Pilocarpine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=D010862
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Genes

180 genes/proteins interacting with the chemical Pilocarpine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACHE acetylcholinesterase (Yt blood group)
ACTB actin, beta
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADRA1B adrenoceptor alpha 1B
AGRN agrin
AIF1 allograft inflammatory factor 1
AKAP5 A kinase (PRKA) anchor protein 5
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AQP4 aquaporin 4
ATF2 activating transcription factor 2
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CCR9 chemokine (C-C motif) receptor 9
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHAT choline O-acetyltransferase
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRM4 cholinergic receptor, muscarinic 4
CLCN2 chloride channel, voltage-sensitive 2
CNN3 calponin 3, acidic
CNR1 cannabinoid receptor 1 (brain)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DMD dystrophin
DPYSL2 dihydropyrimidinase-like 2
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
EGR3 early growth response 3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EPHA5 EPH receptor A5
EZR ezrin
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FSHB follicle stimulating hormone, beta polypeptide
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAP43 growth associated protein 43
GDNF glial cell derived neurotrophic factor
GJA1 gap junction protein, alpha 1, 43kDa
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GRM5 glutamate receptor, metabotropic 5
GRM8 glutamate receptor, metabotropic 8
HMOX1 heme oxygenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IFNG interferon, gamma
IL10 interleukin 10
IL1B interleukin 1, beta
ILK integrin-linked kinase
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
ITGA1 integrin, alpha 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
JUN jun proto-oncogene
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
LAMP2 lysosomal-associated membrane protein 2
LHB luteinizing hormone beta polypeptide
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFR nerve growth factor receptor
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NPY neuropeptide Y
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGG1 8-oxoguanine DNA glycosylase
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PLCB4 phospholipase C, beta 4
PNPO pyridoxamine 5'-phosphate oxidase
POLG polymerase (DNA directed), gamma
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCZ protein kinase C, zeta
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PVALB parvalbumin
QDPR quinoid dihydropteridine reductase
RET ret proto-oncogene
RPL32 ribosomal protein L32
RPS6 ribosomal protein S6
S100B S100 calcium binding protein B
SCN2B sodium channel, voltage gated, type II beta subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SIRT1 sirtuin 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SNTA1 syntrophin, alpha 1
SOD2 superoxide dismutase 2, mitochondrial
SPARCL1 SPARC-like 1 (hevin)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SSTR3 somatostatin receptor 3
SSTR4 somatostatin receptor 4
SSTR5 somatostatin receptor 5
STAR steroidogenic acute regulatory protein
STARD6 StAR-related lipid transfer (START) domain containing 6
SYP synaptophysin
TAC1 tachykinin, precursor 1
TFAM transcription factor A, mitochondrial
TJP1 tight junction protein 1
TNF tumor necrosis factor
TNR tenascin R
TRHR thyrotropin-releasing hormone receptor
VEGFA vascular endothelial growth factor A