| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenytoin (sodium)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.0931236 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0777822 |
| RNF43 | ring finger protein 43 | 0.0738052 |
| RUNX2 | runt-related transcription factor 2 | 0.0719819 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0676592 |
| RPL3 | ribosomal protein L3 | 0.0653096 |
| LOC112694756 | uncharaterized LOC112694756 | 0.057602 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0560783 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0546201 |
| TXNRD1 | thioredoxin reductase 1 | 0.054399 |
| FOSL1 | FOS-like antigen 1 | 0.0540855 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0535789 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0532559 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0531912 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0522697 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.051978 |
| EGFR | epidermal growth factor receptor | 0.0515783 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0509597 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0490275 |
| EPHA2 | EPH receptor A2 | 0.0462348 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0451098 |
| OXR1 | oxidation resistance 1 | 0.0420813 |
| NUP58 | nucleoporin 58 | 0.0420315 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0410291 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0401045 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0385392 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0379938 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0377306 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0372865 |
| WAC | WW domain containing adaptor with coiled-coil | 0.03692 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0367571 |
| KRT18 | keratin 18, type I | 0.0362325 |
| CD46 | CD46 molecule, complement regulatory protein | 0.03524 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0347723 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0340688 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0340401 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0340055 |
| FAT1 | FAT atypical cadherin 1 | 0.0325637 |
| ANXA11 | annexin A11 | 0.0318408 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0313053 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.030992 |
| WDR45B | WD repeat domain 45B | 0.0309045 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0306654 |
| RNF145 | ring finger protein 145 | 0.0306046 |
| GDF15 | growth differentiation factor 15 | 0.0305782 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0304377 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0304055 |
| TPM4 | tropomyosin 4 | 0.0302832 |
| EWSR1 | EWS RNA-binding protein 1 | 0.029545 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0295275 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0294147 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0292184 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0290007 |
| RPS23 | ribosomal protein S23 | 0.0289913 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0282767 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0279956 |
| EDAR | ectodysplasin A receptor | 0.0275264 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0275123 |
| PLEC | plectin | 0.0275113 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0273183 |
| WDR43 | WD repeat domain 43 | 0.0272506 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0270637 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0268733 |
| FAF2 | Fas associated factor family member 2 | 0.0264219 |
| LAMC2 | laminin, gamma 2 | 0.0260643 |
| USP3 | ubiquitin specific peptidase 3 | 0.0259644 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0257578 |
| NFIA | nuclear factor I/A | 0.0257273 |
| CTSB | cathepsin B | 0.025664 |
| MACROH2A1 | macroH2A.1 histone | 0.0256558 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0256182 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0253768 |
| AXIN2 | axin 2 | 0.0252218 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.0252176 |
| ARRDC3 | arrestin domain containing 3 | 0.0252162 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0251043 |
| CABIN1 | calcineurin binding protein 1 | 0.0248262 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0247977 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0247634 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.024607 |
| HLA-A | major histocompatibility complex, class I, A | 0.0243217 |
| ATP11B | ATPase, class VI, type 11B | 0.0241284 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0239775 |
| EGR1 | early growth response 1 | 0.0238955 |
| YEATS2 | YEATS domain containing 2 | 0.0238778 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0234776 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0232578 |
| RPL30 | ribosomal protein L30 | 0.0232486 |
| UBE3C | ubiquitin protein ligase E3C | 0.0231964 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0231761 |
| CTBP2 | C-terminal binding protein 2 | 0.0231359 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0226369 |
| MED13 | mediator complex subunit 13 | 0.0224264 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0220799 |
| ACTN4 | actinin, alpha 4 | 0.0217781 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0217741 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0216899 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0212993 |
