Pheochromocytoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Pheochromocytomas (also known as chromaffin tumors) produce, store, and secrete catecholamines. Pheochromocytomas usually originate from the adrenal medulla but may also develop from chromaffin cells in or about sympathetic ganglia. A common symptom of pheochromocytoma is hypertension owing to release of catecholamines. (Human Phenotype Ontology, HP_0002666)
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Genes

1132 genes co-occuring with the disease Pheochromocytoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 3.841
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 3.814
RET ret proto-oncogene 3.492
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 3.438
TMEM127 transmembrane protein 127 3.432
SDHAF2 succinate dehydrogenase complex assembly factor 2 3.409
NGF nerve growth factor (beta polypeptide) 3.398
CHGA chromogranin A 3.343
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 3.34
NF1 neurofibromin 1 3.292
SYP synaptophysin 3.243
POMC proopiomelanocortin 3.0
FH fumarate hydratase 2.968
EPAS1 endothelial PAS domain protein 1 2.952
SST somatostatin 2.951
ADM adrenomedullin 2.942
PNMT phenylethanolamine N-methyltransferase 2.932
MEN1 multiple endocrine neoplasia I 2.891
ENO2 enolase 2 (gamma, neuronal) 2.877
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.847
TH tyrosine hydroxylase 2.758
REN renin 2.745
EGLN1 egl-9 family hypoxia-inducible factor 1 2.691
MAX MYC associated factor X 2.617
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.615
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 2.592
TP53 tumor protein p53 2.573
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.546
KIF1B kinesin family member 1B 2.538
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.537
SSTR2 somatostatin receptor 2 2.514
SDHAF1 succinate dehydrogenase complex assembly factor 1 2.495
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.469
VIP vasoactive intestinal peptide 2.456
NCAM1 neural cell adhesion molecule 1 2.446
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.436
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.434
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.433
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.43
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.423
CSDE1 cold shock domain containing E1, RNA-binding 2.42
ELOC elongin C 2.415
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.39
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 2.385
BCL2 B-cell CLL/lymphoma 2 2.381
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.38
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.379
INS insulin 2.355
HRAS Harvey rat sarcoma viral oncogene homolog 2.352
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.347
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.321
EGLN2 egl-9 family hypoxia-inducible factor 2 2.314
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.309
ELOB elongin B 2.305
ATRX alpha thalassemia/mental retardation syndrome X-linked 2.29
GCG glucagon 2.275
GAST gastrin 2.272
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.259
MAOB monoamine oxidase B 2.255
NPY neuropeptide Y 2.253
CRH corticotropin releasing hormone 2.246
CHGB chromogranin B 2.241
BDNF brain-derived neurotrophic factor 2.239
MAOA monoamine oxidase A 2.23
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.227
EGLN3 egl-9 family hypoxia-inducible factor 3 2.222
PPY pancreatic polypeptide 2.217
CALCRL calcitonin receptor-like 2.216
CD34 CD34 molecule 2.216
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.216
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.213
ACTB actin, beta 2.212
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 2.209
PTEN phosphatase and tensin homolog 2.204
CUL2 cullin 2 2.203
EGF epidermal growth factor 2.195
SCG2 secretogranin II 2.191
PTH parathyroid hormone 2.187
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.175
CALB2 calbindin 2 2.171
GDNF glial cell derived neurotrophic factor 2.17
CYCS cytochrome c, somatic 2.165
NGFR nerve growth factor receptor 2.163
PXDN peroxidasin 2.16
PXDNL peroxidasin-like 2.16
CREB1 cAMP responsive element binding protein 1 2.158
JUN jun proto-oncogene 2.157
ALB albumin 2.156
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.155
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.147
EIF5B eukaryotic translation initiation factor 5B 2.146
MAPK3 mitogen-activated protein kinase 3 2.137
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 2.135
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.133
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.133
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 2.125
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.122
BAX BCL2-associated X protein 2.121
SSTR5 somatostatin receptor 5 2.12
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.12
EGFR epidermal growth factor receptor 2.097
PAX8 paired box 8 2.096
SSTR1 somatostatin receptor 1 2.092
MAML3 mastermind-like 3 (Drosophila) 2.088
GATA3 GATA binding protein 3 2.085
IL6 interleukin 6 2.083
APP amyloid beta (A4) precursor protein 2.074
ANO1 anoctamin 1, calcium activated chloride channel 2.074
ACE angiotensin I converting enzyme 2.061
SDHAF4 succinate dehydrogenase complex assembly factor 4 2.058
EPO erythropoietin 2.05
PRL prolactin 2.049
CD274 CD274 molecule 2.044
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.043
CDKN2A cyclin-dependent kinase inhibitor 2A 2.038
ARNT aryl hydrocarbon receptor nuclear translocator 2.036
CD8A CD8a molecule 2.035
SOX10 SRY (sex determining region Y)-box 10 2.034
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.032
IGF1 insulin-like growth factor 1 (somatomedin C) 2.03
RAMP3 receptor (G protein-coupled) activity modifying protein 3 2.03
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.029
KRT7 keratin 7, type II 2.026
KRAS Kirsten rat sarcoma viral oncogene homolog 2.024
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.011
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.994
TG thyroglobulin 1.991
FGF2 fibroblast growth factor 2 (basic) 1.988
MME membrane metallo-endopeptidase 1.987
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.985
