| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenytoin (sodium) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenytoin (sodium)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.233903 |
| STC1 | stanniocalcin 1 | 0.14512 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.114706 |
| FAM13A | family with sequence similarity 13, member A | 0.11466 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0976203 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0898507 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0887262 |
| NDRG1 | N-myc downstream regulated 1 | 0.0851126 |
| ATP13A3 | ATPase type 13A3 | 0.0643465 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0642409 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0611913 |
| ANXA2 | annexin A2 | 0.0600765 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0591239 |
| MMP1 | matrix metallopeptidase 1 | 0.0555505 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0541862 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0541803 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.054023 |
| ADM | adrenomedullin | 0.0522334 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0513984 |
| HLA-C | major histocompatibility complex, class I, C | 0.0495999 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0491141 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.046067 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0458736 |
| HDLBP | high density lipoprotein binding protein | 0.0437803 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0428126 |
| FMNL2 | formin-like 2 | 0.0397088 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0386123 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.038344 |
| GOLGA4 | golgin A4 | 0.0381068 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0379601 |
| FLNA | filamin A, alpha | 0.0373923 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0361802 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0349416 |
| WDR45B | WD repeat domain 45B | 0.034055 |
| PDE8A | phosphodiesterase 8A | 0.0338934 |
| RPL3 | ribosomal protein L3 | 0.0333876 |
| RASA2 | RAS p21 protein activator 2 | 0.0326578 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0325715 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0316804 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0315462 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0312952 |
| LOXL2 | lysyl oxidase-like 2 | 0.0310356 |
| CLINT1 | clathrin interactor 1 | 0.0307723 |
| VIM | vimentin | 0.030772 |
| HELZ | helicase with zinc finger | 0.0304063 |
| ANXA5 | annexin A5 | 0.0302918 |
| USP3 | ubiquitin specific peptidase 3 | 0.0300367 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0298298 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0297715 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0290928 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0282728 |
| TNS1 | tensin 1 | 0.0281278 |
| SEC24D | SEC24 family member D | 0.0280761 |
| RPS3 | ribosomal protein S3 | 0.0280453 |
| CALR | calreticulin | 0.027807 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0274851 |
| PGM3 | phosphoglucomutase 3 | 0.0273454 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0270847 |
| YBX1 | Y box binding protein 1 | 0.0267521 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0264546 |
| NGLY1 | N-glycanase 1 | 0.0263818 |
| RNF145 | ring finger protein 145 | 0.0262557 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0262367 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0259928 |
| ARRDC3 | arrestin domain containing 3 | 0.0258366 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0257962 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.02542 |
| TPM3 | tropomyosin 3 | 0.025246 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0244545 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0244538 |
| SPAG9 | sperm associated antigen 9 | 0.024388 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0242769 |
| TMSB4X | thymosin beta 4, X-linked | 0.024107 |
| MSI2 | musashi RNA-binding protein 2 | 0.0237903 |
| RACK1 | receptor for activated C kinase 1 | 0.0233193 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0231391 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0229994 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0227167 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0223859 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0223042 |
| SEPTIN9 | septin 9 | 0.0221016 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0220221 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0219378 |
| RPL34 | ribosomal protein L34 | 0.021937 |
| CDC27 | cell division cycle 27 | 0.0217948 |
| LMNA | lamin A/C | 0.0216756 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0215034 |
| RRBP1 | ribosome binding protein 1 | 0.021403 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0212134 |
| MEIS1 | Meis homeobox 1 | 0.0211752 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0207553 |
| RPL4 | ribosomal protein L4 | 0.0207424 |
| CUL3 | cullin 3 | 0.0205689 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0205215 |
| LDHA | lactate dehydrogenase A | 0.0204382 |
| FAT1 | FAT atypical cadherin 1 | 0.0202734 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0201869 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0201452 |
| NUP58 | nucleoporin 58 | 0.0200577 |