| NUP153 | nucleoporin 153kDa | 0.0211381 |
| TPD52L1 | tumor protein D52-like 1 | 0.0210469 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.155585 |
| PTMA | prothymosin, alpha | -0.134916 |
| TMSB10 | thymosin beta 10 | -0.131489 |
| RAD51B | RAD51 paralog B | -0.109943 |
| IER3 | immediate early response 3 | -0.101068 |
| HMGA2 | high mobility group AT-hook 2 | -0.100656 |
| RPS27A | ribosomal protein S27a | -0.0986804 |
| FHIT | fragile histidine triad | -0.0967024 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0845713 |
| AHNAK | AHNAK nucleoprotein | -0.0842902 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0788783 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0755892 |
| CANX | calnexin | -0.0736917 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0732936 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0722986 |
| LAMA4 | laminin, alpha 4 | -0.0698589 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0684492 |
| EMP1 | epithelial membrane protein 1 | -0.0681514 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0629588 |
| VCL | vinculin | -0.0625942 |
| EXOC4 | exocyst complex component 4 | -0.0586877 |
| RBM25 | RNA binding motif protein 25 | -0.0556918 |
| LAMB3 | laminin, beta 3 | -0.0541799 |
| RPS24 | ribosomal protein S24 | -0.052262 |
| RCOR1 | REST corepressor 1 | -0.0520372 |
| UBC | ubiquitin C | -0.0518849 |
| HDAC2 | histone deacetylase 2 | -0.0508538 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0496292 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0492274 |
| ENO1 | enolase 1, (alpha) | -0.0481972 |
| PHF14 | PHD finger protein 14 | -0.0481186 |
| RPL23 | ribosomal protein L23 | -0.0477569 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0435582 |
| EHBP1 | EH domain binding protein 1 | -0.0435122 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0431526 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0423735 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0417639 |
| RPS3 | ribosomal protein S3 | -0.0404934 |
| MT1X | metallothionein 1X | -0.040473 |
| GPHN | gephyrin | -0.0404373 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0404301 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0393872 |
| VMP1 | vacuole membrane protein 1 | -0.0393309 |
| RPL5 | ribosomal protein L5 | -0.0392368 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0387001 |
| ACTG1 | actin gamma 1 | -0.0386715 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0385851 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.03658 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0362929 |
| S100A10 | S100 calcium binding protein A10 | -0.0362617 |
| ATXN1 | ataxin 1 | -0.0360563 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0357278 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.035515 |
| MT2A | metallothionein 2A | -0.0354246 |
| CUX1 | cut-like homeobox 1 | -0.0344459 |
| ASPH | aspartate beta-hydroxylase | -0.0341937 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.03367 |
| PRELID2 | PRELI domain containing 2 | -0.0330562 |
| CDK13 | cyclin-dependent kinase 13 | -0.0324723 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0324056 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0323062 |
| ABR | active BCR-related | -0.0316015 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0311734 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0308691 |
| EFNB2 | ephrin-B2 | -0.0308641 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0298426 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0296634 |
| SET | SET nuclear proto-oncogene | -0.0294832 |
| RPL34 | ribosomal protein L34 | -0.0294404 |
| FOXN3 | forkhead box N3 | -0.0289832 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0288918 |
| KITLG | KIT ligand | -0.0288702 |
| RPL26 | ribosomal protein L26 | -0.0288367 |
| DIAPH2 | diaphanous-related formin 2 | -0.0287821 |
| SGMS2 | sphingomyelin synthase 2 | -0.0285991 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0279642 |
| CEP128 | centrosomal protein 128kDa | -0.0279273 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0278337 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0277599 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0276684 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0276119 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0274529 |
| GLCCI1 | glucocorticoid induced 1 | -0.0271829 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0270626 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0270366 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0266605 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0265582 |
| SMYD3 | SET and MYND domain containing 3 | -0.0264845 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.026467 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0264475 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0263496 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0262736 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0260818 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0259983 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0258971 |
| SDC4 | syndecan 4 | -0.0258469 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0257048 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0255829 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0253162 |
| GLG1 | golgi glycoprotein 1 | -0.0252454 |
