| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.145993 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.12052 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.115421 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.103427 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0947165 |
| SMAD3 | SMAD family member 3 | 0.0786118 |
| GLIS3 | GLIS family zinc finger 3 | 0.0736155 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0619885 |
| AHR | aryl hydrocarbon receptor | 0.0605976 |
| ITGA1 | integrin, alpha 1 | 0.0589891 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0567109 |
| OSMR | oncostatin M receptor | 0.0525638 |
| PRELID2 | PRELI domain containing 2 | 0.0522497 |
| PTK2 | protein tyrosine kinase 2 | 0.0490311 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0485348 |
| SMOX | spermine oxidase | 0.0483601 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0472165 |
| CENPF | centromere protein F, 350/400kDa | 0.0469324 |
| FN1 | fibronectin 1 | 0.0460645 |
| NDRG1 | N-myc downstream regulated 1 | 0.0453526 |
| CLTC | clathrin, heavy chain (Hc) | 0.0406496 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0405808 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0392833 |
| SUCO | SUN domain containing ossification factor | 0.0392797 |
| FAM13A | family with sequence similarity 13, member A | 0.0388675 |
| FAT1 | FAT atypical cadherin 1 | 0.0378574 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0375098 |
| PRRC2C | proline-rich coiled-coil 2C | 0.037198 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0367243 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0364595 |
| ETV6 | ets variant 6 | 0.0356865 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.03438 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0339143 |
| HDLBP | high density lipoprotein binding protein | 0.0339072 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0336947 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0335313 |
| ANO6 | anoctamin 6 | 0.032787 |
| WDR26 | WD repeat domain 26 | 0.0326793 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.032551 |
| CD44 | CD44 molecule (Indian blood group) | 0.0322184 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0313754 |
| COG5 | component of oligomeric golgi complex 5 | 0.0306757 |
| YEATS2 | YEATS domain containing 2 | 0.0306233 |
| OGA | O-GlcNAcase | 0.0306203 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0302957 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0302696 |
| IL6ST | interleukin 6 signal transducer | 0.0300388 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.029995 |
| RBM39 | RNA binding motif protein 39 | 0.0294502 |
| SMYD3 | SET and MYND domain containing 3 | 0.029266 |
| MKI67 | marker of proliferation Ki-67 | 0.0292212 |
| NAV2 | neuron navigator 2 | 0.0291514 |
| TPR | translocated promoter region, nuclear basket protein | 0.028751 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0277336 |
| CDC73 | cell division cycle 73 | 0.0276366 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0275252 |
| RUNX2 | runt-related transcription factor 2 | 0.0272704 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0270159 |
| TMEM156 | transmembrane protein 156 | 0.0265241 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0263358 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0262623 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.025838 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0255436 |
| DST | dystonin | 0.0251703 |
| NBAS | neuroblastoma amplified sequence | 0.0250173 |
| FRY | furry homolog (Drosophila) | 0.0250056 |
| TLN1 | talin 1 | 0.024996 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0247273 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0244935 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0244803 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0243674 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0241406 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0241012 |
| CDCP1 | CUB domain containing protein 1 | 0.0240996 |
| SLTM | SAFB-like, transcription modulator | 0.024038 |
| AFDN | afadin, adherens junction formation factor | 0.0240175 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0240126 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0239946 |
| PELO | pelota homolog (Drosophila) | 0.0239083 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.023738 |
| HPCAL1 | hippocalcin-like 1 | 0.023647 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0235765 |
| CTBP2 | C-terminal binding protein 2 | 0.0235054 |
| ATXN1 | ataxin 1 | 0.0234846 |
| SEC24C | SEC24 family member C | 0.02343 |
| FOXO3 | forkhead box O3 | 0.023261 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.0230076 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0227878 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0226794 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.022645 |
| CD109 | CD109 molecule | 0.0226295 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0226271 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0225914 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0225376 |
| IDS | iduronate 2-sulfatase | 0.0224969 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0224862 |
| FLNA | filamin A, alpha | 0.0224592 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0224456 |
