| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimitespib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimitespib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0699061 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0647363 |
| FOXO1 | forkhead box O1 | 0.0523294 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0491198 |
| RASAL2 | RAS protein activator like 2 | 0.0440649 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0436983 |
| MSN | moesin | 0.0403231 |
| LMO7 | LIM domain 7 | 0.0387249 |
| TGM2 | transglutaminase 2 | 0.035865 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0355824 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0347265 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0321486 |
| SVIL | supervillin | 0.0317132 |
| NRG1 | neuregulin 1 | 0.0313222 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.030827 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0300962 |
| RIN2 | Ras and Rab interactor 2 | 0.0287642 |
| IFI44L | interferon-induced protein 44-like | 0.0279034 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0278773 |
| HMGA2 | high mobility group AT-hook 2 | 0.0271755 |
| AOPEP | aminopeptidase O (putative) | 0.0268368 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0267117 |
| FOXP1 | forkhead box P1 | 0.0254863 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0251538 |
| DST | dystonin | 0.0241144 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0240408 |
| SEPTIN9 | septin 9 | 0.0240227 |
| SMAD3 | SMAD family member 3 | 0.0235624 |
| SIK3 | SIK family kinase 3 | 0.0234677 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0231637 |
| EFNA5 | ephrin-A5 | 0.0228634 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0224487 |
| LAMA5 | laminin, alpha 5 | 0.0221317 |
| BCL2L1 | BCL2-like 1 | 0.022081 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0218205 |
| NEK7 | NIMA-related kinase 7 | 0.021051 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0208736 |
| GPR176 | G protein-coupled receptor 176 | 0.0207183 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0206581 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206266 |
| CD44 | CD44 molecule (Indian blood group) | 0.0206046 |
| GOLGB1 | golgin B1 | 0.0201138 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.020097 |
| EGFR | epidermal growth factor receptor | 0.0199811 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0194686 |
| CMIP | c-Maf inducing protein | 0.0192452 |
| VEGFC | vascular endothelial growth factor C | 0.0191965 |
| SETX | senataxin | 0.018767 |
| TJP1 | tight junction protein 1 | 0.0187174 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0185887 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.017919 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0172574 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0169978 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0169422 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0168494 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0166491 |
| JAG1 | jagged 1 | 0.0166307 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0166075 |
| BPTF | bromodomain PHD finger transcription factor | 0.0165382 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0163871 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0161304 |
| AMOTL1 | angiomotin like 1 | 0.0161277 |
| PLS3 | plastin 3 | 0.0160363 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0160183 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0159604 |
| OSMR | oncostatin M receptor | 0.0159091 |
| MECOM | MDS1 and EVI1 complex locus | 0.0158687 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0158615 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0158396 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0157422 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0156331 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0152665 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.015242 |
| RPL21 | ribosomal protein L21 | 0.0152074 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0151986 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.015081 |
| PCDH1 | protocadherin 1 | 0.0150743 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.015037 |
| DIAPH1 | diaphanous-related formin 1 | 0.0149915 |
| DOK5 | docking protein 5 | 0.014921 |
| MYADM | myeloid-associated differentiation marker | 0.0146621 |
| KIAA1671 | KIAA1671 | 0.0145603 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.014554 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.014499 |
| CDK6 | cyclin-dependent kinase 6 | 0.0143659 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0142605 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0140371 |
| LUZP1 | leucine zipper protein 1 | 0.0140209 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0140141 |
| TSPAN3 | tetraspanin 3 | 0.0139247 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0138807 |
| KIAA0040 | KIAA0040 | 0.0136453 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0134873 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0134285 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0133443 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0133435 |
| TXNIP | thioredoxin interacting protein | 0.0133279 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0133138 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0133024 |