TGFB1 transforming growth factor, beta 1 1.981
CA9 carbonic anhydrase IX 1.972
CCK cholecystokinin 1.97
IGF2 insulin-like growth factor 2 1.969
ANXA5 annexin A5 1.965
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 1.965
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.958
NF2 neurofibromin 2 (merlin) 1.957
GHRH growth hormone releasing hormone 1.956
FOS FBJ murine osteosarcoma viral oncogene homolog 1.953
CDC73 cell division cycle 73 1.952
TERT telomerase reverse transcriptase 1.952
TNF tumor necrosis factor 1.946
ERBB2 erb-b2 receptor tyrosine kinase 2 1.943
GSK3B glycogen synthase kinase 3 beta 1.939
SDHAF3 succinate dehydrogenase complex assembly factor 3 1.939
CCND1 cyclin D1 1.938
CD4 CD4 molecule 1.933
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.927
INSM1 insulinoma-associated 1 1.913
IL1B interleukin 1, beta 1.91
TCHP trichoplein, keratin filament binding 1.904
COMT catechol-O-methyltransferase 1.901
FLCN folliculin 1.901
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.896
TFE3 transcription factor binding to IGHM enhancer 3 1.893
HMOX1 heme oxygenase 1 1.89
FGFR1 fibroblast growth factor receptor 1 1.888
PHOX2B paired-like homeobox 2b 1.885
NPPA natriuretic peptide A 1.885
TSC2 tuberous sclerosis 2 1.884
ACHE acetylcholinesterase (Yt blood group) 1.884
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.883
NKX2-1 NK2 homeobox 1 1.881
HIF3A hypoxia inducible factor 3, alpha subunit 1.88
H3-3B H3.3 histone B 1.88
NTF3 neurotrophin 3 1.871
ESR1 estrogen receptor 1 1.871
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.868
LDHA lactate dehydrogenase A 1.864
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.863
PENK proenkephalin 1.858
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.857
BRCA1 breast cancer 1, early onset 1.856
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.853
MSH2 mutS homolog 2 1.849
CHAT choline O-acetyltransferase 1.847
GFAP glial fibrillary acidic protein 1.846
SSTR3 somatostatin receptor 3 1.844
NFE2L2 nuclear factor, erythroid 2-like 2 1.835
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.833
KDR kinase insert domain receptor 1.833
VHLL von Hippel-Lindau tumor suppressor-like 1.832
MSH6 mutS homolog 6 1.828
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.822
MLH1 mutL homolog 1 1.82
SSTR4 somatostatin receptor 4 1.818
KRT20 keratin 20, type I 1.818
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.81
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.81
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.805
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.804
BCL2L1 BCL2-like 1 1.801
CALML3 calmodulin-like 3 1.8
PECAM1 platelet/endothelial cell adhesion molecule 1 1.798
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.796
FN1 fibronectin 1 1.795
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.791
CALML4 calmodulin-like 4 1.79
GAP43 growth associated protein 43 1.79
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.789
CALML6 calmodulin-like 6 1.788
CALML5 calmodulin-like 5 1.785
GNAS GNAS complex locus 1.78
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 1.767
GPR101 G protein-coupled receptor 101 1.765
KEAP1 kelch-like ECH-associated protein 1 1.761
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.76
MAP2 microtubule-associated protein 2 1.758
ADRB2 adrenoceptor beta 2, surface 1.757
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.757
IFNG interferon, gamma 1.756
IGF1R insulin-like growth factor 1 receptor 1.756
H3C12 H3 clustered histone 12 1.755
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 1.753
TAC1 tachykinin, precursor 1 1.752
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.751
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 1.747
DAXX death-domain associated protein 1.747
PKM pyruvate kinase, muscle 1.745
PARP1 poly (ADP-ribose) polymerase 1 1.745
BRCA2 breast cancer 2, early onset 1.745
CDK4 cyclin-dependent kinase 4 1.74
PDCD1 programmed cell death 1 1.739
H3-4 H3.4 histone, cluster member 1.738
PPARG peroxisome proliferator-activated receptor gamma 1.733
H3-5 H3.5 histone 1.733
H3C13 H3 clustered histone 13 1.733
GPX2 glutathione peroxidase 2 1.726
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.725
DNAH8 dynein, axonemal, heavy chain 8 1.724
GPX7 glutathione peroxidase 7 1.724
MAP2K1 mitogen-activated protein kinase kinase 1 1.722
GPX3 glutathione peroxidase 3 1.719
GFRA1 GDNF family receptor alpha 1 1.717
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.716
GPX8 glutathione peroxidase 8 (putative) 1.714
BACE1 beta-site APP-cleaving enzyme 1 1.711
GPX6 glutathione peroxidase 6 1.711
CD99 CD99 molecule 1.709
GPX5 glutathione peroxidase 5 1.708
MXD1 MAX dimerization protein 1 1.706
NPPB natriuretic peptide B 1.706
CHEK2 checkpoint kinase 2 1.705
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.704
SETD2 SET domain containing 2 1.702
ATM ATM serine/threonine kinase 1.702
ACO1 aconitase 1, soluble 1.699
RHOA ras homolog family member A 1.698
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.695
HSPA4 heat shock 70kDa protein 4 1.695
ISL1 ISL LIM homeobox 1 1.694
GRP gastrin-releasing peptide 1.694
GAL galanin/GMAP prepropeptide 1.694
ACO2 aconitase 2, mitochondrial 1.693
SIRT1 sirtuin 1 1.69
EDN1 endothelin 1 1.687
TGFA transforming growth factor, alpha 1.685
CD99L2 CD99 molecule-like 2 1.683
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.674
ALK anaplastic lymphoma receptor tyrosine kinase 1.673
NTS neurotensin 1.671
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.667
SUCNR1 succinate receptor 1 1.664
MGMT O-6-methylguanine-DNA methyltransferase 1.663
EGR1 early growth response 1 1.662
LAG3 lymphocyte-activation gene 3 1.661
CD68 CD68 molecule 1.657
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.657
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.655
MITF microphthalmia-associated transcription factor 1.653
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.652
PSPN persephin 1.651
ADM2 adrenomedullin 2 1.65
FLT1 fms-related tyrosine kinase 1 1.642
CRP C-reactive protein, pentraxin-related 1.64
ADORA2A adenosine A2a receptor 1.639
SCT secretin 1.638
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.635