| PLEC | plectin | 0.020015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.256969 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.134953 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0936568 |
| MT2A | metallothionein 2A | -0.0801844 |
| HLA-B | major histocompatibility complex, class I, B | -0.0755433 |
| COL1A1 | collagen, type I, alpha 1 | -0.0721964 |
| ASPH | aspartate beta-hydroxylase | -0.0632615 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0594083 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0525478 |
| TMSB10 | thymosin beta 10 | -0.0504162 |
| HMGA2 | high mobility group AT-hook 2 | -0.0462004 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0460083 |
| FTL | ferritin, light polypeptide | -0.0454412 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0445861 |
| VCL | vinculin | -0.0435157 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.041287 |
| CDH13 | cadherin 13 | -0.0406916 |
| MYO10 | myosin X | -0.0402651 |
| COL1A2 | collagen, type I, alpha 2 | -0.0396475 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0395986 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0395856 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392823 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0381223 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0375963 |
| FRMD4A | FERM domain containing 4A | -0.0373094 |
| DIAPH2 | diaphanous-related formin 2 | -0.0364943 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0357661 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0355067 |
| INTS6 | integrator complex subunit 6 | -0.034691 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0346862 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0341526 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0334258 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0331339 |
| B2M | beta-2-microglobulin | -0.0316888 |
| OXR1 | oxidation resistance 1 | -0.0312752 |
| RPS19 | ribosomal protein S19 | -0.0306734 |
| RPS6 | ribosomal protein S6 | -0.0305531 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0300028 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0282951 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0281942 |
| KIAA1549L | KIAA1549-like | -0.0270611 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0266226 |
| PRRX1 | paired related homeobox 1 | -0.0264136 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.025657 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0253656 |
| RIGI | RNA sensor RIG-I | -0.0252935 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0251301 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0244061 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.024211 |
| CDK6 | cyclin-dependent kinase 6 | -0.0240226 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0239084 |
| MED13L | mediator complex subunit 13-like | -0.0238713 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.023643 |
| GLIS3 | GLIS family zinc finger 3 | -0.0234572 |
| AHNAK | AHNAK nucleoprotein | -0.0227103 |
| RPS23 | ribosomal protein S23 | -0.022508 |
| JMJD1C | jumonji domain containing 1C | -0.0224285 |
| NBEAL1 | neurobeachin-like 1 | -0.0223352 |
| RPLP2 | ribosomal protein, large, P2 | -0.0222591 |
| BPTF | bromodomain PHD finger transcription factor | -0.021935 |
| FUS | FUS RNA binding protein | -0.0218075 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0216318 |
| TAOK3 | TAO kinase 3 | -0.0213077 |
| KLF12 | Kruppel-like factor 12 | -0.0211669 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0208796 |
| NABP1 | nucleic acid binding protein 1 | -0.0208684 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0205296 |
| RAD51B | RAD51 paralog B | -0.0204605 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0202971 |
| EMP1 | epithelial membrane protein 1 | -0.0202805 |
| RPS15 | ribosomal protein S15 | -0.020239 |
| FGF5 | fibroblast growth factor 5 | -0.0201093 |
| S100A10 | S100 calcium binding protein A10 | -0.0199969 |
| YAP1 | Yes-associated protein 1 | -0.0199867 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0195834 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0195277 |
| COL3A1 | collagen, type III, alpha 1 | -0.0195237 |
| EXOC4 | exocyst complex component 4 | -0.0194912 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0194412 |
| IPO9 | importin 9 | -0.0190455 |
| SNX14 | sorting nexin 14 | -0.0189671 |
| RPL31 | ribosomal protein L31 | -0.0188408 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0187892 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0187104 |
| SLC38A2 | solute carrier family 38, member 2 | -0.018709 |
| IL6 | interleukin 6 | -0.0186859 |
| CCDC102B | coiled-coil domain containing 102B | -0.0186753 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0185242 |
| CUX1 | cut-like homeobox 1 | -0.0184038 |
| CD44 | CD44 molecule (Indian blood group) | -0.0183987 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0183386 |
| ITGA1 | integrin, alpha 1 | -0.018329 |
| MYO1D | myosin ID | -0.0181198 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0177368 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0175346 |
| RPL28 | ribosomal protein L28 | -0.0173539 |
| RPLP1 | ribosomal protein, large, P1 | -0.0172607 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0172106 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0171783 |
| VCAN | versican | -0.0171273 |
