| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.374493 |
| NDRG1 | N-myc downstream regulated 1 | 0.169671 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.123323 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0787345 |
| PLEC | plectin | 0.0687392 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0671349 |
| VEGFA | vascular endothelial growth factor A | 0.0632721 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0624149 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0590554 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0555097 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0540119 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0527072 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.052302 |
| POTEF | POTE ankyrin domain family, member F | 0.0520017 |
| CD109 | CD109 molecule | 0.046986 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0465512 |
| CALR | calreticulin | 0.0459874 |
| MSN | moesin | 0.0456052 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0451587 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0449619 |
| FLNA | filamin A, alpha | 0.0449278 |
| PKM | pyruvate kinase, muscle | 0.0422451 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0397878 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.038849 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0380806 |
| CTSB | cathepsin B | 0.0376608 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0369358 |
| ENO1 | enolase 1, (alpha) | 0.0359526 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0352337 |
| LMNA | lamin A/C | 0.0350665 |
| GOLGA4 | golgin A4 | 0.0344774 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0342347 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0341163 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0341027 |
| FAM162A | family with sequence similarity 162, member A | 0.0338935 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0333336 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0324166 |
| COL5A1 | collagen, type V, alpha 1 | 0.0317737 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0303413 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0300915 |
| INSIG2 | insulin induced gene 2 | 0.0300521 |
| PCBP2 | poly(rC) binding protein 2 | 0.0295455 |
| TPM1 | tropomyosin 1 (alpha) | 0.0290603 |
| FAM13A | family with sequence similarity 13, member A | 0.028979 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0288803 |
| TPM3 | tropomyosin 3 | 0.0288347 |
| CEP250 | centrosomal protein 250kDa | 0.0281255 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0269524 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0269488 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0267826 |
| RPL3 | ribosomal protein L3 | 0.0265132 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0262707 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0262583 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0252924 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0250505 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0245761 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0245597 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0242253 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0241093 |
| C1D | C1D nuclear receptor corepressor | 0.0237419 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0233341 |
| RYBP | RING1 and YY1 binding protein | 0.0230552 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0228835 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.022848 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0228217 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0226372 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0224978 |
| ACTN1 | actinin, alpha 1 | 0.0224334 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0223934 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0221589 |
| MCL1 | myeloid cell leukemia 1 | 0.0220321 |
| YEATS2 | YEATS domain containing 2 | 0.0220067 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0218497 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0216523 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0215687 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0215323 |
| ARRDC3 | arrestin domain containing 3 | 0.0215167 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0212162 |
| HDLBP | high density lipoprotein binding protein | 0.0210838 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.02098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0209756 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0208606 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0206627 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0204849 |
| ADM | adrenomedullin | 0.020474 |
| MYOF | myoferlin | 0.0204604 |
| MTSS1 | metastasis suppressor 1 | 0.0204594 |
| NCKAP1 | NCK-associated protein 1 | 0.0203621 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0203137 |
| MMP2 | matrix metallopeptidase 2 | 0.0202891 |
| TGM2 | transglutaminase 2 | 0.0202088 |
| WDR45B | WD repeat domain 45B | 0.0202041 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0201873 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0200812 |
| NUP58 | nucleoporin 58 | 0.0200372 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0199182 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0196731 |
| MATR3 | matrin 3 | 0.0194473 |
| SURF4 | surfeit 4 | 0.0194105 |
| FLNB | filamin B, beta | 0.0193811 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197453 |
| VIM | vimentin | -0.160789 |
| FRMD4A | FERM domain containing 4A | -0.109406 |
| CD44 | CD44 molecule (Indian blood group) | -0.0920216 |
| MT2A | metallothionein 2A | -0.0721409 |
| NRP1 | neuropilin 1 | -0.0646224 |
| STC1 | stanniocalcin 1 | -0.0566271 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.055411 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0526873 |
| COL1A1 | collagen, type I, alpha 1 | -0.0509131 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0495771 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0495553 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0480555 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0471466 |
| HLA-B | major histocompatibility complex, class I, B | -0.0465707 |
| GLIS3 | GLIS family zinc finger 3 | -0.0459593 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0454388 |
| TMSB10 | thymosin beta 10 | -0.0449583 |
| NF1 | neurofibromin 1 | -0.0444978 |
| TCF12 | transcription factor 12 | -0.0421255 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0420168 |
| VCL | vinculin | -0.0412021 |
| SVIL | supervillin | -0.0405777 |
| COL1A2 | collagen, type I, alpha 2 | -0.040298 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0400598 |
| IER3 | immediate early response 3 | -0.0393703 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0387073 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0385433 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0381521 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0379862 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0375897 |
| HMGA2 | high mobility group AT-hook 2 | -0.0373981 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.036636 |
| ASPH | aspartate beta-hydroxylase | -0.0361818 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0357435 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0348907 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0347485 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0345503 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0328234 |
| SETD5 | SET domain containing 5 | -0.0326262 |
| USP34 | ubiquitin specific peptidase 34 | -0.0326049 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0317463 |
| PMP22 | peripheral myelin protein 22 | -0.0315587 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0314261 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.028881 |
| RAB10 | RAB10, member RAS oncogene family | -0.0287508 |
| NAV1 | neuron navigator 1 | -0.0285887 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0285018 |
| PTMA | prothymosin, alpha | -0.0283199 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0275874 |
| MAP4 | microtubule-associated protein 4 | -0.0274724 |
| PHF14 | PHD finger protein 14 | -0.0273785 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0273704 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0273172 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0272039 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0271782 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.027004 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0268955 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0267201 |
| FHIT | fragile histidine triad | -0.0265957 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0265024 |
| HPCAL1 | hippocalcin-like 1 | -0.0264305 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0263737 |
| PCBP3 | poly(rC) binding protein 3 | -0.0257866 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0254477 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0253924 |
| H1-0 | H1.0 linker histone | -0.025352 |
| IL1B | interleukin 1, beta | -0.0252702 |
| RAB7A | RAB7A, member RAS oncogene family | -0.025154 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0250535 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0250312 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0248556 |
| OSMR | oncostatin M receptor | -0.0246287 |
| XAF1 | XIAP associated factor 1 | -0.0245807 |
| VMP1 | vacuole membrane protein 1 | -0.0245475 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0245322 |
| AHNAK | AHNAK nucleoprotein | -0.0245134 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0242664 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0242603 |
| ANKRD17 | ankyrin repeat domain 17 | -0.024249 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0241229 |
| BPTF | bromodomain PHD finger transcription factor | -0.0239308 |
| SP100 | SP100 nuclear antigen | -0.0236159 |
| DIAPH3 | diaphanous-related formin 3 | -0.0236093 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0234509 |
| SBF2 | SET binding factor 2 | -0.0233798 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0233394 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0232345 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0227359 |
| PGK1 | phosphoglycerate kinase 1 | -0.0225446 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0222994 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0221726 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0221498 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0221016 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.022041 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0220365 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0220338 |
| S100A10 | S100 calcium binding protein A10 | -0.0219611 |
| ITGA1 | integrin, alpha 1 | -0.0219571 |
| FTL | ferritin, light polypeptide | -0.0219527 |
