| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102689 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0947601 |
| LOX | lysyl oxidase | 0.0924091 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0893589 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0851879 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0842758 |
| FBN1 | fibrillin 1 | 0.0801993 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0700389 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0601905 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0548404 |
| UBC | ubiquitin C | 0.0456372 |
| C1D | C1D nuclear receptor corepressor | 0.044538 |
| CD44 | CD44 molecule (Indian blood group) | 0.0444739 |
| GPC6 | glypican 6 | 0.0439068 |
| LOXL2 | lysyl oxidase-like 2 | 0.042923 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0387038 |
| MT2A | metallothionein 2A | 0.0373951 |
| COL1A2 | collagen, type I, alpha 2 | 0.0371016 |
| AUTS2 | autism susceptibility candidate 2 | 0.0363906 |
| STC1 | stanniocalcin 1 | 0.0351968 |
| FLNA | filamin A, alpha | 0.0340871 |
| ATP13A3 | ATPase type 13A3 | 0.0336923 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.033623 |
| LDHA | lactate dehydrogenase A | 0.0330903 |
| PKM | pyruvate kinase, muscle | 0.0329566 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0322517 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0320256 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0297235 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0295224 |
| SBF2 | SET binding factor 2 | 0.0290553 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0284803 |
| MYADM | myeloid-associated differentiation marker | 0.0282073 |
| L1CAM | L1 cell adhesion molecule | 0.0281545 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0279512 |
| SQSTM1 | sequestosome 1 | 0.0276845 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0274944 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0265635 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0256905 |
| ARRDC3 | arrestin domain containing 3 | 0.0245142 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0240297 |
| NAV2 | neuron navigator 2 | 0.0239742 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0234066 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0233818 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0227705 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0225833 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0225121 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0222933 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0216366 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0211735 |
| FNIP1 | folliculin interacting protein 1 | 0.0207454 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0205267 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0202712 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0202254 |
| CTSB | cathepsin B | 0.0202194 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0201759 |
| DENND5A | DENN/MADD domain containing 5A | 0.0199509 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0198677 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0198655 |
| KIFAP3 | kinesin-associated protein 3 | 0.0197686 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0195866 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195515 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0194317 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0193696 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.019341 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0193401 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0192396 |
| ZNF207 | zinc finger protein 207 | 0.0192132 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0191064 |
| WTAP | Wilms tumor 1 associated protein | 0.0189521 |
| HIP1 | huntingtin interacting protein 1 | 0.0188595 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0187245 |
| CD109 | CD109 molecule | 0.0187119 |
| SFTPA2 | surfactant protein A2 | 0.0186375 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0186247 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0185264 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0184969 |
| LRRC49 | leucine rich repeat containing 49 | 0.0183779 |
| SETD5 | SET domain containing 5 | 0.0182579 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0180871 |
| PCGF5 | polycomb group ring finger 5 | 0.0180803 |
| TSC22D2 | TSC22 domain family, member 2 | 0.017932 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0177834 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0175683 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0174828 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0173033 |
| HELZ | helicase with zinc finger | 0.0172964 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0170974 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0170821 |
| NOTCH2 | notch 2 | 0.0169922 |
| COG5 | component of oligomeric golgi complex 5 | 0.0168627 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0168623 |
| OPTN | optineurin | 0.0167103 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0165252 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0165097 |
| PML | promyelocytic leukemia | 0.016379 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0162229 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.016183 |
| TMOD1 | tropomodulin 1 | 0.0160412 |
| DENND4C | DENN/MADD domain containing 4C | 0.0157948 |
| MNT | MAX network transcriptional repressor | 0.0157816 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.252199 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.170114 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.137967 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.130409 |
| TMSB10 | thymosin beta 10 | -0.119004 |
| CDH13 | cadherin 13 | -0.115772 |
| COL5A1 | collagen, type V, alpha 1 | -0.0823224 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0784441 |
| AHNAK | AHNAK nucleoprotein | -0.0742172 |
| FN1 | fibronectin 1 | -0.0737886 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0702747 |
| LMNA | lamin A/C | -0.0696138 |
| S100A10 | S100 calcium binding protein A10 | -0.0650118 |
| TPM4 | tropomyosin 4 | -0.0614406 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0606195 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0578593 |
| ASPH | aspartate beta-hydroxylase | -0.0474082 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0473612 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0462237 |
| PLAT | plasminogen activator, tissue | -0.0454534 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0417121 |
| PTMA | prothymosin, alpha | -0.0395243 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0393506 |
| EFNA5 | ephrin-A5 | -0.0385149 |
| CANX | calnexin | -0.0379446 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.037363 |
| CAVIN1 | caveolae associated protein 1 | -0.0369038 |
| PRSS23 | protease, serine, 23 | -0.0355734 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0353684 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0352232 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0349578 |
| TMSB4X | thymosin beta 4, X-linked | -0.0347164 |
| RRBP1 | ribosome binding protein 1 | -0.0337489 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0335565 |
| MAP1B | microtubule-associated protein 1B | -0.0333359 |
| CENPF | centromere protein F, 350/400kDa | -0.0320692 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0319908 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.031751 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0315119 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0310787 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0296007 |
| CSTB | cystatin B (stefin B) | -0.029458 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.028613 |
| EGFR | epidermal growth factor receptor | -0.0285464 |
| PLXNA2 | plexin A2 | -0.0281163 |
| RIGI | RNA sensor RIG-I | -0.0278179 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0269833 |
| DCLK2 | doublecortin-like kinase 2 | -0.0269152 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0263127 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0262014 |
| LRRC17 | leucine rich repeat containing 17 | -0.0261227 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0258776 |
| S100A6 | S100 calcium binding protein A6 | -0.0258373 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0253915 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0251913 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0245763 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.024389 |
| SUCNR1 | succinate receptor 1 | -0.0239652 |
| CCND1 | cyclin D1 | -0.0232745 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0232022 |
| MX2 | MX dynamin-like GTPase 2 | -0.0227237 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0227131 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.022707 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0224718 |
| HLA-B | major histocompatibility complex, class I, B | -0.0224203 |
| ANKRD11 | ankyrin repeat domain 11 | -0.022356 |
| IL7R | interleukin 7 receptor | -0.0220316 |
| FSTL1 | follistatin-like 1 | -0.0217432 |
| CUX1 | cut-like homeobox 1 | -0.0215319 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0209104 |
| FRMD4A | FERM domain containing 4A | -0.0207547 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0207509 |
| ENO1 | enolase 1, (alpha) | -0.020463 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0200101 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0197615 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0197043 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0195267 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0192764 |
| TPM1 | tropomyosin 1 (alpha) | -0.0189248 |
| FMN2 | formin 2 | -0.018891 |
| SEPTIN7 | septin 7 | -0.0187849 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0187045 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0186188 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0185786 |
| CALR | calreticulin | -0.0185617 |
| NAV1 | neuron navigator 1 | -0.0182508 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0182022 |
| KIAA1549L | KIAA1549-like | -0.0179206 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0179043 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0174924 |
| PCDH7 | protocadherin 7 | -0.017157 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0171379 |
| CEP170 | centrosomal protein 170kDa | -0.0171131 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0169912 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0169721 |
| SYTL3 | synaptotagmin-like 3 | -0.0168748 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0168487 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0166538 |
| SLFN5 | schlafen family member 5 | -0.0166534 |
| S100A11 | S100 calcium binding protein A11 | -0.0166326 |