| RIGI | RNA sensor RIG-I | 0.0131056 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.28466 |
| PTMA | prothymosin, alpha | -0.155438 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.136442 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.131769 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110084 |
| NDRG1 | N-myc downstream regulated 1 | -0.10732 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0868947 |
| MEF2A | myocyte enhancer factor 2A | -0.0833098 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0824808 |
| STC1 | stanniocalcin 1 | -0.0792047 |
| TMSB10 | thymosin beta 10 | -0.0789382 |
| GNAS | GNAS complex locus | -0.0764451 |
| RPS21 | ribosomal protein S21 | -0.0759524 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0758096 |
| AHNAK | AHNAK nucleoprotein | -0.0664077 |
| H1-0 | H1.0 linker histone | -0.066367 |
| MTSS1 | metastasis suppressor 1 | -0.0605419 |
| HLA-B | major histocompatibility complex, class I, B | -0.0605072 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0595841 |
| KRT17 | keratin 17, type I | -0.0591483 |
| MT2A | metallothionein 2A | -0.059032 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0586348 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0575839 |
| RPS24 | ribosomal protein S24 | -0.0559948 |
| RBM39 | RNA binding motif protein 39 | -0.0558171 |
| RPS6 | ribosomal protein S6 | -0.0547893 |
| B2M | beta-2-microglobulin | -0.0543212 |
| S100A10 | S100 calcium binding protein A10 | -0.0542162 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0540907 |
| PODXL | podocalyxin-like | -0.0538 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0509824 |
| TMSB4X | thymosin beta 4, X-linked | -0.0503397 |
| CANX | calnexin | -0.0495116 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0493485 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0482727 |
| OGA | O-GlcNAcase | -0.0476223 |
| RPLP2 | ribosomal protein, large, P2 | -0.0469302 |
| RPS27A | ribosomal protein S27a | -0.0467951 |
| S100A6 | S100 calcium binding protein A6 | -0.0446874 |
| KIAA1217 | KIAA1217 | -0.0443976 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0442384 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.044051 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.043733 |
| ANXA1 | annexin A1 | -0.0434812 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0429931 |
| FLNB | filamin B, beta | -0.0425653 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0425289 |
| FTL | ferritin, light polypeptide | -0.0421254 |
| LDHA | lactate dehydrogenase A | -0.0420454 |
| PGK1 | phosphoglycerate kinase 1 | -0.0406331 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0402682 |
| RPS25 | ribosomal protein S25 | -0.0394208 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0393557 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0389086 |
| MXI1 | MAX interactor 1, dimerization protein | -0.038825 |
| RPL31 | ribosomal protein L31 | -0.0388127 |
| LMNA | lamin A/C | -0.0387529 |
| EMP1 | epithelial membrane protein 1 | -0.0387411 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0385186 |
| ANLN | anillin, actin binding protein | -0.038518 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0385071 |
| RPS13 | ribosomal protein S13 | -0.0382008 |
| GOLGA4 | golgin A4 | -0.0376546 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0375689 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0375237 |
| RPL32 | ribosomal protein L32 | -0.037516 |
| MT1X | metallothionein 1X | -0.0370759 |
| SPAG9 | sperm associated antigen 9 | -0.036957 |
| RPS23 | ribosomal protein S23 | -0.0369493 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.036791 |
| RPS8 | ribosomal protein S8 | -0.0366507 |
| IER3 | immediate early response 3 | -0.0364314 |
| RPL11 | ribosomal protein L11 | -0.036122 |
| CAVIN1 | caveolae associated protein 1 | -0.0360333 |
| S100A2 | S100 calcium binding protein A2 | -0.0355701 |
| RPS19 | ribosomal protein S19 | -0.0353851 |
| RPS3 | ribosomal protein S3 | -0.0350884 |
| RPL23 | ribosomal protein L23 | -0.0348996 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0346523 |
| RLF | rearranged L-myc fusion | -0.0343559 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0343083 |
| IGF2 | insulin-like growth factor 2 | -0.0341398 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0339524 |
| ARF1 | ADP-ribosylation factor 1 | -0.0339516 |
| RPL34 | ribosomal protein L34 | -0.0337673 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0334658 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327365 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0327306 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0325957 |
| RPL26 | ribosomal protein L26 | -0.0324853 |
| RPL19 | ribosomal protein L19 | -0.0320106 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0317961 |
| RPS29 | ribosomal protein S29 | -0.0314106 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0308391 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0307603 |
| RPL12 | ribosomal protein L12 | -0.0305888 |
| RAB6A | RAB6A, member RAS oncogene family | -0.03049 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0304771 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0303796 |
| RPL27A | ribosomal protein L27a | -0.0303353 |
