| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.0530425 |
| FLNA | filamin A, alpha | 0.0394955 |
| NPTN | neuroplastin | 0.0321067 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0266669 |
| NCKAP1 | NCK-associated protein 1 | 0.0258055 |
| TUFT1 | tuftelin 1 | 0.0244221 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0243294 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0236164 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0236159 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0231906 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0224956 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.022 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0212012 |
| SNX9 | sorting nexin 9 | 0.0211691 |
| MTMR3 | myotubularin related protein 3 | 0.0204301 |
| MEF2A | myocyte enhancer factor 2A | 0.020082 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0196316 |
| USP3 | ubiquitin specific peptidase 3 | 0.0196108 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0194421 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0191708 |
| HOXA3 | homeobox A3 | 0.0185839 |
| RPL3 | ribosomal protein L3 | 0.0182035 |
| ANXA11 | annexin A11 | 0.0181817 |
| HOXB3 | homeobox B3 | 0.018157 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0180384 |
| DIDO1 | death inducer-obliterator 1 | 0.0180125 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0172531 |
| ARRDC3 | arrestin domain containing 3 | 0.016975 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0168651 |
| MATR3 | matrin 3 | 0.0165793 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0165395 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0164014 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0163671 |
| MKRN1 | makorin ring finger protein 1 | 0.0163467 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0163369 |
| UBQLN1 | ubiquilin 1 | 0.0161488 |
| HOXB6 | homeobox B6 | 0.016082 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0159118 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0157539 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0157152 |
| HLA-C | major histocompatibility complex, class I, C | 0.015319 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0150915 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0150176 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0148981 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.014776 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0147546 |
| RBM33 | RNA binding motif protein 33 | 0.0145821 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0145256 |
| AFDN | afadin, adherens junction formation factor | 0.014511 |
| HBP1 | HMG-box transcription factor 1 | 0.0141089 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0134612 |
| TMEM39A | transmembrane protein 39A | 0.0133377 |
| TFG | TRK-fused gene | 0.0131517 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0131231 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0131173 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0129725 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0129592 |
| PCBP2 | poly(rC) binding protein 2 | 0.0128754 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0128723 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0127516 |
| FAR1 | fatty acyl CoA reductase 1 | 0.012741 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0125569 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0125285 |
| FAM168B | family with sequence similarity 168, member B | 0.0119527 |
| NXF1 | nuclear RNA export factor 1 | 0.0119003 |
| CDK17 | cyclin-dependent kinase 17 | 0.0118512 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0118247 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0116949 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.011672 |
| JUP | junction plakoglobin | 0.011666 |
| PER1 | period circadian clock 1 | 0.011654 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0116508 |
| CAPN5 | calpain 5 | 0.0116446 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0116155 |
| SUCO | SUN domain containing ossification factor | 0.0116093 |
| ELMO2 | engulfment and cell motility 2 | 0.011601 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0115775 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.011353 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0113044 |
| SEC24C | SEC24 family member C | 0.0112025 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0110161 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0109742 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0109719 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0108353 |
| ACVR1 | activin A receptor, type I | 0.0108335 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0108153 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0107709 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0106562 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0106432 |
| RPS18 | ribosomal protein S18 | 0.0106369 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0105778 |
| BSN | bassoon presynaptic cytomatrix protein | 0.0104951 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0104051 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0104 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0103763 |
| ZNF326 | zinc finger protein 326 | 0.0103661 |
| ACVR2A | activin A receptor, type IIA | 0.0102693 |
| MYO5B | myosin VB | 0.0101282 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.010118 |
| STRN4 | striatin, calmodulin binding protein 4 | 0.0101059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.285214 |
| FTL | ferritin, light polypeptide | -0.182906 |
| TMSB10 | thymosin beta 10 | -0.128836 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.123117 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0951819 |
| EHBP1 | EH domain binding protein 1 | -0.0908681 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0766044 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0726146 |
| RPL35A | ribosomal protein L35a | -0.0709713 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.068647 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0677162 |
| RPS6 | ribosomal protein S6 | -0.0649709 |
| BCL2L1 | BCL2-like 1 | -0.0607459 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0587342 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0570938 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0535899 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0527681 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0523558 |
| NEBL | nebulette | -0.0523082 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0522457 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0517421 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0515514 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0504577 |
| RPS21 | ribosomal protein S21 | -0.0500885 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0482444 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0478093 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0470602 |
| RPL12 | ribosomal protein L12 | -0.0467835 |
| GNAS | GNAS complex locus | -0.0467322 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0463423 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0451229 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.04351 |
| EPCAM | epithelial cell adhesion molecule | -0.0429274 |
| B2M | beta-2-microglobulin | -0.0419985 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0419657 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0417833 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0413939 |
| CUX1 | cut-like homeobox 1 | -0.0413654 |
| RPLP1 | ribosomal protein, large, P1 | -0.0410915 |
| RPLP2 | ribosomal protein, large, P2 | -0.0409299 |
| RPS13 | ribosomal protein S13 | -0.0406842 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0403948 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0402521 |
| IER3 | immediate early response 3 | -0.0401178 |
| KRT8 | keratin 8, type II | -0.0400805 |
| RPS27A | ribosomal protein S27a | -0.0399737 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0397361 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0391951 |
| RPL37A | ribosomal protein L37a | -0.0388668 |
| CADPS | Ca++-dependent secretion activator | -0.0385948 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0385776 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0383844 |
| LDHA | lactate dehydrogenase A | -0.0381954 |
| CD2AP | CD2-associated protein | -0.0380942 |
| PKP4 | plakophilin 4 | -0.0380645 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0377269 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0372031 |
| PLSCR1 | phospholipid scramblase 1 | -0.0371471 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0366248 |
| RPL23 | ribosomal protein L23 | -0.0366243 |
| KRT18 | keratin 18, type I | -0.0363389 |
| RPL31 | ribosomal protein L31 | -0.0363216 |
| RPL19 | ribosomal protein L19 | -0.0358776 |
| CCND1 | cyclin D1 | -0.0355446 |
| RPS24 | ribosomal protein S24 | -0.0355108 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0354591 |
| ETV6 | ets variant 6 | -0.0354157 |
| TOP1 | topoisomerase (DNA) I | -0.0354102 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0352614 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0351419 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0349912 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0348407 |
| CST3 | cystatin C | -0.034827 |
| NFIA | nuclear factor I/A | -0.0341916 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0341156 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0339646 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0339118 |
| RPL18 | ribosomal protein L18 | -0.0336803 |
| EXOC4 | exocyst complex component 4 | -0.0333796 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0330457 |
| S100A6 | S100 calcium binding protein A6 | -0.0328555 |
| JMJD1C | jumonji domain containing 1C | -0.0324408 |
| OXSR1 | oxidative stress responsive 1 | -0.0324263 |
| NF1 | neurofibromin 1 | -0.0324075 |
| AHNAK | AHNAK nucleoprotein | -0.0323736 |
| RPS5 | ribosomal protein S5 | -0.032344 |
| RPS19 | ribosomal protein S19 | -0.0320694 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.032038 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.03201 |
| SVIL | supervillin | -0.0317986 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0317832 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.031712 |
| USP34 | ubiquitin specific peptidase 34 | -0.0316968 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0316137 |
| MAP4 | microtubule-associated protein 4 | -0.0314067 |
| CDK13 | cyclin-dependent kinase 13 | -0.0312355 |
| PGK1 | phosphoglycerate kinase 1 | -0.0311225 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.030928 |
| PERP | PERP, TP53 apoptosis effector | -0.0308045 |
| CANX | calnexin | -0.0307798 |