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.635
PC pyruvate carboxylase 1.633
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.632
EP300 E1A binding protein p300 1.631
SNAI1 snail family zinc finger 1 1.63
FGF3 fibroblast growth factor 3 1.626
SYN1 synapsin I 1.617
FGF4 fibroblast growth factor 4 1.613
FGF8 fibroblast growth factor 8 (androgen-induced) 1.612
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.612
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.61
ARMC5 armadillo repeat containing 5 1.608
STK11 serine/threonine kinase 11 1.605
MMP9 matrix metallopeptidase 9 1.605
ASCL1 achaete-scute family bHLH transcription factor 1 1.605
CDC42 cell division cycle 42 1.603
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.603
KNG1 kininogen 1 1.6
PDCD1LG2 programmed cell death 1 ligand 2 1.599
TXN thioredoxin 1.599
SCG3 secretogranin III 1.598
CKB creatine kinase, brain 1.592
CKMT1B creatine kinase, mitochondrial 1B 1.59
DICER1 dicer 1, ribonuclease type III 1.59
MYH14 myosin, heavy chain 14, non-muscle 1.589
AIP aryl hydrocarbon receptor interacting protein 1.588
MAPK8 mitogen-activated protein kinase 8 1.587
KMT2D lysine (K)-specific methyltransferase 2D 1.587
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.586
IL10 interleukin 10 1.585
BECN1 beclin 1, autophagy related 1.584
H3-3A H3.3 histone A 1.584
FGF18 fibroblast growth factor 18 1.583
TET2 tet methylcytosine dioxygenase 2 1.583
NES nestin 1.583
AFP alpha-fetoprotein 1.582
FGF22 fibroblast growth factor 22 1.582
MUTYH mutY homolog 1.58
EWSR1 EWS RNA-binding protein 1 1.579
FGF9 fibroblast growth factor 9 1.579
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.579
CD44 CD44 molecule (Indian blood group) 1.579
JAK2 Janus kinase 2 1.578
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.578
CDX2 caudal type homeobox 2 1.578
MYOG myogenin (myogenic factor 4) 1.578
MET MET proto-oncogene, receptor tyrosine kinase 1.577
AVP arginine vasopressin 1.576
MB myoglobin 1.575
HTT huntingtin 1.575
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.575
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.574
FGF6 fibroblast growth factor 6 1.574
FGF17 fibroblast growth factor 17 1.573
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.573
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 1.573
AR androgen receptor 1.572
FGF10 fibroblast growth factor 10 1.571
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 1.571
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 1.57
FGF16 fibroblast growth factor 16 1.569
FGF20 fibroblast growth factor 20 1.567
USP8 ubiquitin specific peptidase 8 1.567
PGR progesterone receptor 1.566
ADRB3 adrenoceptor beta 3 1.565
FGF5 fibroblast growth factor 5 1.564
BCHE butyrylcholinesterase 1.564
HAVCR2 hepatitis A virus cellular receptor 2 1.561
CKM creatine kinase, muscle 1.561
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.56
NTF4 neurotrophin 4 1.559
PBRM1 polybromo 1 1.559
EPCAM epithelial cell adhesion molecule 1.558
PDE11A phosphodiesterase 11A 1.557
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.556
PTPRC protein tyrosine phosphatase, receptor type, C 1.556
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 1.554
VGF VGF nerve growth factor inducible 1.553
HDAC9 histone deacetylase 9 1.552
FGF7 fibroblast growth factor 7 1.552
IAPP islet amyloid polypeptide 1.552
ACLY ATP citrate lyase 1.55
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.547
MAPK1 mitogen-activated protein kinase 1 1.547
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.547
INSR insulin receptor 1.545
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.543
WT1 Wilms tumor 1 1.543
CDK5 cyclin-dependent kinase 5 1.542
CASR calcium-sensing receptor 1.539
PINK1 PTEN induced putative kinase 1 1.538
GLS glutaminase 1.536
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.535
NRTN neurturin 1.534
FLT3 fms-related tyrosine kinase 3 1.533
PTHLH parathyroid hormone-like hormone 1.532
EPOR erythropoietin receptor 1.529
DRD2 dopamine receptor D2 1.529
CXCR4 chemokine (C-X-C motif) receptor 4 1.529
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.528
CS citrate synthase 1.528
PSEN1 presenilin 1 1.527
KDM4A lysine (K)-specific demethylase 4A 1.521
CXCL8 chemokine (C-X-C motif) ligand 8 1.519
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.516
PDYN prodynorphin 1.511
PRDM16 PR domain containing 16 1.51
IL2 interleukin 2 1.509
PTCH1 patched 1 1.499
PRKN parkin RBR E3 ubiquitin protein ligase 1.499
GRB2 growth factor receptor-bound protein 2 1.497
ARTN artemin 1.496
CCL2 chemokine (C-C motif) ligand 2 1.496
TBX19 T-box 19 1.495
CDK1 cyclin-dependent kinase 1 1.494
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.489
SOX2 SRY (sex determining region Y)-box 2 1.489
SNAP25 synaptosomal-associated protein, 25kDa 1.488
LEP leptin 1.487
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.482
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.48
CDK2 cyclin-dependent kinase 2 1.477
IL1A interleukin 1, alpha 1.474
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.474
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.472
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.472
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.469
KRT8 keratin 8, type II 1.469
E2F1 E2F transcription factor 1 1.469
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.466
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.464
GSR glutathione reductase 1.46
MAPK14 mitogen-activated protein kinase 14 1.459
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.459
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 1.458
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.458
PALB2 partner and localizer of BRCA2 1.453
NQO1 NAD(P)H dehydrogenase, quinone 1 1.45
BIRC5 baculoviral IAP repeat containing 5 1.45
CANX calnexin 1.449
PDE8B phosphodiesterase 8B 1.449
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.449
ADRB1 adrenoceptor beta 1 1.448
VIPR1 vasoactive intestinal peptide receptor 1 1.447
SIGLEC15 sialic acid binding Ig-like lectin 15 1.446
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.444
PCNA proliferating cell nuclear antigen 1.441
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.441
