| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTN4 | actinin, alpha 4 | 0.0825823 |
| VCL | vinculin | 0.079885 |
| AHNAK | AHNAK nucleoprotein | 0.0768552 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0725786 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0724232 |
| VIM | vimentin | 0.0621572 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0596961 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0493754 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0475897 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0469576 |
| PLEC | plectin | 0.0468141 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0397606 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0393402 |
| FLNA | filamin A, alpha | 0.0334304 |
| EGR1 | early growth response 1 | 0.0321489 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0319368 |
| RPS24 | ribosomal protein S24 | 0.0319281 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0311713 |
| RNF213 | ring finger protein 213 | 0.0307273 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0279222 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0270306 |
| NAV2 | neuron navigator 2 | 0.0259116 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0256463 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0253786 |
| EGFR | epidermal growth factor receptor | 0.0253291 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0252976 |
| TNS3 | tensin 3 | 0.0246057 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0239291 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0234165 |
| TUBB | tubulin, beta class I | 0.022542 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0223311 |
| HMGA2 | high mobility group AT-hook 2 | 0.0220036 |
| CMIP | c-Maf inducing protein | 0.0210681 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0208095 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.0199558 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0198155 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0196342 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0190815 |
| HDLBP | high density lipoprotein binding protein | 0.0184578 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0181535 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0181405 |
| CTSD | cathepsin D | 0.017479 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0173615 |
| FHL2 | four and a half LIM domains 2 | 0.0171433 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0170638 |
| CD109 | CD109 molecule | 0.0168702 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0167484 |
| SEPTIN9 | septin 9 | 0.0167026 |
| CD59 | CD59 molecule, complement regulatory protein | 0.016631 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0161481 |
| CAVIN1 | caveolae associated protein 1 | 0.01591 |
| ATG7 | autophagy related 7 | 0.015876 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0156767 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0155899 |
| MCL1 | myeloid cell leukemia 1 | 0.0150834 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0150015 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0148593 |
| IER3 | immediate early response 3 | 0.0147783 |
| MYO1E | myosin IE | 0.0142712 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0137243 |
| JUN | jun proto-oncogene | 0.0135469 |
| KLF6 | Kruppel-like factor 6 | 0.0135304 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0133843 |
| ACTN1 | actinin, alpha 1 | 0.0133616 |
| ZNF546 | zinc finger protein 546 | 0.0132908 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0132749 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0132103 |
| RASAL2 | RAS protein activator like 2 | 0.0131491 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.012996 |
| MYO10 | myosin X | 0.0128387 |
| NEK6 | NIMA-related kinase 6 | 0.0127587 |
| RPLP1 | ribosomal protein, large, P1 | 0.0125699 |
| L1CAM | L1 cell adhesion molecule | 0.0123317 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.0122992 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0122323 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0121224 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.012013 |
| CANT1 | calcium activated nucleotidase 1 | 0.0120035 |
| KRT18 | keratin 18, type I | 0.0119102 |
| RNF220 | ring finger protein 220 | 0.0117895 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0117178 |
| PRSS23 | protease, serine, 23 | 0.0114878 |
| ZYX | zyxin | 0.0114461 |
| TMSB10 | thymosin beta 10 | 0.0113856 |
| RPLP0 | ribosomal protein, large, P0 | 0.0113649 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0113513 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0113388 |
| AGO1 | argonaute RISC catalytic component 1 | 0.0112474 |
| ARRB1 | arrestin, beta 1 | 0.0112461 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0112349 |
| PRDM16 | PR domain containing 16 | 0.0111983 |
| RAB7A | RAB7A, member RAS oncogene family | 0.011139 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0111006 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0110594 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0108104 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.0108001 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.0107862 |
| FASN | fatty acid synthase | 0.0107703 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0107626 |
