| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.19667 |
| FNDC3B | fibronectin type III domain containing 3B | 0.067774 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0606126 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0494546 |
| NDRG1 | N-myc downstream regulated 1 | 0.0474453 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0448286 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0434741 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0419689 |
| FLNA | filamin A, alpha | 0.0407735 |
| PRELID2 | PRELI domain containing 2 | 0.0400584 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0400293 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0384145 |
| PLEC | plectin | 0.0377257 |
| NAV2 | neuron navigator 2 | 0.0365294 |
| MSI2 | musashi RNA-binding protein 2 | 0.0364967 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0324267 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0317265 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0310368 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0308098 |
| SMAD3 | SMAD family member 3 | 0.0296778 |
| KAZN | kazrin, periplakin interacting protein | 0.029424 |
| RPL3 | ribosomal protein L3 | 0.0267901 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0248451 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.023727 |
| CABIN1 | calcineurin binding protein 1 | 0.0231637 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.022931 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.022796 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0227523 |
| AFDN | afadin, adherens junction formation factor | 0.0226069 |
| FMNL2 | formin-like 2 | 0.0222895 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0220384 |
| SEPTIN9 | septin 9 | 0.0218483 |
| YEATS2 | YEATS domain containing 2 | 0.0215913 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0204311 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.0200354 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0198611 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0198593 |
| MMP12 | matrix metallopeptidase 12 | 0.0198029 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0193809 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0191943 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0187972 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0187166 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0184243 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0178528 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0175961 |
| CD109 | CD109 molecule | 0.0174823 |
| HLA-C | major histocompatibility complex, class I, C | 0.0173252 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.017259 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0172475 |
| DST | dystonin | 0.0167996 |
| NGLY1 | N-glycanase 1 | 0.0164549 |
| FAM219A | family with sequence similarity 219, member A | 0.0163538 |
| TNNC1 | troponin C type 1 (slow) | 0.0160765 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0160716 |
| FLNB | filamin B, beta | 0.0160458 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0158931 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.015886 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0155925 |
| ARRDC3 | arrestin domain containing 3 | 0.0155011 |
| DENND1A | DENN/MADD domain containing 1A | 0.0154239 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0152255 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.0150367 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0149717 |
| FHIT | fragile histidine triad | 0.0147892 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0146469 |
| CA8 | carbonic anhydrase VIII | 0.0144159 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0139844 |
| TRIM33 | tripartite motif containing 33 | 0.0139746 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0137908 |
| HPCAL1 | hippocalcin-like 1 | 0.0137455 |
| TUBB | tubulin, beta class I | 0.01365 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0135743 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0134828 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0134583 |
| HMG20B | high mobility group 20B | 0.0133049 |
| ANGPTL4 | angiopoietin-like 4 | 0.0132553 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0132114 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.013178 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0131584 |
| CDH13 | cadherin 13 | 0.0130685 |
| FRMD4A | FERM domain containing 4A | 0.0128859 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0128783 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.012742 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0126824 |
| CEP250 | centrosomal protein 250kDa | 0.0126511 |
| ITGB5 | integrin, beta 5 | 0.0125701 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0124438 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.012223 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0121458 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.0120263 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0119271 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0116862 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0116553 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0113432 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.0113277 |
| TMEM51 | transmembrane protein 51 | 0.0112941 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.0112319 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0112209 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0108217 |
| HJURP | Holliday junction recognition protein | 0.0107294 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.290649 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229417 |
| UBC | ubiquitin C | -0.105989 |
| PTMA | prothymosin, alpha | -0.0864858 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0839196 |
| ENO1 | enolase 1, (alpha) | -0.0798971 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0714463 |
| TMSB10 | thymosin beta 10 | -0.063614 |
| PKM | pyruvate kinase, muscle | -0.06325 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0629358 |
| RPS27A | ribosomal protein S27a | -0.0567966 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527381 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0493044 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.049048 |
| CCND1 | cyclin D1 | -0.0478937 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0477089 |
| SQSTM1 | sequestosome 1 | -0.0474485 |
| FTL | ferritin, light polypeptide | -0.0468294 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0430344 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0427893 |
| POTEF | POTE ankyrin domain family, member F | -0.0419057 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0411407 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0392481 |
| PCBP2 | poly(rC) binding protein 2 | -0.0388141 |
| RPS8 | ribosomal protein S8 | -0.0383226 |
| RPS6 | ribosomal protein S6 | -0.0383193 |
| NLGN1 | neuroligin 1 | -0.0382666 |
| MT2A | metallothionein 2A | -0.037795 |
| B2M | beta-2-microglobulin | -0.037774 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.037646 |
| RPL23 | ribosomal protein L23 | -0.0376303 |
| RPL36A | ribosomal protein L36a | -0.0365592 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0360059 |
| RPLP2 | ribosomal protein, large, P2 | -0.035712 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0349469 |
| RPS23 | ribosomal protein S23 | -0.034829 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0340067 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0336797 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0334624 |
| VMP1 | vacuole membrane protein 1 | -0.0333209 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0331165 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328747 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0328672 |
| CD44 | CD44 molecule (Indian blood group) | -0.0325502 |
| TXNRD1 | thioredoxin reductase 1 | -0.0324966 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0319994 |
| RPS24 | ribosomal protein S24 | -0.0316958 |
| HLA-B | major histocompatibility complex, class I, B | -0.0314614 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0313257 |
| SEPTIN7 | septin 7 | -0.0308866 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0304073 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0303848 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0300318 |
| EMP1 | epithelial membrane protein 1 | -0.0299506 |
| RPLP1 | ribosomal protein, large, P1 | -0.0292879 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0292528 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0284671 |
| MAP4 | microtubule-associated protein 4 | -0.0284597 |
| FUS | FUS RNA binding protein | -0.0272998 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0272468 |
| APOD | apolipoprotein D | -0.0266921 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0262529 |
| RPL31 | ribosomal protein L31 | -0.0262133 |
| SP100 | SP100 nuclear antigen | -0.0260626 |
| RPS15 | ribosomal protein S15 | -0.0258498 |
| BPTF | bromodomain PHD finger transcription factor | -0.0255585 |
| RPL15 | ribosomal protein L15 | -0.0250733 |
| ASPH | aspartate beta-hydroxylase | -0.0250465 |
| RPS13 | ribosomal protein S13 | -0.0249436 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0248466 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0246745 |
| RPS29 | ribosomal protein S29 | -0.0246268 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0245193 |
| H3-3B | H3.3 histone B | -0.0244075 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0241648 |
| RPS5 | ribosomal protein S5 | -0.0239232 |
| S100A10 | S100 calcium binding protein A10 | -0.0236599 |
| RPS14 | ribosomal protein S14 | -0.0235444 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0234223 |
| RPL5 | ribosomal protein L5 | -0.0234178 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0233404 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0231116 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0226931 |
| HMGA1 | high mobility group AT-hook 1 | -0.0225763 |
| RPL19 | ribosomal protein L19 | -0.0225642 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0224828 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0223201 |
| TPM4 | tropomyosin 4 | -0.0220772 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0220256 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0219724 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0219455 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0218261 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0215862 |
| RPL32 | ribosomal protein L32 | -0.0215272 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0214216 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0214012 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0212201 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0211975 |
| S100A9 | S100 calcium binding protein A9 | -0.0211663 |
| AHNAK | AHNAK nucleoprotein | -0.0211093 |
