| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.231418 |
| VGF | VGF nerve growth factor inducible | 0.13941 |
| PDE10A | phosphodiesterase 10A | 0.132291 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0862795 |
| CHGB | chromogranin B | 0.077617 |
| FAM13A | family with sequence similarity 13, member A | 0.0717584 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0657375 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0656448 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0621304 |
| MAP1B | microtubule-associated protein 1B | 0.0577118 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0576652 |
| NRG1 | neuregulin 1 | 0.0574659 |
| STC1 | stanniocalcin 1 | 0.0550267 |
| PAEP | progestagen-associated endometrial protein | 0.0549131 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0536988 |
| HMGB3 | high mobility group box 3 | 0.0503026 |
| CPE | carboxypeptidase E | 0.0477337 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0476606 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0464827 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0460553 |
| MCL1 | myeloid cell leukemia 1 | 0.0459966 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0455835 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0448169 |
| RTN4 | reticulon 4 | 0.0433775 |
| NAV2 | neuron navigator 2 | 0.0409319 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0408071 |
| ENO1 | enolase 1, (alpha) | 0.0404501 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0402989 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0402051 |
| TPM3 | tropomyosin 3 | 0.0387262 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0378514 |
| PCBP2 | poly(rC) binding protein 2 | 0.0378041 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.037634 |
| NUP58 | nucleoporin 58 | 0.0375574 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0375022 |
| WDR45B | WD repeat domain 45B | 0.0374341 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0367598 |
| FAT1 | FAT atypical cadherin 1 | 0.0364837 |
| SCG2 | secretogranin II | 0.0357675 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0352849 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0352574 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0348638 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0341563 |
| GSE1 | Gse1 coiled-coil protein | 0.0337987 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0334821 |
| TPD52 | tumor protein D52 | 0.0328428 |
| ACTG1 | actin gamma 1 | 0.0326258 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0324928 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324689 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0321859 |
| POTEF | POTE ankyrin domain family, member F | 0.0320918 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0319493 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0317771 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0316422 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0315312 |
| MSN | moesin | 0.0314703 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0313734 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0313094 |
| TXNRD1 | thioredoxin reductase 1 | 0.0312388 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0307124 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0303038 |
| CELF4 | CUGBP, Elav-like family member 4 | 0.0300765 |
| TMEM255B | transmembrane protein 255B | 0.0297986 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0296795 |
| VEGFA | vascular endothelial growth factor A | 0.0294391 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0292284 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0291567 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0289678 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0289133 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0283381 |
| NBAS | neuroblastoma amplified sequence | 0.0282839 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.027914 |
| SCARB2 | scavenger receptor class B, member 2 | 0.027609 |
| RPL3 | ribosomal protein L3 | 0.0272279 |
| NCKAP5 | NCK-associated protein 5 | 0.0270669 |
| AHR | aryl hydrocarbon receptor | 0.0268777 |
| TSPYL2 | TSPY-like 2 | 0.0265531 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0256471 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0254496 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.024896 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0248331 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.0236776 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0236062 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0236005 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0234713 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0234681 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0232666 |
| UBC | ubiquitin C | 0.0230716 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0229431 |
| TMSB4X | thymosin beta 4, X-linked | 0.0228635 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0228147 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0227116 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.022583 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0225824 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0225558 |
| RORA | RAR-related orphan receptor A | 0.0225133 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0223754 |
