RPL3 | ribosomal protein L3 | 0.028605 |
| YBX1 | Y box binding protein 1 | 0.0273596 |
| HMGA1 | high mobility group AT-hook 1 | 0.0266484 |
| RHOA | ras homolog family member A | 0.0262721 |
| ANXA2 | annexin A2 | 0.0255985 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0250518 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.024919 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0247693 |
| NUP58 | nucleoporin 58 | 0.0245161 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0243062 |
| VEGFA | vascular endothelial growth factor A | 0.0240642 |
| RNF145 | ring finger protein 145 | 0.0240131 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0235407 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.023373 |
| USP3 | ubiquitin specific peptidase 3 | 0.023148 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0225214 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0224289 |
| TXNRD1 | thioredoxin reductase 1 | 0.021876 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0218307 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0216971 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0216543 |
| FOSL1 | FOS-like antigen 1 | 0.0216285 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0215353 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0214176 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0213801 |
| RPL30 | ribosomal protein L30 | 0.0212703 |
| ECT2 | epithelial cell transforming 2 | 0.0210591 |
| TFRC | transferrin receptor | 0.0208682 |
| TPM3 | tropomyosin 3 | 0.0208471 |
| RPL7 | ribosomal protein L7 | 0.0207336 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0206895 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0205739 |
| RPL11 | ribosomal protein L11 | 0.0205329 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0204216 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0203756 |
| PCBP2 | poly(rC) binding protein 2 | 0.020342 |
| MSN | moesin | 0.0203204 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0201921 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0200705 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0198982 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0197708 |
| CDC73 | cell division cycle 73 | 0.0197672 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0197602 |
| NCKAP1 | NCK-associated protein 1 | 0.0196652 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0195438 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.019528 |
| RLF | rearranged L-myc fusion | 0.0194254 |
| CENPF | centromere protein F, 350/400kDa | 0.0192898 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.019257 |
| RPS4X | ribosomal protein S4, X-linked | 0.0190356 |
| TSPAN15 | tetraspanin 15 | 0.0189803 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0187227 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0184997 |
| TAGLN2 | transgelin 2 | 0.0182541 |
| RPLP0 | ribosomal protein, large, P0 | 0.0180941 |
| NAV2 | neuron navigator 2 | 0.0180062 |
| PEG10 | paternally expressed 10 | 0.0179997 |
| ZNF292 | zinc finger protein 292 | 0.0179754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.212829 |
| PTMA | prothymosin, alpha | -0.187567 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.187184 |
| FTL | ferritin, light polypeptide | -0.159988 |
| EXT1 | exostosin glycosyltransferase 1 | -0.111495 |
| FBXO32 | F-box protein 32 | -0.0947249 |
| TMSB10 | thymosin beta 10 | -0.0915364 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0908072 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.087665 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0868066 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0800107 |
| EFNA5 | ephrin-A5 | -0.076527 |
| ERBIN | erbb2 interacting protein | -0.0684234 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.064607 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0641635 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0622067 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0611151 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.059729 |
| LMO7 | LIM domain 7 | -0.0596754 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.058248 |
| CD2AP | CD2-associated protein | -0.0576992 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0558146 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0530235 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0528449 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0517954 |
| MYO6 | myosin VI | -0.0513926 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0513254 |
| S100A10 | S100 calcium binding protein A10 | -0.0497214 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.048821 |
| HLA-B | major histocompatibility complex, class I, B | -0.0487378 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.047039 |
| RNF213 | ring finger protein 213 | -0.046057 |
| MAP1B | microtubule-associated protein 1B | -0.0458307 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0453678 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0443927 |
| MX2 | MX dynamin-like GTPase 2 | -0.044274 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0431533 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.043143 |
| RAI14 | retinoic acid induced 14 | -0.0414681 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0414021 |
| RBM47 | RNA binding motif protein 47 | -0.0404912 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0404401 |
| TPM4 | tropomyosin 4 | -0.0403775 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0398262 |
| MYO1E | myosin IE | -0.039782 |
| RPS29 | ribosomal protein S29 | -0.0395402 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0394654 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0394441 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0394114 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0393842 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0390031 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0389382 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0379127 |
| VCL | vinculin | -0.0377231 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0371438 |
| MAP4 | microtubule-associated protein 4 | -0.0370711 |
| RASAL2 | RAS protein activator like 2 | -0.0366022 |
| GOLGB1 | golgin B1 | -0.0358101 |
| TMEM165 | transmembrane protein 165 | -0.0357135 |
| FRMD5 | FERM domain containing 5 | -0.0356605 |
| MCU | mitochondrial calcium uniporter | -0.0354338 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0351767 |
| RPS23 | ribosomal protein S23 | -0.0350116 |
| ETV6 | ets variant 6 | -0.0349675 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0348636 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0345415 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0344292 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0344246 |
| HLA-A | major histocompatibility complex, class I, A | -0.0338074 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0337275 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0333555 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0330826 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0330201 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0328911 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0327355 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0326912 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0325712 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0325285 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0324528 |
| CSTB | cystatin B (stefin B) | -0.0322518 |
| ATXN1 | ataxin 1 | -0.0319896 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0319519 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0311938 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0309722 |
| RPLP2 | ribosomal protein, large, P2 | -0.0307992 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0307671 |
| CCND1 | cyclin D1 | -0.0306889 |
| RIGI | RNA sensor RIG-I | -0.0306563 |
| WASF2 | WAS protein family, member 2 | -0.0306503 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0304924 |
| BPTF | bromodomain PHD finger transcription factor | -0.0299147 |
| NF1 | neurofibromin 1 | -0.0298598 |
| H1-0 | H1.0 linker histone | -0.0298153 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.02978 |
| VIM | vimentin | -0.0296922 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0293746 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0292918 |
| CUX1 | cut-like homeobox 1 | -0.0289598 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0289278 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0288545 |