| DLL3 | delta-like 3 (Drosophila) | 0.0106964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.169112 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.105339 |
| ZFP36 | ZFP36 ring finger protein | -0.0980126 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0977057 |
| RPS2 | ribosomal protein S2 | -0.0894069 |
| JMJD1C | jumonji domain containing 1C | -0.0879536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0826852 |
| RPS16 | ribosomal protein S16 | -0.0810977 |
| CENPF | centromere protein F, 350/400kDa | -0.0810656 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0800631 |
| PTMA | prothymosin, alpha | -0.0731078 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0694935 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0651452 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0649272 |
| RPS12 | ribosomal protein S12 | -0.0642318 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0627603 |
| TXNRD1 | thioredoxin reductase 1 | -0.0615691 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.061404 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0607988 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.060588 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0597696 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0589733 |
| ZNF292 | zinc finger protein 292 | -0.0586621 |
| DSTN | destrin (actin depolymerizing factor) | -0.0575965 |
| ASPH | aspartate beta-hydroxylase | -0.0560344 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0534149 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0531138 |
| CDK19 | cyclin-dependent kinase 19 | -0.0528352 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0527051 |
| SPAG9 | sperm associated antigen 9 | -0.0521451 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0518391 |
| SBF2 | SET binding factor 2 | -0.0518233 |
| MT2A | metallothionein 2A | -0.049762 |
| SEPTIN7 | septin 7 | -0.0497303 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0492333 |
| USP34 | ubiquitin specific peptidase 34 | -0.048778 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0467859 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.04618 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0452878 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0451438 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0447522 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0442562 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.044142 |
| ANLN | anillin, actin binding protein | -0.0437396 |
| GOLGA4 | golgin A4 | -0.0432582 |
| RPL37A | ribosomal protein L37a | -0.0429333 |
| RPL7 | ribosomal protein L7 | -0.0426621 |
| ARRDC3 | arrestin domain containing 3 | -0.0419311 |
| VMP1 | vacuole membrane protein 1 | -0.0418529 |
| SNX14 | sorting nexin 14 | -0.0415453 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0413466 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0413005 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0412287 |
| SETD5 | SET domain containing 5 | -0.0411792 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0403249 |
| RPS6 | ribosomal protein S6 | -0.0402774 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0401758 |
| BRD2 | bromodomain containing 2 | -0.0400517 |
| WASF2 | WAS protein family, member 2 | -0.0391669 |
| SMAD3 | SMAD family member 3 | -0.0388476 |
| GLCCI1 | glucocorticoid induced 1 | -0.038537 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0380287 |
| TPX2 | TPX2, microtubule-associated | -0.037816 |
| MKI67 | marker of proliferation Ki-67 | -0.0376968 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0376189 |
| IPO7 | importin 7 | -0.0368954 |
| THOC2 | THO complex 2 | -0.0368249 |
| NKTR | natural killer cell triggering receptor | -0.0364332 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -0.0363569 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0352797 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0348822 |
| FBL | fibrillarin | -0.0345962 |
| RBM39 | RNA binding motif protein 39 | -0.0345645 |
| SET | SET nuclear proto-oncogene | -0.0344165 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0342271 |
| PTEN | phosphatase and tensin homolog | -0.03414 |
| B2M | beta-2-microglobulin | -0.0341135 |
| YAP1 | Yes-associated protein 1 | -0.0339988 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0339951 |
| RSF1 | remodeling and spacing factor 1 | -0.0339917 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0338574 |
| RPL21 | ribosomal protein L21 | -0.0338239 |
| RBM25 | RNA binding motif protein 25 | -0.0332584 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0332546 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0329249 |
| PKN2 | protein kinase N2 | -0.0329176 |
| YBX1 | Y box binding protein 1 | -0.0328386 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0325903 |
| UBXN4 | UBX domain protein 4 | -0.0325761 |
| CCDC88A | coiled-coil domain containing 88A | -0.0322104 |
| RDX | radixin | -0.0321699 |
| MATR3 | matrin 3 | -0.032146 |
| RPS8 | ribosomal protein S8 | -0.0319063 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0319034 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0316394 |
| FTL | ferritin, light polypeptide | -0.0313723 |
| TPR | translocated promoter region, nuclear basket protein | -0.0312669 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0311387 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0307075 |
| PCBP2 | poly(rC) binding protein 2 | -0.0305189 |