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 1.44
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.439
PHGDH phosphoglycerate dehydrogenase 1.439
GLS2 glutaminase 2 (liver, mitochondrial) 1.439
MMP2 matrix metallopeptidase 2 1.438
SYT1 synaptotagmin I 1.436
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.436
NKAPD1 NKAP domain containing 1 1.435
SOS1 son of sevenless homolog 1 (Drosophila) 1.434
SNAI2 snail family zinc finger 2 1.434
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.432
DLG4 discs, large homolog 4 (Drosophila) 1.429
PTK2 protein tyrosine kinase 2 1.429
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 1.429
SNED1 sushi, nidogen and EGF-like domains 1 1.428
PGK1 phosphoglycerate kinase 1 1.427
TLR4 toll-like receptor 4 1.426
FDX1 ferredoxin 1 1.425
LOX lysyl oxidase 1.425
PLD2 phospholipase D2 1.423
MAPT microtubule-associated protein tau 1.423
CDK6 cyclin-dependent kinase 6 1.42
TFRC transferrin receptor 1.418
NOTCH1 notch 1 1.416
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.416
TP53I13 tumor protein p53 inducible protein 13 1.413
SLC16A4 solute carrier family 16, member 4 1.412
GLP1R glucagon-like peptide 1 receptor 1.412
DNTT DNA nucleotidylexotransferase 1.411
SHH sonic hedgehog 1.41
SMAD4 SMAD family member 4 1.409
KRT19 keratin 19, type I 1.404
HK2 hexokinase 2 1.402
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.402
TUBB3 tubulin, beta 3 class III 1.402
TRDMT1 tRNA aspartic acid methyltransferase 1 1.4
TFAM transcription factor A, mitochondrial 1.394
TYR tyrosinase 1.393
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.392
PLK1 polo-like kinase 1 1.39
CFL1 cofilin 1 (non-muscle) 1.39
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 1.389
CALD1 caldesmon 1 1.389
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.388
CFL2 cofilin 2 (muscle) 1.386
VIPR2 vasoactive intestinal peptide receptor 2 1.385
ARID1A AT rich interactive domain 1A (SWI-like) 1.38
KRT5 keratin 5, type II 1.379
YAP1 Yes-associated protein 1 1.379
PLEK pleckstrin 1.377
TET1 tet methylcytosine dioxygenase 1 1.376
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.376
POU5F1 POU class 5 homeobox 1 1.375
SOD2 superoxide dismutase 2, mitochondrial 1.374
PLEK2 pleckstrin 2 1.374
FGFR3 fibroblast growth factor receptor 3 1.371
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.37
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.37
VDAC1 voltage-dependent anion channel 1 1.37
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.368
FOXO3 forkhead box O3 1.366
DLK1 delta-like 1 homolog (Drosophila) 1.366
ISCU iron-sulfur cluster assembly enzyme 1.365
SCO2 SCO2 cytochrome c oxidase assembly protein 1.365
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.364
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.364
NCOA4 nuclear receptor coactivator 4 1.362
ZEB1 zinc finger E-box binding homeobox 1 1.361
SOD1 superoxide dismutase 1, soluble 1.361
GLB1 galactosidase, beta 1 1.361
GCM2 glial cells missing homolog 2 (Drosophila) 1.361
VIM vimentin 1.361
TSC1 tuberous sclerosis 1 1.358
VCL vinculin 1.358
XBP1 X-box binding protein 1 1.357
SPRED1 sprouty-related, EVH1 domain containing 1 1.357
APAF1 apoptotic peptidase activating factor 1 1.357
FGF13 fibroblast growth factor 13 1.356
ERN1 endoplasmic reticulum to nucleus signaling 1 1.356
CAV1 caveolin 1, caveolae protein, 22kDa 1.355
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.354
IFNA1 interferon, alpha 1 1.354
CSF1R colony stimulating factor 1 receptor 1.351
CNTF ciliary neurotrophic factor 1.351
NEUROD1 neuronal differentiation 1 1.351
FOXO1 forkhead box O1 1.35
BARD1 BRCA1 associated RING domain 1 1.348
POTEF POTE ankyrin domain family, member F 1.347
MYOD1 myogenic differentiation 1 1.346
DDIT3 DNA-damage-inducible transcript 3 1.345
KLK3 kallikrein-related peptidase 3 1.345
FGFR2 fibroblast growth factor receptor 2 1.344
UTS2 urotensin 2 1.344
LGALS3 lectin, galactoside-binding, soluble, 3 1.342
NANOG Nanog homeobox 1.341
HDAC1 histone deacetylase 1 1.341
NOS3 nitric oxide synthase 3 (endothelial cell) 1.341
CCNL2 cyclin L2 1.341
STX1A syntaxin 1A (brain) 1.341
PPARA peroxisome proliferator-activated receptor alpha 1.34
APOE apolipoprotein E 1.339
SQSTM1 sequestosome 1 1.339
RABIF RAB interacting factor 1.337
KDM4B lysine (K)-specific demethylase 4B 1.336
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.335
PARK7 parkinson protein 7 1.334
IFNA2 interferon, alpha 2 1.332
CREBBP CREB binding protein 1.332
SIRT3 sirtuin 3 1.331
CD276 CD276 molecule 1.331
KITLG KIT ligand 1.328
EDNRB endothelin receptor type B 1.327
GALR2 galanin receptor 2 1.326
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.326
PCSK5 proprotein convertase subtilisin/kexin type 5 1.325
FRS2 fibroblast growth factor receptor substrate 2 1.325
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.325
TWIST1 twist family bHLH transcription factor 1 1.324
CYBB cytochrome b-245, beta polypeptide 1.323
MFN2 mitofusin 2 1.322
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.321
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 1.32
CPE carboxypeptidase E 1.32
UBTF upstream binding transcription factor, RNA polymerase I 1.318
ULK1 unc-51 like autophagy activating kinase 1 1.318
GALR1 galanin receptor 1 1.318
RAB3A RAB3A, member RAS oncogene family 1.318
CDKN3 cyclin-dependent kinase inhibitor 3 1.317
DNM1L dynamin 1-like 1.317
MMEL1 membrane metallo-endopeptidase-like 1 1.316
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.315
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.315
SLC49A4 solute carrier family 49 member 4 1.315
MCL1 myeloid cell leukemia 1 1.313
LGALS4 lectin, galactoside-binding, soluble, 4 1.313
ADIPOQ adiponectin, C1Q and collagen domain containing 1.313
FTO fat mass and obesity associated 1.311
PROM1 prominin 1 1.31
SP1 Sp1 transcription factor 1.309
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.308
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.308
IDO1 indoleamine 2,3-dioxygenase 1 1.307
TWSG1 twisted gastrulation BMP signaling modulator 1 1.306
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 1.305
CD86 CD86 molecule 1.304
OXT oxytocin/neurophysin I prepropeptide 1.302
CCDC6 coiled-coil domain containing 6 1.301
