| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.122014 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0977915 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0788739 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0780795 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0752669 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0741681 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0729743 |
| CTSL | cathepsin L | 0.071669 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0616614 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0614372 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0603025 |
| FN1 | fibronectin 1 | 0.0599305 |
| FLNA | filamin A, alpha | 0.0598464 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0595432 |
| TBXT | T-box transcription factor T | 0.0581443 |
| NDRG1 | N-myc downstream regulated 1 | 0.0571665 |
| CDH13 | cadherin 13 | 0.0523269 |
| RTN4 | reticulon 4 | 0.0518814 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0516646 |
| TXNRD1 | thioredoxin reductase 1 | 0.0512217 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0505698 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0493831 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0484562 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0478278 |
| RPL3 | ribosomal protein L3 | 0.0462187 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0461314 |
| EFNA5 | ephrin-A5 | 0.0446739 |
| ASPH | aspartate beta-hydroxylase | 0.0445529 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0439089 |
| GRAMD1B | GRAM domain containing 1B | 0.0427945 |
| ANXA2 | annexin A2 | 0.0421531 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0405918 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0402146 |
| RPS23 | ribosomal protein S23 | 0.0401145 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0391402 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0377967 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0377747 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0375066 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.036675 |
| PCBP2 | poly(rC) binding protein 2 | 0.0360061 |
| CTBP2 | C-terminal binding protein 2 | 0.0359674 |
| RPS24 | ribosomal protein S24 | 0.035961 |
| FLNB | filamin B, beta | 0.0357004 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0356279 |
| TPM3 | tropomyosin 3 | 0.0354682 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0349493 |
| MSN | moesin | 0.0345939 |
| UBC | ubiquitin C | 0.0342656 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0341699 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0339744 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0330456 |
| PTK2 | protein tyrosine kinase 2 | 0.0328845 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0328602 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.031562 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0312947 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0310545 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0310298 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0309785 |
| HLA-B | major histocompatibility complex, class I, B | 0.0307892 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0305907 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0302565 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0301318 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0291878 |
| AHR | aryl hydrocarbon receptor | 0.0286801 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0284911 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.028374 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0280806 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0279971 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0278974 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0278766 |
| EZR | ezrin | 0.027572 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0270121 |
| FAT1 | FAT atypical cadherin 1 | 0.0268985 |
| NBAS | neuroblastoma amplified sequence | 0.0267528 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0267496 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0259913 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0259622 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0259401 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0257449 |
| DENND1A | DENN/MADD domain containing 1A | 0.0252888 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0248222 |
| NRCAM | neuronal cell adhesion molecule | 0.0248147 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0246735 |
| SP3 | Sp3 transcription factor | 0.0245795 |
| STC2 | stanniocalcin 2 | 0.0241807 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0240989 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0240709 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0240418 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0237399 |
| PDE10A | phosphodiesterase 10A | 0.0236235 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0235128 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0234637 |
| NCAM1 | neural cell adhesion molecule 1 | 0.023458 |
| LAMA5 | laminin, alpha 5 | 0.0232849 |
| PKM | pyruvate kinase, muscle | 0.0232509 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0232301 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0232246 |
| PLEC | plectin | 0.0231353 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.023105 |
| POTEF | POTE ankyrin domain family, member F | 0.0230463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.31018 |
| TMSB10 | thymosin beta 10 | -0.139684 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.115127 |
| KYNU | kynureninase | -0.103481 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0845001 |
| FTL | ferritin, light polypeptide | -0.084454 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0837521 |
| MT2A | metallothionein 2A | -0.0811611 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0804444 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0727999 |
| S100A6 | S100 calcium binding protein A6 | -0.0598613 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0591968 |
| RPL12 | ribosomal protein L12 | -0.0568379 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0551856 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0473067 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0462891 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0460025 |
| GNAS | GNAS complex locus | -0.0453608 |
| SMAD2 | SMAD family member 2 | -0.0449708 |
| RPL23 | ribosomal protein L23 | -0.0442582 |
| RPL35A | ribosomal protein L35a | -0.0430069 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0426093 |
| DST | dystonin | -0.0415519 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0401355 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0397996 |
| YBX3 | Y box binding protein 3 | -0.0390763 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0389661 |
| RGS2 | regulator of G-protein signaling 2 | -0.0389509 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0383355 |
| RPS12 | ribosomal protein S12 | -0.038242 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0371087 |
| RPS6 | ribosomal protein S6 | -0.0369031 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0367156 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0365025 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0364747 |
| GDA | guanine deaminase | -0.0359446 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0353648 |
| MT1X | metallothionein 1X | -0.0343089 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0340862 |
| RPL18 | ribosomal protein L18 | -0.034012 |
| NF1 | neurofibromin 1 | -0.0337503 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0335532 |
| RACK1 | receptor for activated C kinase 1 | -0.0334299 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0334238 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.032705 |
| RTN1 | reticulon 1 | -0.0318591 |
| RPL19 | ribosomal protein L19 | -0.0317139 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0307418 |
| NTN4 | netrin 4 | -0.029612 |
| RPS19 | ribosomal protein S19 | -0.0295189 |
| RPL35 | ribosomal protein L35 | -0.0291611 |
| VIM | vimentin | -0.0291186 |
| RPL5 | ribosomal protein L5 | -0.0287621 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0287614 |
| RPL26 | ribosomal protein L26 | -0.0286624 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.028488 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0283685 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0278547 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0278151 |
| RPS3 | ribosomal protein S3 | -0.0277051 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0275909 |
| MAP7 | microtubule-associated protein 7 | -0.0273589 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0263241 |
| PHF14 | PHD finger protein 14 | -0.0262876 |
| EPHA4 | EPH receptor A4 | -0.0258137 |
| CHL1 | cell adhesion molecule L1-like | -0.0257424 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0256815 |
| RPS27 | ribosomal protein S27 | -0.0254051 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0253435 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0252809 |
| RPL34 | ribosomal protein L34 | -0.0251321 |
| CTSC | cathepsin C | -0.0251113 |
| RPS2 | ribosomal protein S2 | -0.0248639 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0248345 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.024376 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0241284 |
| ACTG1 | actin gamma 1 | -0.0239776 |
| PFN1 | profilin 1 | -0.0235686 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.0235081 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0230262 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0225568 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0223739 |
| KIAA0825 | KIAA0825 | -0.022318 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0222323 |
| RPS14 | ribosomal protein S14 | -0.0218793 |
| TBCA | tubulin folding cofactor A | -0.0213768 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0212988 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0212332 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.020978 |
| RPS27A | ribosomal protein S27a | -0.0205856 |
| UBXN4 | UBX domain protein 4 | -0.0203101 |
| COL5A2 | collagen, type V, alpha 2 | -0.0199886 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0199629 |
| MORF4L2 | mortality factor 4 like 2 | -0.0199424 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0194689 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0190924 |
| RPL7 | ribosomal protein L7 | -0.0188098 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0184701 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0183105 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0180898 |
