| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.175713 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.108072 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.106958 |
| RUNX1 | runt-related transcription factor 1 | 0.0939668 |
| PLEC | plectin | 0.0908392 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0873481 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0790326 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0773622 |
| HDAC4 | histone deacetylase 4 | 0.0743924 |
| PGK1 | phosphoglycerate kinase 1 | 0.0741371 |
| KRT18 | keratin 18, type I | 0.0733531 |
| ABHD2 | abhydrolase domain containing 2 | 0.072653 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0715907 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0694765 |
| ATXN1 | ataxin 1 | 0.0669927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0667451 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0654937 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0643789 |
| PROX1 | prospero homeobox 1 | 0.0637278 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0624506 |
| KIZ | kizuna centrosomal protein | 0.0620737 |
| ETNK1 | ethanolamine kinase 1 | 0.0582954 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0572381 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0563163 |
| AOPEP | aminopeptidase O (putative) | 0.0561836 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0557247 |
| ACTN4 | actinin, alpha 4 | 0.0556652 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0550039 |
| LMO7 | LIM domain 7 | 0.0547736 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0545589 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0543534 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0537981 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0533674 |
| ENO1 | enolase 1, (alpha) | 0.0523789 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0523481 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0519134 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0511063 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.050881 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0504779 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0504604 |
| ZNF292 | zinc finger protein 292 | 0.0502849 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0495148 |
| DSPP | dentin sialophosphoprotein | 0.0491677 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0490321 |
| TNS3 | tensin 3 | 0.0489026 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0477868 |
| SBF2 | SET binding factor 2 | 0.0467421 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0463013 |
| EFNB2 | ephrin-B2 | 0.0462313 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0460488 |
| DST | dystonin | 0.0455672 |
| VGLL4 | vestigial-like family member 4 | 0.0454874 |
| CMIP | c-Maf inducing protein | 0.0439366 |
| AFDN | afadin, adherens junction formation factor | 0.0434445 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0428792 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0428486 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.042026 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0420054 |
| ANLN | anillin, actin binding protein | 0.0409809 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0409348 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0408101 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0407804 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0395068 |
| ANXA2 | annexin A2 | 0.0394687 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0390157 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0389471 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0387314 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0385324 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0383299 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0382811 |
| RBM39 | RNA binding motif protein 39 | 0.0382626 |
| SVIL | supervillin | 0.0382505 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0379728 |
| NF1 | neurofibromin 1 | 0.037968 |
| UTRN | utrophin | 0.037856 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0377901 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0376603 |
| RPL3 | ribosomal protein L3 | 0.037055 |
| RBM26 | RNA binding motif protein 26 | 0.0369743 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0369337 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0368913 |
| FLNA | filamin A, alpha | 0.0368698 |
| NONO | non-POU domain containing, octamer-binding | 0.0365328 |
| PTEN | phosphatase and tensin homolog | 0.0364378 |
| CLTC | clathrin, heavy chain (Hc) | 0.0360099 |
| DIAPH3 | diaphanous-related formin 3 | 0.0360013 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0358202 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0356894 |
| PCBP2 | poly(rC) binding protein 2 | 0.0355779 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0353733 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0349753 |
| YEATS2 | YEATS domain containing 2 | 0.0348703 |
| CANX | calnexin | 0.0348187 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0346918 |
| YAP1 | Yes-associated protein 1 | 0.0345381 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0344252 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0339279 |
| TMEM123 | transmembrane protein 123 | 0.0338622 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.03372 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0336141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.110787 |
| PTMA | prothymosin, alpha | -0.099803 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.091962 |
| INTS6 | integrator complex subunit 6 | -0.0906594 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0802299 |
| TMSB10 | thymosin beta 10 | -0.0791501 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0759516 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0673647 |
| CCND1 | cyclin D1 | -0.0598743 |
| CDH13 | cadherin 13 | -0.0478432 |
| RPL35A | ribosomal protein L35a | -0.0475436 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0471816 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0452649 |
| ASPH | aspartate beta-hydroxylase | -0.0326593 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0323829 |
| FRMD5 | FERM domain containing 5 | -0.0313474 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0304638 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0295009 |
| UBAP2 | ubiquitin associated protein 2 | -0.0284266 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0278079 |
| RPS24 | ribosomal protein S24 | -0.0276495 |
| FTL | ferritin, light polypeptide | -0.0271639 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.026957 |
| MT2A | metallothionein 2A | -0.0268742 |
| CDK13 | cyclin-dependent kinase 13 | -0.0267941 |
| RPL23 | ribosomal protein L23 | -0.0263612 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0260282 |
| RBP1 | retinol binding protein 1, cellular | -0.0257167 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0255649 |
| CUX1 | cut-like homeobox 1 | -0.0251597 |
| NOP56 | NOP56 ribonucleoprotein | -0.0250039 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0248109 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0245008 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0231072 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0228826 |
| CD44 | CD44 molecule (Indian blood group) | -0.0219267 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | -0.0216866 |
| RPL9 | ribosomal protein L9 | -0.0212604 |
| ANXA3 | annexin A3 | -0.0209017 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0207742 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0203417 |
| EGR1 | early growth response 1 | -0.0202087 |
| IGF2 | insulin-like growth factor 2 | -0.0202038 |
| CCNL1 | cyclin L1 | -0.0201673 |
| FHIT | fragile histidine triad | -0.0200364 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.019796 |
| PCDH9 | protocadherin 9 | -0.0197401 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0197159 |
| RPS27A | ribosomal protein S27a | -0.0192568 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0191217 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0188971 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.018646 |
| NABP1 | nucleic acid binding protein 1 | -0.0185633 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0181537 |
| PUM3 | pumilio RNA binding family member 3 | -0.0178288 |
| CLSTN2 | calsyntenin 2 | -0.0178025 |
| COMMD10 | COMM domain containing 10 | -0.0177857 |
| IER3 | immediate early response 3 | -0.0173635 |
| MTAP | methylthioadenosine phosphorylase | -0.0171628 |
| DUSP6 | dual specificity phosphatase 6 | -0.0170175 |
| WDR43 | WD repeat domain 43 | -0.0169646 |
| NLK | nemo-like kinase | -0.0166655 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0165948 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0165441 |
| ZNF704 | zinc finger protein 704 | -0.0165414 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0165108 |
| MT1X | metallothionein 1X | -0.0164374 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0164059 |
| RPS25 | ribosomal protein S25 | -0.0163657 |
| TGFB1 | transforming growth factor, beta 1 | -0.0163606 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0160785 |
| TBC1D4 | TBC1 domain family, member 4 | -0.0159343 |
| RAB10 | RAB10, member RAS oncogene family | -0.0155213 |
| FUS | FUS RNA binding protein | -0.0154973 |
| RPL37A | ribosomal protein L37a | -0.0154945 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0154392 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0152726 |
| YBX3 | Y box binding protein 3 | -0.0152112 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0150547 |
| PUS7 | pseudouridylate synthase 7 (putative) | -0.0148375 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0147481 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0147372 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0147312 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0146116 |
| RCC1 | regulator of chromosome condensation 1 | -0.0145861 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0145041 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0144405 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0144139 |
| RCOR1 | REST corepressor 1 | -0.0144053 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0143916 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0143413 |
| CCDC138 | coiled-coil domain containing 138 | -0.0141453 |
| MYO1D | myosin ID | -0.0140725 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0140587 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0140378 |
| RPS11 | ribosomal protein S11 | -0.0139031 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0138855 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0138078 |
| E2F3 | E2F transcription factor 3 | -0.0137672 |
| TYW1B | tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) | -0.0137294 |
