| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimitespib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimitespib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.214553 |
| TLE4 | transducin-like enhancer of split 4 | 0.118525 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.117594 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0929722 |
| FMN1 | formin 1 | 0.0907877 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0702206 |
| EGR1 | early growth response 1 | 0.0572823 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0543841 |
| GLCCI1 | glucocorticoid induced 1 | 0.0543543 |
| FAM107B | family with sequence similarity 107, member B | 0.0525533 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0511178 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0493154 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0476461 |
| RPL23 | ribosomal protein L23 | 0.0462931 |
| TPM1 | tropomyosin 1 (alpha) | 0.0460408 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.044907 |
| CENPF | centromere protein F, 350/400kDa | 0.0434684 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0434582 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0431831 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0422783 |
| INTS6 | integrator complex subunit 6 | 0.04218 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0419496 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0415479 |
| STK38L | serine/threonine kinase 38 like | 0.0408037 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0402465 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0400352 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0399172 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0398664 |
| THBS1 | thrombospondin 1 | 0.0388654 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0387482 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0379281 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371242 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0370459 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.036928 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0360903 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0358676 |
| MYO1E | myosin IE | 0.0358319 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0356004 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0355814 |
| RPL7 | ribosomal protein L7 | 0.0352444 |
| PCDH7 | protocadherin 7 | 0.03469 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0344764 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0337423 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0334652 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0330304 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0329628 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0328795 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0320121 |
| HOMER1 | homer scaffolding protein 1 | 0.0316878 |
| B2M | beta-2-microglobulin | 0.03148 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0312884 |
| SIK3 | SIK family kinase 3 | 0.0312791 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0310118 |
| CALD1 | caldesmon 1 | 0.0306569 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.030573 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0303533 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0296786 |
| FERMT2 | fermitin family member 2 | 0.029062 |
| BRD2 | bromodomain containing 2 | 0.0288719 |
| PDE10A | phosphodiesterase 10A | 0.0283125 |
| SIK2 | salt-inducible kinase 2 | 0.0281175 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0280469 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0278119 |
| LMNA | lamin A/C | 0.027794 |
| DIPK2A | divergent protein kinase domain 2A | 0.0277231 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0270601 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0268781 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0265533 |
| PELO | pelota homolog (Drosophila) | 0.0263924 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0260504 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0260458 |
| DST | dystonin | 0.0259527 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0258256 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0256285 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0255223 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0254585 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.025424 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0247766 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0246164 |
| OXSR1 | oxidative stress responsive 1 | 0.0245683 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0245646 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0245353 |
| RPS20 | ribosomal protein S20 | 0.0241407 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0239711 |
| BPTF | bromodomain PHD finger transcription factor | 0.0236189 |
| RBM33 | RNA binding motif protein 33 | 0.0235611 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0234038 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0233081 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0227757 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0227487 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0226533 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0225542 |
| SEPTIN7 | septin 7 | 0.022446 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0223827 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0223256 |
| FOXO3 | forkhead box O3 | 0.0223212 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0222741 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.022224 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0219979 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0219531 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.253479 |
| IGF2 | insulin-like growth factor 2 | -0.207221 |
| NRG1 | neuregulin 1 | -0.147105 |
| PTMA | prothymosin, alpha | -0.0654431 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0621282 |
| LPIN1 | lipin 1 | -0.0596764 |
| USP34 | ubiquitin specific peptidase 34 | -0.0505424 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0429197 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0423001 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0413544 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.041034 |
| AOPEP | aminopeptidase O (putative) | -0.0393153 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0392981 |
| CEP95 | centrosomal protein 95kDa | -0.0390641 |
| RPL26 | ribosomal protein L26 | -0.0387523 |
| GNAS | GNAS complex locus | -0.0382738 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0380261 |
| USP3 | ubiquitin specific peptidase 3 | -0.0359089 |
| CCND1 | cyclin D1 | -0.0357181 |
| SPAG9 | sperm associated antigen 9 | -0.035538 |
| RPS6 | ribosomal protein S6 | -0.0348 |
| TRIB2 | tribbles pseudokinase 2 | -0.0346873 |
| VIM | vimentin | -0.0346061 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0340554 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0339611 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0329962 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0328647 |
| JMJD1C | jumonji domain containing 1C | -0.0325169 |
| LDHB | lactate dehydrogenase B | -0.0325165 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0323904 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0322314 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0318097 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0317541 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.031427 |
| NREP | neuronal regeneration related protein | -0.0312937 |
| FHIT | fragile histidine triad | -0.0312202 |
| MATR3 | matrin 3 | -0.0311816 |
| RBM26 | RNA binding motif protein 26 | -0.030967 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0307758 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0300296 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0298862 |
| CADM2 | cell adhesion molecule 2 | -0.0295779 |
| WDR45B | WD repeat domain 45B | -0.0295369 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.02896 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0289489 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0281544 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0280206 |
| RPS17 | ribosomal protein S17 | -0.0278755 |
| MSI2 | musashi RNA-binding protein 2 | -0.0278019 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0274635 |
| PARD3 | par-3 family cell polarity regulator | -0.0274539 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.027453 |
| RPS16 | ribosomal protein S16 | -0.0274285 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0274262 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0272155 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0270307 |
| DYM | dymeclin | -0.027014 |
| TMSB10 | thymosin beta 10 | -0.0269806 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0267258 |
| ASPH | aspartate beta-hydroxylase | -0.0266315 |
| FNBP4 | formin binding protein 4 | -0.0266314 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0266045 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0264341 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0264138 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0264074 |
| FOXK2 | forkhead box K2 | -0.0260575 |
| SCG2 | secretogranin II | -0.0260278 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254633 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0252819 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0251173 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0249758 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0246181 |
| ANGPT1 | angiopoietin 1 | -0.0245623 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0240851 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0240508 |
| TENM3 | teneurin transmembrane protein 3 | -0.0239791 |
| AFDN | afadin, adherens junction formation factor | -0.0239753 |
| TCERG1 | transcription elongation regulator 1 | -0.0238955 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0238577 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0238077 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0236048 |
| KLHL13 | kelch-like family member 13 | -0.023423 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0234189 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.023346 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0233414 |
| RPL38 | ribosomal protein L38 | -0.0232682 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0230187 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0228643 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0226377 |
| RPS24 | ribosomal protein S24 | -0.0225996 |
| HMGA2 | high mobility group AT-hook 2 | -0.0222875 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0220623 |
| WWC2 | WW and C2 domain containing 2 | -0.0220441 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0218955 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0218915 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0216184 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0215317 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0211975 |
| ZNF804A | zinc finger protein 804A | -0.0211773 |
| COL3A1 | collagen, type III, alpha 1 | -0.0211573 |