| WDR45B | WD repeat domain 45B | 0.0220786 |
| ACTN4 | actinin, alpha 4 | 0.0220368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.219731 |
| PTMA | prothymosin, alpha | -0.150169 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.128509 |
| MT2A | metallothionein 2A | -0.105039 |
| TMSB10 | thymosin beta 10 | -0.103155 |
| FTL | ferritin, light polypeptide | -0.101366 |
| NRG1 | neuregulin 1 | -0.0692116 |
| B2M | beta-2-microglobulin | -0.0662557 |
| VIM | vimentin | -0.0602928 |
| HLA-B | major histocompatibility complex, class I, B | -0.0571456 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527329 |
| RPL37A | ribosomal protein L37a | -0.0497937 |
| RPL35A | ribosomal protein L35a | -0.0475818 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0462792 |
| INTS6 | integrator complex subunit 6 | -0.04441 |
| RPS6 | ribosomal protein S6 | -0.0429796 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0420228 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0416969 |
| VCL | vinculin | -0.0405856 |
| RPL31 | ribosomal protein L31 | -0.0403731 |
| TXNIP | thioredoxin interacting protein | -0.039959 |
| RPL9 | ribosomal protein L9 | -0.0393153 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.038289 |
| RPS19 | ribosomal protein S19 | -0.0381438 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0362421 |
| ASPH | aspartate beta-hydroxylase | -0.0361818 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0356504 |
| RPS12 | ribosomal protein S12 | -0.0349267 |
| RPS8 | ribosomal protein S8 | -0.0347629 |
| RPL12 | ribosomal protein L12 | -0.0339874 |
| RPL19 | ribosomal protein L19 | -0.0339198 |
| RPS29 | ribosomal protein S29 | -0.033787 |
| S100A10 | S100 calcium binding protein A10 | -0.0327716 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0320703 |
| RPL23 | ribosomal protein L23 | -0.0315095 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0311293 |
| GNAS | GNAS complex locus | -0.0304973 |
| SQSTM1 | sequestosome 1 | -0.0302465 |
| RPS27A | ribosomal protein S27a | -0.0299648 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0299145 |
| RPS27 | ribosomal protein S27 | -0.029637 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0296083 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.029593 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0294652 |
| S100A6 | S100 calcium binding protein A6 | -0.0293754 |
| MAP1B | microtubule-associated protein 1B | -0.0293735 |
| ACTG1 | actin gamma 1 | -0.0292609 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0289037 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0285811 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0278985 |
| RASAL2 | RAS protein activator like 2 | -0.0275058 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0270122 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.026953 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0263512 |
| HLA-A | major histocompatibility complex, class I, A | -0.0257397 |
| RPL26 | ribosomal protein L26 | -0.0255833 |
| RPL11 | ribosomal protein L11 | -0.0247087 |
| RPS16 | ribosomal protein S16 | -0.0242238 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0238158 |
| TPI1 | triosephosphate isomerase 1 | -0.0237802 |
| BPTF | bromodomain PHD finger transcription factor | -0.0234559 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0234024 |
| UBAP2 | ubiquitin associated protein 2 | -0.0232163 |
| STC2 | stanniocalcin 2 | -0.0232013 |
| RPS3 | ribosomal protein S3 | -0.0228435 |
| S100A9 | S100 calcium binding protein A9 | -0.0226125 |
| EGR1 | early growth response 1 | -0.0226075 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0221567 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0219646 |
| RPL34 | ribosomal protein L34 | -0.0218391 |
| RPL8 | ribosomal protein L8 | -0.0217899 |
| RACK1 | receptor for activated C kinase 1 | -0.021785 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0217596 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0217036 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.021597 |
| RPLP2 | ribosomal protein, large, P2 | -0.0215658 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0213585 |
| CST3 | cystatin C | -0.0213531 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0213095 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0211024 |
| AEBP2 | AE binding protein 2 | -0.0208941 |
| PALLD | palladin, cytoskeletal associated protein | -0.0208286 |
| HMGA2 | high mobility group AT-hook 2 | -0.0208178 |
| PLIN2 | perilipin 2 | -0.0206613 |
| RPS24 | ribosomal protein S24 | -0.0205073 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0204342 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0199871 |
| RTN3 | reticulon 3 | -0.0197642 |
| RPLP1 | ribosomal protein, large, P1 | -0.0196091 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0193241 |
| JUN | jun proto-oncogene | -0.019154 |
| RANBP17 | RAN binding protein 17 | -0.0190108 |
| RPS23 | ribosomal protein S23 | -0.0189102 |
| FERMT2 | fermitin family member 2 | -0.0186061 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0185102 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0180978 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0180715 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0180379 |
| RPL37 | ribosomal protein L37 | -0.0179319 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0177928 |