FOXM1 forkhead box M1 1.3
REST RE1-silencing transcription factor 1.3
KDM6B lysine (K)-specific demethylase 6B 1.3
ATF6 activating transcription factor 6 1.299
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 1.297
CALCA calcitonin-related polypeptide alpha 1.296
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.296
PAM peptidylglycine alpha-amidating monooxygenase 1.294
JUND jun D proto-oncogene 1.292
ESR2 estrogen receptor 2 (ER beta) 1.29
MAPK7 mitogen-activated protein kinase 7 1.29
XDH xanthine dehydrogenase 1.289
TIGAR TP53 induced glycolysis regulatory phosphatase 1.288
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.288
ARRB2 arrestin, beta 2 1.287
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.287
NPPC natriuretic peptide C 1.287
AGTR1 angiotensin II receptor, type 1 1.287
PTK2B protein tyrosine kinase 2 beta 1.287
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.286
GFRA4 GDNF family receptor alpha 4 1.286
CD163 CD163 molecule 1.286
STAT5B signal transducer and activator of transcription 5B 1.285
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.284
MAP1B microtubule-associated protein 1B 1.282
BMP7 bone morphogenetic protein 7 1.282
IL4 interleukin 4 1.282
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 1.281
PFKM phosphofructokinase, muscle 1.28
CCNB1 cyclin B1 1.28
GIPR gastric inhibitory polypeptide receptor 1.28
MXI1 MAX interactor 1, dimerization protein 1.279
IFNA13 interferon, alpha 13 1.279
GRPR gastrin-releasing peptide receptor 1.277
PYY peptide YY 1.274
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.274
MMUT methylmalonyl-CoA mutase 1.274
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.273
GCLC glutamate-cysteine ligase, catalytic subunit 1.273
IFNA17 interferon, alpha 17 1.273
USP48 ubiquitin specific peptidase 48 1.271
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.27
GLUL glutamate-ammonia ligase 1.269
CD177 CD177 molecule 1.269
CUL3 cullin 3 1.269
KIF5B kinesin family member 5B 1.269
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.268
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.266
NEFL neurofilament, light polypeptide 1.265
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.264
IFNA16 interferon, alpha 16 1.264
ETV6 ets variant 6 1.263
IFNA6 interferon, alpha 6 1.262
IFNA8 interferon, alpha 8 1.262
IFNA5 interferon, alpha 5 1.261
MAPRE3 microtubule-associated protein, RP/EB family, member 3 1.26
IFNA21 interferon, alpha 21 1.258
CCKBR cholecystokinin B receptor 1.258
RHOT1 ras homolog family member T1 1.258
IFNA7 interferon, alpha 7 1.258
IFNA10 interferon, alpha 10 1.258
IFNA14 interferon, alpha 14 1.258
ICAM1 intercellular adhesion molecule 1 1.256
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.256
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 1.256
IFNA4 interferon, alpha 4 1.252
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 1.251
TNNI3 troponin I type 3 (cardiac) 1.251
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.25
STAT5A signal transducer and activator of transcription 5A 1.249
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 1.247
RAB5A RAB5A, member RAS oncogene family 1.247
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 1.247
TKFC triokinase/FMN cyclase 1.247
USP33 ubiquitin specific peptidase 33 1.246
FLT4 fms-related tyrosine kinase 4 1.246
TTN titin 1.246
PLCG1 phospholipase C, gamma 1 1.246
PAX3 paired box 3 1.245
MAPK12 mitogen-activated protein kinase 12 1.243
LONP1 lon peptidase 1, mitochondrial 1.243
LZTR1 leucine-zipper-like transcription regulator 1 1.242
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.242
RAB11A RAB11A, member RAS oncogene family 1.242
AURKA aurora kinase A 1.241
GRK2 G protein-coupled receptor kinase 2 1.241
PRKCA protein kinase C, alpha 1.239
MAPK11 mitogen-activated protein kinase 11 1.237
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.236
RHEB Ras homolog enriched in brain 1.235
RYR2 ryanodine receptor 2 (cardiac) 1.235
FGF1 fibroblast growth factor 1 (acidic) 1.234
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 1.234
KDM5C lysine (K)-specific demethylase 5C 1.233
TFEB transcription factor EB 1.233
ENG endoglin 1.231
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1.231
FGFR4 fibroblast growth factor receptor 4 1.23
SMAD3 SMAD family member 3 1.229
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.227
NRG1 neuregulin 1 1.227
GCLM glutamate-cysteine ligase, modifier subunit 1.227
PHOX2A paired-like homeobox 2a 1.226
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 1.226
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 1.226
SV2A synaptic vesicle glycoprotein 2A 1.222
ANXA8 annexin A8 1.222
NDUFA4 NDUFA4, mitochondrial complex associated 1.222
PTTG1 pituitary tumor-transforming 1 1.222
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.221
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 1.221
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 1.22
ARRB1 arrestin, beta 1 1.22
PRDM2 PR domain containing 2, with ZNF domain 1.219
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.219
ENO1 enolase 1, (alpha) 1.218
RYR1 ryanodine receptor 1 (skeletal) 1.218
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.218
NOX4 NADPH oxidase 4 1.217
NFE2 nuclear factor, erythroid 2 1.217
HCRTR1 hypocretin (orexin) receptor 1 1.217
DLAT dihydrolipoamide S-acetyltransferase 1.216
PRKCD protein kinase C, delta 1.216
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.215
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.215
KDM6A lysine (K)-specific demethylase 6A 1.215
RPTOR regulatory associated protein of MTOR, complex 1 1.215
HNF4A hepatocyte nuclear factor 4, alpha 1.215
GPX4 glutathione peroxidase 4 1.215
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 1.214
D2HGDH D-2-hydroxyglutarate dehydrogenase 1.214
FYN FYN proto-oncogene, Src family tyrosine kinase 1.214
AXL AXL receptor tyrosine kinase 1.213
NOS1 nitric oxide synthase 1 (neuronal) 1.213
KAT2B K(lysine) acetyltransferase 2B 1.213
TBL1X transducin (beta)-like 1X-linked 1.213
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.212
BPGM 2,3-bisphosphoglycerate mutase 1.212
LMNA lamin A/C 1.21
PXN paxillin 1.21
BMP2 bone morphogenetic protein 2 1.21