| SVIL | supervillin | 0.0222762 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0222063 |
| KMT5B | lysine methyltransferase 5B | 0.022131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.212913 |
| FTL | ferritin, light polypeptide | -0.0782694 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0778669 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0664395 |
| RPL37A | ribosomal protein L37a | -0.064609 |
| TENM1 | teneurin transmembrane protein 1 | -0.0623989 |
| RPL26 | ribosomal protein L26 | -0.050339 |
| RPS21 | ribosomal protein S21 | -0.0485246 |
| RPS8 | ribosomal protein S8 | -0.0484955 |
| RPL23 | ribosomal protein L23 | -0.0457445 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0448463 |
| MT2A | metallothionein 2A | -0.0441531 |
| RPS6 | ribosomal protein S6 | -0.0420511 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0411308 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0386766 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0383435 |
| CENPF | centromere protein F, 350/400kDa | -0.0383191 |
| RPL12 | ribosomal protein L12 | -0.0382851 |
| RPS19 | ribosomal protein S19 | -0.0379736 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0370171 |
| GOLGB1 | golgin B1 | -0.0368995 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0367524 |
| RPS3 | ribosomal protein S3 | -0.0367428 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0354607 |
| PEG10 | paternally expressed 10 | -0.0348741 |
| RPL19 | ribosomal protein L19 | -0.0347432 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0343284 |
| FNDC3A | fibronectin type III domain containing 3A | -0.033542 |
| SYT1 | synaptotagmin I | -0.0330899 |
| TMSB10 | thymosin beta 10 | -0.0330425 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0325211 |
| RPS16 | ribosomal protein S16 | -0.0324165 |
| GLCCI1 | glucocorticoid induced 1 | -0.0313466 |
| KNL1 | kinetochore scaffold 1 | -0.0309922 |
| GPC5 | glypican 5 | -0.0304683 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0304048 |
| MKI67 | marker of proliferation Ki-67 | -0.0299336 |
| RPL31 | ribosomal protein L31 | -0.0298296 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0296228 |
| RPL36 | ribosomal protein L36 | -0.0293926 |
| RPL30 | ribosomal protein L30 | -0.0293723 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0292981 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.029283 |
| RPS27A | ribosomal protein S27a | -0.029202 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0289425 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0289412 |
| TNRC6C | trinucleotide repeat containing 6C | -0.0285582 |
| HMGB1 | high mobility group box 1 | -0.0285145 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284951 |
| RPL34 | ribosomal protein L34 | -0.0284345 |
| FOXC1 | forkhead box C1 | -0.028245 |
| SNTG1 | syntrophin, gamma 1 | -0.0282366 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0281965 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.0281616 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.027777 |
| H1-0 | H1.0 linker histone | -0.027677 |
| INHBA | inhibin, beta A | -0.0275784 |
| RPL35 | ribosomal protein L35 | -0.0271413 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0270853 |
| RPL35A | ribosomal protein L35a | -0.0266792 |
| RPL37 | ribosomal protein L37 | -0.0266466 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0265688 |
| RPL38 | ribosomal protein L38 | -0.0261305 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0260268 |
| KIAA1958 | KIAA1958 | -0.025893 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | -0.0257902 |
| RPS12 | ribosomal protein S12 | -0.0255563 |
| RACK1 | receptor for activated C kinase 1 | -0.0254084 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0253161 |
| PBK | PDZ binding kinase | -0.0252163 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0251998 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0250908 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0248357 |
| RPS27 | ribosomal protein S27 | -0.0245552 |
| HMGB2 | high mobility group box 2 | -0.0243708 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0243259 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0241229 |
| BPTF | bromodomain PHD finger transcription factor | -0.0238248 |
| RPL5 | ribosomal protein L5 | -0.0237278 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0235912 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0235019 |
| ZNF804A | zinc finger protein 804A | -0.0234851 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0230076 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0227755 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0227283 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.022637 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | -0.0225705 |
| SGO2 | shugoshin 2 | -0.0225659 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0218085 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0217933 |
| RPL36AL | ribosomal protein L36a-like | -0.0217476 |
| CDK13 | cyclin-dependent kinase 13 | -0.0215548 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0213947 |
| RPL11 | ribosomal protein L11 | -0.0209 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0207464 |
| PCM1 | pericentriolar material 1 | -0.0206437 |
| KNTC1 | kinetochore associated 1 | -0.0205776 |
| CANX | calnexin | -0.0204539 |
| RPS29 | ribosomal protein S29 | -0.0203973 |
| RPS25 | ribosomal protein S25 | -0.0203587 |
