Phenytoin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5. (Chemical Entities of Biological Interest Ontology, CHEBI_8107)
External Link http://ctdbase.org/detail.go?type=chem&acc=D010672
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Genes

68 genes/proteins interacting with the chemical Phenytoin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACHE acetylcholinesterase (Yt blood group)
AHR aryl hydrocarbon receptor
AR androgen receptor
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
CALCA calcitonin-related polypeptide alpha
CAT catalase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CKM creatine kinase, muscle
CTSB cathepsin B
CTSL cathepsin L
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A cytochrome P450, family 3, subfamily A
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
FGFR2 fibroblast growth factor receptor 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GLUL glutamate-ammonia ligase
GSTM1 glutathione S-transferase mu 1
GUSB glucuronidase, beta
HLA-B major histocompatibility complex, class I, B
HMGB1 high mobility group box 1
HOXA2 homeobox A2
IFNG interferon, gamma
IL17A interleukin 17A
IL1B interleukin 1, beta
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MKI67 marker of proliferation Ki-67
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA1 nuclear receptor coactivator 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPRM1 opioid receptor, mu 1
PDGFB platelet-derived growth factor beta polypeptide
POR P450 (cytochrome) oxidoreductase
POU3F1 POU class 3 homeobox 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PTH parathyroid hormone
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SELE selectin E
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
TIMP1 TIMP metallopeptidase inhibitor 1
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1