FANCD2 Fanconi anemia, complementation group D2 1.21
CCNA2 cyclin A2 1.209
GPR182 G protein-coupled receptor 182 1.209
HDAC2 histone deacetylase 2 1.208
GHRL ghrelin/obestatin prepropeptide 1.208
VSIG4 V-set and immunoglobulin domain containing 4 1.207
SUCLG1 succinate-CoA ligase, alpha subunit 1.207
B2M beta-2-microglobulin 1.206
KRT18 keratin 18, type I 1.205
GATA2 GATA binding protein 2 1.205
CXCL12 chemokine (C-X-C motif) ligand 12 1.204
ACSS2 acyl-CoA synthetase short-chain family member 2 1.203
CD40 CD40 molecule, TNF receptor superfamily member 5 1.203
FASLG Fas ligand (TNF superfamily, member 6) 1.203
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.201
UTS2R urotensin 2 receptor 1.2
ALKBH5 AlkB family member 5, RNA demethylase 1.199
ATG5 autophagy related 5 1.199
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.195
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.194
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.193
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.193
SYN2 synapsin II 1.191
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.191
ODC1 ornithine decarboxylase 1 1.19
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.19
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.19
MERTK MER proto-oncogene, tyrosine kinase 1.19
KAT2A K(lysine) acetyltransferase 2A 1.189
L1CAM L1 cell adhesion molecule 1.189
SATB2 SATB homeobox 2 1.189
EDN3 endothelin 3 1.188
VCAM1 vascular cell adhesion molecule 1 1.188
ERBB3 erb-b2 receptor tyrosine kinase 3 1.188
RALGDS ral guanine nucleotide dissociation stimulator 1.188
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.186
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.185
KDM1A lysine (K)-specific demethylase 1A 1.183
CTCF CCCTC-binding factor (zinc finger protein) 1.182
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.182
MKI67 marker of proliferation Ki-67 1.182
CALCB calcitonin-related polypeptide beta 1.182
CCL5 chemokine (C-C motif) ligand 5 1.18
LIAS lipoic acid synthetase 1.179
ZNF367 zinc finger protein 367 1.179
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 1.179
HNF1A HNF1 homeobox A 1.179
STAT1 signal transducer and activator of transcription 1, 91kDa 1.179
ALDOA aldolase A, fructose-bisphosphate 1.179
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.178
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.178
HAND2 heart and neural crest derivatives expressed 2 1.177
RICTOR RPTOR independent companion of MTOR, complex 2 1.177
IL18 interleukin 18 1.177
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.177
ERBB4 erb-b2 receptor tyrosine kinase 4 1.177
PAX2 paired box 2 1.176
NT5E 5'-nucleotidase, ecto (CD73) 1.175
MYF5 myogenic factor 5 1.173
LIMK1 LIM domain kinase 1 1.173
CIDEA cell death-inducing DFFA-like effector a 1.172
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.172
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.17
KDM4C lysine (K)-specific demethylase 4C 1.169
HSPA8 heat shock 70kDa protein 8 1.169
TOP2A topoisomerase (DNA) II alpha 170kDa 1.168
CHEK1 checkpoint kinase 1 1.168
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.167
MAPK13 mitogen-activated protein kinase 13 1.167
MBP myelin basic protein 1.166
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.166
STC1 stanniocalcin 1 1.165
GFRA2 GDNF family receptor alpha 2 1.165
IGFBP3 insulin-like growth factor binding protein 3 1.164
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.164
S100B S100 calcium binding protein B 1.164
RAD51C RAD51 paralog C 1.163
ATG7 autophagy related 7 1.163
ARG1 arginase 1 1.162
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 1.162
COMMD6 COMM domain containing 6 1.162
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 1.161
TET3 tet methylcytosine dioxygenase 3 1.16
IRS1 insulin receptor substrate 1 1.16
CCNB2 cyclin B2 1.16
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.16
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 1.159
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.159
SOX9 SRY (sex determining region Y)-box 9 1.159
FASN fatty acid synthase 1.158
KLF4 Kruppel-like factor 4 (gut) 1.158
YY1 YY1 transcription factor 1.157
TGFBR1 transforming growth factor, beta receptor 1 1.157
VBP1 von Hippel-Lindau binding protein 1 1.157
MFN1 mitofusin 1 1.156
BRD4 bromodomain containing 4 1.155
BBC3 BCL2 binding component 3 1.155
PSEN2 presenilin 2 1.153
ZBTB48 zinc finger and BTB domain containing 48 1.153
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.153
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.149
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 1.149
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 1.149
ATF4 activating transcription factor 4 1.149
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.149
LEF1 lymphoid enhancer-binding factor 1 1.149
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 1.148
ELAVL1 ELAV like RNA binding protein 1 1.148
AGTR2 angiotensin II receptor, type 2 1.147
SIGMAR1 sigma non-opioid intracellular receptor 1 1.146
NEUROD6 neuronal differentiation 6 1.146
RUNX1 runt-related transcription factor 1 1.146
FOXP3 forkhead box P3 1.145
GIPC2 GIPC PDZ domain containing family, member 2 1.142
ACSS1 acyl-CoA synthetase short-chain family member 1 1.141
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 1.141
SCTR secretin receptor 1.14
UBE2S ubiquitin-conjugating enzyme E2S 1.14
GJA1 gap junction protein, alpha 1, 43kDa 1.14
ZEB2 zinc finger E-box binding homeobox 2 1.139
MYB v-myb avian myeloblastosis viral oncogene homolog 1.139
LIF leukemia inhibitory factor 1.138
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.138
MYO5A myosin VA (heavy chain 12, myoxin) 1.138
THY1 Thy-1 cell surface antigen 1.137
NEPRO nucleolus and neural progenitor protein 1.137
BCL6 B-cell CLL/lymphoma 6 1.135
RPH3A rabphilin 3A 1.135
MAP2K2 mitogen-activated protein kinase kinase 2 1.135
G6PD glucose-6-phosphate dehydrogenase 1.135
PLAT plasminogen activator, tissue 1.134
ADNP activity-dependent neuroprotector homeobox 1.133
KDM5A lysine (K)-specific demethylase 5A 1.133
MUC16 mucin 16, cell surface associated 1.132
DLD dihydrolipoamide dehydrogenase 1.132
TBP TATA box binding protein 1.132
