| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.117479 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0972782 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0942103 |
| PEG10 | paternally expressed 10 | 0.0882277 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0838176 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0789268 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.077902 |
| ENAH | enabled homolog (Drosophila) | 0.0776488 |
| DST | dystonin | 0.0763357 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0708767 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0705372 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0697673 |
| ITGAV | integrin, alpha V | 0.0681159 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0644091 |
| NCKAP1 | NCK-associated protein 1 | 0.0565533 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0522049 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0519771 |
| RHOH | ras homolog family member H | 0.0519563 |
| GPC3 | glypican 3 | 0.0510393 |
| RPL3 | ribosomal protein L3 | 0.0501488 |
| COL1A2 | collagen, type I, alpha 2 | 0.0499114 |
| TPM3 | tropomyosin 3 | 0.0490919 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0473483 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0467668 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0465792 |
| FOXP2 | forkhead box P2 | 0.0463869 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0459851 |
| ZNF292 | zinc finger protein 292 | 0.0455136 |
| POTEF | POTE ankyrin domain family, member F | 0.0448684 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0441371 |
| USP3 | ubiquitin specific peptidase 3 | 0.0430861 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0427428 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0426191 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0412114 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0409141 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0407277 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0404895 |
| TMSB4X | thymosin beta 4, X-linked | 0.0401402 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0394359 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0393686 |
| MTF2 | metal response element binding transcription factor 2 | 0.038965 |
| YBX1 | Y box binding protein 1 | 0.0384766 |
| NONO | non-POU domain containing, octamer-binding | 0.0378435 |
| PRRC2A | proline-rich coiled-coil 2A | 0.03747 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0374511 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0371687 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0364177 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0362753 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0352121 |
| SET | SET nuclear proto-oncogene | 0.0350963 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0349885 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0349262 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0348498 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0347101 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0345134 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0342583 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.034004 |
| CENPF | centromere protein F, 350/400kDa | 0.0338263 |
| ANXA1 | annexin A1 | 0.0337198 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0334851 |
| ZNF608 | zinc finger protein 608 | 0.0333719 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0333514 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0332874 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0331554 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0331472 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0331434 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0330112 |
| SP3 | Sp3 transcription factor | 0.0327982 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0327838 |
| FLNA | filamin A, alpha | 0.032476 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0324513 |
| PDGFC | platelet derived growth factor C | 0.0321687 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0320993 |
| MED12L | mediator complex subunit 12-like | 0.0320836 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0320156 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0318886 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.031664 |
| ACTN4 | actinin, alpha 4 | 0.031648 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0310792 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0307191 |
| THBS1 | thrombospondin 1 | 0.0304176 |
| CALR | calreticulin | 0.0302584 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0294506 |
| CALU | calumenin | 0.0294087 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293596 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0292267 |
| FAT1 | FAT atypical cadherin 1 | 0.0291664 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0291386 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0290835 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0288051 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0285533 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0283078 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0278206 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0273555 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0273215 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0270735 |
| TENM2 | teneurin transmembrane protein 2 | 0.0269569 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0268694 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0266722 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0266383 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141733 |
| PTMA | prothymosin, alpha | -0.133903 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13312 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.12309 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.105953 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0991977 |
| CADM2 | cell adhesion molecule 2 | -0.0785829 |
| AHNAK | AHNAK nucleoprotein | -0.0664816 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0639544 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0621444 |
| H1-0 | H1.0 linker histone | -0.0587403 |
| TMSB10 | thymosin beta 10 | -0.0586343 |
| RPL19 | ribosomal protein L19 | -0.0539129 |
| VIM | vimentin | -0.0534851 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0444335 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0442077 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0435473 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0434048 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0425994 |
| CUX1 | cut-like homeobox 1 | -0.0425122 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0421797 |
| RSF1 | remodeling and spacing factor 1 | -0.041952 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0405262 |
| HMGB1 | high mobility group box 1 | -0.040143 |
| RAD51B | RAD51 paralog B | -0.0399876 |
| JMJD1C | jumonji domain containing 1C | -0.0398312 |
| NHSL1 | NHS-like 1 | -0.0392395 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0387717 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0385721 |
| RPL31 | ribosomal protein L31 | -0.0380327 |
| SETD5 | SET domain containing 5 | -0.0365407 |
| RPS8 | ribosomal protein S8 | -0.0364105 |
| GPHN | gephyrin | -0.0353531 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0347285 |
| PHIP | pleckstrin homology domain interacting protein | -0.0343019 |
| RDX | radixin | -0.0339211 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0336924 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0335632 |
| RPL35A | ribosomal protein L35a | -0.0331853 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326275 |
| FN1 | fibronectin 1 | -0.0318308 |
| SGO2 | shugoshin 2 | -0.0316934 |
| SBF2 | SET binding factor 2 | -0.0314198 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0313434 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0309621 |
| BBX | bobby sox homolog (Drosophila) | -0.0302336 |
| FTL | ferritin, light polypeptide | -0.0301784 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0301215 |
| AK1 | adenylate kinase 1 | -0.0299195 |
| USP34 | ubiquitin specific peptidase 34 | -0.0296154 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.029504 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0294227 |
| RPLP0 | ribosomal protein, large, P0 | -0.0293117 |
| NDRG1 | N-myc downstream regulated 1 | -0.0292537 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0287644 |
| RPL28 | ribosomal protein L28 | -0.0286539 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.028372 |
| NOP58 | NOP58 ribonucleoprotein | -0.0282435 |
| RPS25 | ribosomal protein S25 | -0.0279682 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0277134 |
| NRG1 | neuregulin 1 | -0.0276869 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0273419 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0263339 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0261576 |
| TOX | thymocyte selection-associated high mobility group box | -0.0260887 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0258002 |
| NXN | nucleoredoxin | -0.0256533 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0255363 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0253544 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0252583 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0250644 |
| TAOK1 | TAO kinase 1 | -0.0249647 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0248216 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.024743 |
| COL3A1 | collagen, type III, alpha 1 | -0.024671 |
| RPS21 | ribosomal protein S21 | -0.0243664 |
| MT2A | metallothionein 2A | -0.0243632 |
| ASPH | aspartate beta-hydroxylase | -0.024341 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0241755 |
| PCDH17 | protocadherin 17 | -0.0241662 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0240481 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0239849 |
| GOLGA4 | golgin A4 | -0.0239601 |
| SNX6 | sorting nexin 6 | -0.0239445 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0237646 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0237386 |
| PCDH7 | protocadherin 7 | -0.023632 |
| BPTF | bromodomain PHD finger transcription factor | -0.0236174 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.02338 |
| SMYD3 | SET and MYND domain containing 3 | -0.0233782 |
| RPS16 | ribosomal protein S16 | -0.023111 |
| EFNA5 | ephrin-A5 | -0.0230075 |
| KIAA1958 | KIAA1958 | -0.023007 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0229708 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0229308 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0228691 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0227645 |
| N4BP2 | NEDD4 binding protein 2 | -0.0227339 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.022658 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0226084 |
