| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.130103 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.10599 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.10003 |
| FN1 | fibronectin 1 | 0.0833415 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0728892 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0679432 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.067185 |
| ARRDC3 | arrestin domain containing 3 | 0.0562929 |
| PTK2 | protein tyrosine kinase 2 | 0.053566 |
| CD44 | CD44 molecule (Indian blood group) | 0.0529528 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0514874 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0491488 |
| NAV2 | neuron navigator 2 | 0.0462577 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0454102 |
| FAM13A | family with sequence similarity 13, member A | 0.0443659 |
| WTAP | Wilms tumor 1 associated protein | 0.0441166 |
| CCDC88A | coiled-coil domain containing 88A | 0.0432312 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0427302 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0424864 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0423911 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0407054 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0395142 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0393485 |
| FMNL2 | formin-like 2 | 0.0389397 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0380423 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.035194 |
| MRTFA | myocardin related transcription factor A | 0.0344882 |
| RPL34 | ribosomal protein L34 | 0.0339105 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0330566 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.032584 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0325183 |
| PCBP2 | poly(rC) binding protein 2 | 0.0319726 |
| OXR1 | oxidation resistance 1 | 0.0311158 |
| RNF145 | ring finger protein 145 | 0.0306062 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0304829 |
| RTN4 | reticulon 4 | 0.0302001 |
| CADM1 | cell adhesion molecule 1 | 0.0296521 |
| NRG1 | neuregulin 1 | 0.0296075 |
| GPC6 | glypican 6 | 0.0292416 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0290893 |
| MATR3 | matrin 3 | 0.0289906 |
| RPL11 | ribosomal protein L11 | 0.0288263 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0285826 |
| ANLN | anillin, actin binding protein | 0.0282151 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0271533 |
| RPLP1 | ribosomal protein, large, P1 | 0.0267514 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0262442 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0261752 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0260443 |
| SETBP1 | SET binding protein 1 | 0.0258538 |
| AUTS2 | autism susceptibility candidate 2 | 0.0255629 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253499 |
| ZNF292 | zinc finger protein 292 | 0.0253496 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0252971 |
| NDRG1 | N-myc downstream regulated 1 | 0.0252942 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0250894 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0248736 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0248118 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0245172 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0244932 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0243994 |
| FOXJ3 | forkhead box J3 | 0.0243105 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0241337 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0238714 |
| CEP43 | centrosomal protein 43 | 0.0237949 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0236804 |
| SMAD3 | SMAD family member 3 | 0.0232472 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.023028 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0229429 |
| LOXL2 | lysyl oxidase-like 2 | 0.022572 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0221645 |
| RACK1 | receptor for activated C kinase 1 | 0.0220444 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0220041 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0219591 |
| PRKD3 | protein kinase D3 | 0.0217727 |
| TENM3 | teneurin transmembrane protein 3 | 0.0217303 |
| ECE1 | endothelin converting enzyme 1 | 0.0217264 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0217248 |
| DIAPH1 | diaphanous-related formin 1 | 0.0216971 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.021516 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0214912 |
| GPATCH8 | G patch domain containing 8 | 0.0214867 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0214515 |
| RASA3 | RAS p21 protein activator 3 | 0.0214212 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0213852 |
| SREK1IP1 | SREK1-interacting protein 1 | 0.0213799 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0212821 |
| TKT | transketolase | 0.0210667 |
| UBE3A | ubiquitin protein ligase E3A | 0.0210661 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0209364 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.020897 |
| ANXA2 | annexin A2 | 0.0208329 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0208017 |
| CHMP4B | charged multivesicular body protein 4B | 0.0207628 |
| CDC27 | cell division cycle 27 | 0.0207237 |
| PRPF39 | pre-mRNA processing factor 39 | 0.0206831 |
| USP12 | ubiquitin specific peptidase 12 | 0.0206782 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0204588 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0202703 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0202581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.131866 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0845681 |
| MAP1B | microtubule-associated protein 1B | -0.083578 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0784825 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0772075 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0746838 |
| B2M | beta-2-microglobulin | -0.0633656 |
| HLA-B | major histocompatibility complex, class I, B | -0.0598057 |
| EGFR | epidermal growth factor receptor | -0.0596861 |
| TMSB10 | thymosin beta 10 | -0.0593305 |
| TMEM165 | transmembrane protein 165 | -0.0592707 |
| GOLGA4 | golgin A4 | -0.058007 |
| CALU | calumenin | -0.0556263 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0529394 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.052728 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.052143 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.052004 |
| COL1A2 | collagen, type I, alpha 2 | -0.0511636 |
| HLA-C | major histocompatibility complex, class I, C | -0.0496445 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0494522 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0440914 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0437369 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0436454 |
| SEC24D | SEC24 family member D | -0.042975 |
| MYADM | myeloid-associated differentiation marker | -0.0428165 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0417618 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0412963 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0409597 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0405994 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0400344 |
| MT2A | metallothionein 2A | -0.0394105 |
| CANX | calnexin | -0.0380038 |
| COL5A2 | collagen, type V, alpha 2 | -0.0369163 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0365485 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0356668 |
| VIM | vimentin | -0.0356333 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0352295 |
| STC1 | stanniocalcin 1 | -0.0345543 |
| SDC4 | syndecan 4 | -0.0342362 |
| COL1A1 | collagen, type I, alpha 1 | -0.0338671 |
| VCL | vinculin | -0.0334541 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0333241 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0326327 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0320008 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0313664 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0296519 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0296461 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0293995 |
| IL6 | interleukin 6 | -0.0293376 |
| RND3 | Rho family GTPase 3 | -0.0292332 |
| CDK13 | cyclin-dependent kinase 13 | -0.0287364 |
| SPAG9 | sperm associated antigen 9 | -0.0286463 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0285898 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0283852 |
| COPA | coatomer protein complex, subunit alpha | -0.0282058 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0280856 |
| LDHA | lactate dehydrogenase A | -0.0280308 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0275954 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0275496 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0274769 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0271089 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0270855 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0270658 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0270045 |
| USP34 | ubiquitin specific peptidase 34 | -0.0269414 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0268016 |
| TAGLN2 | transgelin 2 | -0.0266966 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0264753 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0263757 |
| PRKCA | protein kinase C, alpha | -0.0263426 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0262623 |
| PTGES2 | prostaglandin E synthase 2 | -0.0261968 |
| KIF1B | kinesin family member 1B | -0.0255883 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0255221 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0253934 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0253823 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0251257 |
| KAZN | kazrin, periplakin interacting protein | -0.0249687 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0248366 |
| MTDH | metadherin | -0.0247745 |
| SEC24A | SEC24 family member A | -0.0247362 |
| HIP1 | huntingtin interacting protein 1 | -0.0247264 |
| ASPH | aspartate beta-hydroxylase | -0.0245548 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.024004 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0238022 |
| CMIP | c-Maf inducing protein | -0.0236862 |
| LMNA | lamin A/C | -0.0235739 |
| LOX | lysyl oxidase | -0.0234518 |
| PHF20 | PHD finger protein 20 | -0.0234465 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0234236 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0234198 |
| MYO9A | myosin IXA | -0.0234174 |
| TMEM41B | transmembrane protein 41B | -0.023409 |
| RAB31 | RAB31, member RAS oncogene family | -0.0231925 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0231447 |
| KYNU | kynureninase | -0.0231313 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | -0.0228722 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0228604 |
| TNS3 | tensin 3 | -0.0228385 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0228169 |