DPP4 dipeptidyl-peptidase 4 1.132
TRIM13 tripartite motif containing 13 1.13
AIF1 allograft inflammatory factor 1 1.128
MAPK9 mitogen-activated protein kinase 9 1.128
METTL3 methyltransferase like 3 1.126
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.125
CD80 CD80 molecule 1.125
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.123
MYO5B myosin VB 1.123
MAP1A microtubule-associated protein 1A 1.122
KDM4D lysine (K)-specific demethylase 4D 1.122
MUC1 mucin 1, cell surface associated 1.122
STAR steroidogenic acute regulatory protein 1.12
HELLS helicase, lymphoid-specific 1.119
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 1.119
LRP1B low density lipoprotein receptor-related protein 1B 1.119
VSIR V-set immunoregulatory receptor 1.119
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.118
CALB1 calbindin 1, 28kDa 1.118
MAGED1 melanoma antigen family D1 1.118
EDNRA endothelin receptor type A 1.117
F2 coagulation factor II (thrombin) 1.116
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 1.116
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.116
STMN2 stathmin 2 1.116
RB1 retinoblastoma 1 1.115
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 1.115
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.115
MC3R melanocortin 3 receptor 1.114
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.114
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.114
USP20 ubiquitin specific peptidase 20 1.113
TEK TEK tyrosine kinase, endothelial 1.113
F3 coagulation factor III (thromboplastin, tissue factor) 1.113
BMP4 bone morphogenetic protein 4 1.112
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.112
CRHR2 corticotropin releasing hormone receptor 2 1.111
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.111
CALCR calcitonin receptor 1.11
TTR transthyretin 1.11
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.109
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.108
SYN3 synapsin III 1.107
KMT2C lysine (K)-specific methyltransferase 2C 1.105
RPS6 ribosomal protein S6 1.105
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.104
DDIT4 DNA-damage-inducible transcript 4 1.103
CCNE1 cyclin E1 1.103
CARTPT CART prepropeptide 1.103
CABLES1 Cdk5 and Abl enzyme substrate 1 1.103
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.102
LAMP1 lysosomal-associated membrane protein 1 1.102
IL17A interleukin 17A 1.102
EIF4E eukaryotic translation initiation factor 4E 1.101
TXN2 thioredoxin 2 1.098
JADE1 jade family PHD finger 1 1.098
LOC112694756 uncharaterized LOC112694756 1.098
PAX6 paired box 6 1.097
RAD51 RAD51 recombinase 1.096
HDAC6 histone deacetylase 6 1.095
RBM15 RNA binding motif protein 15 1.095
CADPS Ca++-dependent secretion activator 1.095
UQCRC1 ubiquinol-cytochrome c reductase core protein I 1.094
SMAD2 SMAD family member 2 1.093
AMACR alpha-methylacyl-CoA racemase 1.093
TMEM70 transmembrane protein 70 1.091
PRMT5 protein arginine methyltransferase 5 1.091
GLI1 GLI family zinc finger 1 1.09
MNT MAX network transcriptional repressor 1.089
CXCL10 chemokine (C-X-C motif) ligand 10 1.089
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1.088
HLA-DRA major histocompatibility complex, class II, DR alpha 1.087
ELOA2 elongin A2 1.087
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.086
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.086
COX5B cytochrome c oxidase subunit Vb 1.084
CD8B CD8b molecule 1.084
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 1.083
ADRA2B adrenoceptor alpha 2B 1.082
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.082
ARID1B AT rich interactive domain 1B (SWI1-like) 1.082
H2AX H2A.X variant histone 1.082
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.081
MRAS muscle RAS oncogene homolog 1.08
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.08
VWF von Willebrand factor 1.079
ECE1 endothelin converting enzyme 1 1.079
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.079
SIRT5 sirtuin 5 1.079
TRH thyrotropin-releasing hormone 1.079
CTSB cathepsin B 1.078
HSPB3 heat shock 27kDa protein 3 1.078
RAB3C RAB3C, member RAS oncogene family 1.078
FUS FUS RNA binding protein 1.077
MMP1 matrix metallopeptidase 1 1.077
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.077
MAP2K4 mitogen-activated protein kinase kinase 4 1.076
CTSD cathepsin D 1.075
PDPN podoplanin 1.075
SPP1 secreted phosphoprotein 1 1.075
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.075
B3GAT1 beta-1,3-glucuronyltransferase 1 1.074
DLL3 delta-like 3 (Drosophila) 1.074
ELOA elongin A 1.074
MLXIP MLX interacting protein 1.073
CLU clusterin 1.073
ATF7IP activating transcription factor 7 interacting protein 1.073
PGK2 phosphoglycerate kinase 2 1.072
NOS2 nitric oxide synthase 2, inducible 1.072
NFU1 NFU1 iron-sulfur cluster scaffold 1.072
PIH1D2 PIH1 domain containing 2 1.071
ZHX2 zinc fingers and homeoboxes 2 1.071
ELN elastin 1.071
AXIN1 axin 1 1.071
TJP1 tight junction protein 1 1.071
EGR2 early growth response 2 1.07
SIRT2 sirtuin 2 1.07
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.07
USF3 upstream transcription factor family member 3 1.07
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.069
DPYSL2 dihydropyrimidinase-like 2 1.069
HCRT hypocretin (orexin) neuropeptide precursor 1.068
BTLA B and T lymphocyte associated 1.068
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.067
CUL1 cullin 1 1.067
CCNA1 cyclin A1 1.066
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 1.066
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.066
TK1 thymidine kinase 1, soluble 1.066
TPO thyroid peroxidase 1.066
LIPT1 lipoyltransferase 1 1.066
DDO D-aspartate oxidase 1.066
PI3 peptidase inhibitor 3, skin-derived 1.065
CD3D CD3d molecule, delta (CD3-TCR complex) 1.065
ASPG asparaginase 1.065
CCR8 chemokine (C-C motif) receptor 8 1.065
GPC3 glypican 3 1.064
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.064
PDGFB platelet-derived growth factor beta polypeptide 1.064
RHOG ras homolog family member G 1.063
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.063
SOS2 son of sevenless homolog 2 (Drosophila) 1.061
PDHB pyruvate dehydrogenase (lipoamide) beta 1.061
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 1.061
CD28 CD28 molecule 1.06
