| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.195746 |
| MYO6 | myosin VI | 0.0782099 |
| NDRG1 | N-myc downstream regulated 1 | 0.0767547 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0701494 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0690411 |
| PLEC | plectin | 0.0675586 |
| NAV2 | neuron navigator 2 | 0.064953 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0594086 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.056608 |
| LOC112694756 | uncharaterized LOC112694756 | 0.055313 |
| AFDN | afadin, adherens junction formation factor | 0.0549743 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0492562 |
| HLA-C | major histocompatibility complex, class I, C | 0.0490299 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0449967 |
| VCL | vinculin | 0.0443155 |
| SMAD3 | SMAD family member 3 | 0.0438476 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0432559 |
| SQSTM1 | sequestosome 1 | 0.0425273 |
| RUNX1 | runt-related transcription factor 1 | 0.0414526 |
| MYO5B | myosin VB | 0.0392249 |
| ARRDC3 | arrestin domain containing 3 | 0.0381257 |
| KIAA1671 | KIAA1671 | 0.0367807 |
| ANO6 | anoctamin 6 | 0.0360642 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0354776 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0338321 |
| LAMC2 | laminin, gamma 2 | 0.0321396 |
| FNIP1 | folliculin interacting protein 1 | 0.0313619 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313265 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0300614 |
| RACK1 | receptor for activated C kinase 1 | 0.0297773 |
| FLNB | filamin B, beta | 0.0294258 |
| FLNA | filamin A, alpha | 0.0289063 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0282833 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0272562 |
| HLA-B | major histocompatibility complex, class I, B | 0.0271656 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0269877 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.026839 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0266851 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0266333 |
| MCL1 | myeloid cell leukemia 1 | 0.0266115 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0260641 |
| EMP1 | epithelial membrane protein 1 | 0.0260584 |
| IRF6 | interferon regulatory factor 6 | 0.0259036 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0249774 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0247754 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0246518 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0239761 |
| RPL35A | ribosomal protein L35a | 0.0238178 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0237195 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0233761 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0233224 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0233156 |
| RPS3 | ribosomal protein S3 | 0.0232457 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0231209 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0230514 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0229822 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0229448 |
| FRMD6 | FERM domain containing 6 | 0.0226044 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.022195 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0216328 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0214299 |
| TUFT1 | tuftelin 1 | 0.0211907 |
| FMNL2 | formin-like 2 | 0.0209374 |
| SEPTIN9 | septin 9 | 0.0208814 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0206276 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0204741 |
| YEATS2 | YEATS domain containing 2 | 0.020272 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.020245 |
| RPL13A | ribosomal protein L13a | 0.0200931 |
| RPL3 | ribosomal protein L3 | 0.0197816 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0197273 |
| EGR1 | early growth response 1 | 0.019558 |
| YTHDC1 | YTH domain containing 1 | 0.0190059 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0183581 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0182119 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0180813 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0180543 |
| DTNA | dystrobrevin, alpha | 0.0180487 |
| CEP250 | centrosomal protein 250kDa | 0.018045 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0178724 |
| SCFD1 | sec1 family domain containing 1 | 0.0177498 |
| ANO10 | anoctamin 10 | 0.0176626 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0171948 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0171694 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0171389 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.016844 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0168311 |
| G0S2 | G0/G1 switch 2 | 0.0166214 |
| SP3 | Sp3 transcription factor | 0.0165323 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0164801 |
| DUSP10 | dual specificity phosphatase 10 | 0.0164493 |
| LRRC23 | leucine rich repeat containing 23 | 0.0163666 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0162416 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0162274 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0159963 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.015971 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0158959 |
| ANKRD10 | ankyrin repeat domain 10 | 0.015769 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0156632 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0156403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.348233 |
| PTMA | prothymosin, alpha | -0.15469 |
| TMSB10 | thymosin beta 10 | -0.145728 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.108206 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.106586 |
| KRT19 | keratin 19, type I | -0.102997 |
| RPS6 | ribosomal protein S6 | -0.0995589 |
| LMO7 | LIM domain 7 | -0.0979827 |
| MUC4 | mucin 4, cell surface associated | -0.0723689 |
| B2M | beta-2-microglobulin | -0.0715012 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0704629 |
| LAMA4 | laminin, alpha 4 | -0.0692737 |
| HMGA1 | high mobility group AT-hook 1 | -0.0650439 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0649158 |
| YBX3 | Y box binding protein 3 | -0.0646784 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0640518 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0615386 |
| MYO1E | myosin IE | -0.0606864 |
| MT2A | metallothionein 2A | -0.0594759 |
| POTEF | POTE ankyrin domain family, member F | -0.0576874 |
| OSMR | oncostatin M receptor | -0.0566948 |
| S100A6 | S100 calcium binding protein A6 | -0.0553878 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0549274 |
| OXSR1 | oxidative stress responsive 1 | -0.053906 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0534516 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0519402 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0518616 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0514701 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0514317 |
| RPL8 | ribosomal protein L8 | -0.0512473 |
| WWC1 | WW and C2 domain containing 1 | -0.0502276 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0500891 |
| SVIL | supervillin | -0.050056 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0498595 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0484496 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0483163 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.047668 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0475771 |
| RPS19 | ribosomal protein S19 | -0.047536 |
| TMSB4X | thymosin beta 4, X-linked | -0.0466752 |
| EFNA5 | ephrin-A5 | -0.0462111 |
| TXNIP | thioredoxin interacting protein | -0.045808 |
| S100A10 | S100 calcium binding protein A10 | -0.0456617 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0455233 |
| CD2AP | CD2-associated protein | -0.0442103 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0424726 |
| RPS15 | ribosomal protein S15 | -0.0423674 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.041784 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0417603 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0416402 |
| JMJD1C | jumonji domain containing 1C | -0.0412637 |
| FN1 | fibronectin 1 | -0.0410731 |
| RPL28 | ribosomal protein L28 | -0.0407408 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.040448 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0400472 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0394632 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0394055 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0382458 |
| ASTN2 | astrotactin 2 | -0.0375255 |
| MX2 | MX dynamin-like GTPase 2 | -0.036977 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0368164 |
| EZR | ezrin | -0.0362742 |
| HLA-A | major histocompatibility complex, class I, A | -0.036175 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360796 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0357059 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0356024 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0355401 |
| C3 | complement component 3 | -0.0347161 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0346756 |
| TPM4 | tropomyosin 4 | -0.034638 |
| PKM | pyruvate kinase, muscle | -0.0340647 |
| RPL23 | ribosomal protein L23 | -0.0336598 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0333429 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0328266 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0326222 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0325286 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0323267 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0319985 |
| S100A9 | S100 calcium binding protein A9 | -0.0317148 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0317128 |
| S100A11 | S100 calcium binding protein A11 | -0.0314496 |
| DSG2 | desmoglein 2 | -0.0312578 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0312014 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0310549 |
| H1-0 | H1.0 linker histone | -0.0310295 |
| TMEM123 | transmembrane protein 123 | -0.0310017 |
| RPS14 | ribosomal protein S14 | -0.0309912 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0308708 |
| FTL | ferritin, light polypeptide | -0.0306799 |
| TPI1 | triosephosphate isomerase 1 | -0.030357 |
| CBX3 | chromobox homolog 3 | -0.0303 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0302169 |
| NRP1 | neuropilin 1 | -0.0300842 |
| RPS21 | ribosomal protein S21 | -0.0298058 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0296107 |
| MX1 | MX dynamin-like GTPase 1 | -0.0294812 |
| RNF213 | ring finger protein 213 | -0.0294596 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0292622 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0289223 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0288251 |