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.06
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.059
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 1.059
HOXB13 homeobox B13 1.057
TERF2 telomeric repeat binding factor 2 1.057
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 1.057
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.056
PAH phenylalanine hydroxylase 1.055
KMT2A lysine (K)-specific methyltransferase 2A 1.055
OLIG2 oligodendrocyte lineage transcription factor 2 1.055
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 1.054
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.054
RWDD3 RWD domain containing 3 1.054
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.054
PLG plasminogen 1.054
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.053
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 1.053
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 1.053
CRYZ crystallin, zeta (quinone reductase) 1.052
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.052
AXIN2 axin 2 1.051
MSH3 mutS homolog 3 1.051
MAP1S microtubule-associated protein 1S 1.05
AHR aryl hydrocarbon receptor 1.048
STMN1 stathmin 1 1.048
NUTM1 NUT midline carcinoma, family member 1 1.047
GH1 growth hormone 1 1.047
TMEM26 transmembrane protein 26 1.047
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.047
H2AC18 H2A clustered histone 18 1.047
TXNIP thioredoxin interacting protein 1.046
PRKG1 protein kinase, cGMP-dependent, type I 1.046
CDH5 cadherin 5, type 2 (vascular endothelium) 1.046
FGF21 fibroblast growth factor 21 1.046
NTHL1 nth endonuclease III-like 1 (E. coli) 1.046
CALR calreticulin 1.045
TPCN1 two pore segment channel 1 1.044
FLNA filamin A, alpha 1.044
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.044
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.043
TP63 tumor protein p63 1.042
CPB1 carboxypeptidase B1 (tissue) 1.042
ARF6 ADP-ribosylation factor 6 1.042
DUSP6 dual specificity phosphatase 6 1.042
H2BC21 H2B clustered histone 21 1.042
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 1.041
VTI1B vesicle transport through interaction with t-SNAREs 1B 1.04
CTRL chymotrypsin-like 1.04
ARHGAP36 Rho GTPase activating protein 36 1.039
H2AC20 H2A clustered histone 20 1.039
EXOC2 exocyst complex component 2 1.038
NOX1 NADPH oxidase 1 1.036
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 1.036
CERS2 ceramide synthase 2 1.035
ZNRF3 zinc and ring finger 3 1.034
ETV1 ets variant 1 1.034
ADAM10 ADAM metallopeptidase domain 10 1.033
HOOK3 hook microtubule-tethering protein 3 1.033
SPHK1 sphingosine kinase 1 1.033
HCRTR2 hypocretin (orexin) receptor 2 1.033
ANXA2 annexin A2 1.032
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.032
CCND2 cyclin D2 1.032
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.03
CENPA centromere protein A 1.03
FBP1 fructose-1,6-bisphosphatase 1 1.029
ASL argininosuccinate lyase 1.029
FURIN furin (paired basic amino acid cleaving enzyme) 1.029
SUZ12 SUZ12 polycomb repressive complex 2 subunit 1.028
NAPSA napsin A aspartic peptidase 1.028
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.027
GPER1 G protein-coupled estrogen receptor 1 1.027
NPR3 natriuretic peptide receptor 3 1.027
FUBP1 far upstream element (FUSE) binding protein 1 1.026
HSPB2 heat shock 27kDa protein 2 1.025
MDM4 MDM4, p53 regulator 1.025
LIPT2 lipoyl(octanoyl) transferase 2 (putative) 1.025
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.024
RALB v-ral simian leukemia viral oncogene homolog B 1.024
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 1.024
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.023
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 1.023
DIO2 deiodinase, iodothyronine, type II 1.022
PAX7 paired box 7 1.022
TRPC1 transient receptor potential cation channel, subfamily C, member 1 1.022
AURKB aurora kinase B 1.021
ATP5F1B ATP synthase F1 subunit beta 1.021
RARB retinoic acid receptor, beta 1.02
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.02
CRHR1 corticotropin releasing hormone receptor 1 1.019
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 1.018
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.018
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 1.018
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.016
CSMD3 CUB and Sushi multiple domains 3 1.016
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.016
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.015
HSPB1 heat shock 27kDa protein 1 1.015
SDC1 syndecan 1 1.015
KLLN killin, p53-regulated DNA replication inhibitor 1.014
RRAS related RAS viral (r-ras) oncogene homolog 1.014
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.014
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.013
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 1.013
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.013
UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.013
CPT1A carnitine palmitoyltransferase 1A (liver) 1.012
RECQL4 RecQ protein-like 4 1.012
PPIF peptidylprolyl isomerase F 1.01
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.01
TCF4 transcription factor 4 1.01
BMPR1A bone morphogenetic protein receptor, type IA 1.01
HDAC3 histone deacetylase 3 1.009
MMP3 matrix metallopeptidase 3 1.009
WNT3A wingless-type MMTV integration site family, member 3A 1.009
STXBP1 syntaxin binding protein 1 1.009
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.007
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.006
HMGA2 high mobility group AT-hook 2 1.006
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.006
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.006
CD200 CD200 molecule 1.006
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.005
SCARB1 scavenger receptor class B, member 1 1.005
ZNF517 zinc finger protein 517 1.005
SREBF1 sterol regulatory element binding transcription factor 1 1.004
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.003
PRODH proline dehydrogenase (oxidase) 1 1.003
MYO19 myosin XIX 1.002
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.002
RND3 Rho family GTPase 3 1.002
NRP1 neuropilin 1 1.001
LYRM4 LYR motif containing 4 1.001
CTRB1 chymotrypsinogen B1 1.0
FOXG1 forkhead box G1 1.0
GPI glucose-6-phosphate isomerase 1.0